UCSF
Image of 4-quinolone

Identity 99% 90% 80% 70% Substructure

4-quinolone

PubMed — Wikipedia — Google

Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
2 1 11 9 1 1 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 63 3,989 173 2,000 2 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
Q8JXU8_9HEPC Q8JXU8 CHEMBL5375 Hepatitis C Virus NS5B RNA-dependent RNA Polymerase, 9hepc 70 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8JXU8_9HEPC Q8JXU8 CHEMBL5375 Hepatitis C Virus NS5B RNA-dependent RNA Polymerase, 9hepc 57 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 39 Annotations Catalogs SMILES SDF Mol2 Flexibase
CNR2_HUMAN P34972 CHEMBL253 Cannabinoid CB2 Receptor, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
CNR2_HUMAN P34972 CHEMBL253 Cannabinoid CB2 Receptor, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8JXU8_9HEPC Q8JXU8 CHEMBL5375 Hepatitis C Virus NS5B RNA-dependent RNA Polymerase, 9hepc 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80169 Z80169 CHEMBL614039 Huh-7 (Hepatocellular Carcinoma) 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
CNR2_HUMAN P34972 CHEMBL253 Cannabinoid CB2 Receptor, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC1_CHICK P56517 CHEMBL4582 Histone Deacetylase 1, Chick 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC2_CHICK P56519 CHEMBL4583 Histone Deacetylase 2, Chick 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC3_CHICK P56520 CHEMBL4584 Histone Deacetylase 3, Chick 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC4_CHICK P83038 CHEMBL5599 Histone Deacetylase 4, Chick 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q7YY07_CRYPV Q7YY07 CHEMBL4740 Histone Deacetylase, Crypv 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q7YY07_CRYPV Q7YY07 CHEMBL4740 Histone Deacetylase, Crypv 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDA10_HUMAN Q969S8 CHEMBL5103 Histone Deacetylase 10, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDA10_HUMAN Q969S8 CHEMBL5103 Histone Deacetylase 10, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDA11_HUMAN Q96DB2 CHEMBL3310 Histone Deacetylase 11, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDA11_HUMAN Q96DB2 CHEMBL3310 Histone Deacetylase 11, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC1_CHICK P56517 CHEMBL4582 Histone Deacetylase 1, Chick 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC1_HUMAN Q13547 CHEMBL325 Histone Deacetylase 1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC1_HUMAN Q13547 CHEMBL325 Histone Deacetylase 1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC2_CHICK P56519 CHEMBL4583 Histone Deacetylase 2, Chick 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC2_HUMAN Q92769 CHEMBL1937 Histone Deacetylase 2, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC2_HUMAN Q92769 CHEMBL1937 Histone Deacetylase 2, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC3_CHICK P56520 CHEMBL4584 Histone Deacetylase 3, Chick 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC3_HUMAN O15379 CHEMBL1829 Histone Deacetylase 3, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC3_HUMAN O15379 CHEMBL1829 Histone Deacetylase 3, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC4_CHICK P83038 CHEMBL5599 Histone Deacetylase 4, Chick 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC4_HUMAN P56524 CHEMBL3524 Histone Deacetylase 4, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC4_HUMAN P56524 CHEMBL3524 Histone Deacetylase 4, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC5_HUMAN Q9UQL6 CHEMBL2563 Histone Deacetylase 5, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC5_HUMAN Q9UQL6 CHEMBL2563 Histone Deacetylase 5, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC6_HUMAN Q9UBN7 CHEMBL1865 Histone Deacetylase 6, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC6_HUMAN Q9UBN7 CHEMBL1865 Histone Deacetylase 6, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC7_HUMAN Q8WUI4 CHEMBL2716 Histone Deacetylase 7, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC7_HUMAN Q8WUI4 CHEMBL2716 Histone Deacetylase 7, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC8_HUMAN Q9BY41 CHEMBL3192 Histone Deacetylase 8, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC8_HUMAN Q9BY41 CHEMBL3192 Histone Deacetylase 8, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC9_HUMAN Q9UKV0 CHEMBL4145 Histone Deacetylase 9, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC9_HUMAN Q9UKV0 CHEMBL4145 Histone Deacetylase 9, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q7YY76_CRYPV Q7YY76 CHEMBL3626 Histone Deacetylase, Crypv 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q7YY76_CRYPV Q7YY76 CHEMBL3626 Histone Deacetylase, Crypv 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81244 Z81244 CHEMBL614123 J774 (Macrophage Cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CHLE_HORSE P81908 CHEMBL5763 Cholinesterase, Horse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE1A_HUMAN P54750 CHEMBL3421 Phosphodiesterase 1A, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE1B_HUMAN Q01064 CHEMBL4425 Phosphodiesterase 1B, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE1C_HUMAN Q14123 CHEMBL4619 Phosphodiesterase 1C, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE3A_HUMAN Q14432 CHEMBL241 Phosphodiesterase 3A, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE3A_HUMAN Q14432 CHEMBL241 Phosphodiesterase 3A, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE3B_HUMAN Q13370 CHEMBL290 Phosphodiesterase 3B, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE3B_HUMAN Q13370 CHEMBL290 Phosphodiesterase 3B, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4C_HUMAN Q08493 CHEMBL291 Phosphodiesterase 4C, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4C_HUMAN Q08493 CHEMBL291 Phosphodiesterase 4C, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50426 Z50426 CHEMBL612856 Plasmodium Falciparum (isolate K1 / Thailand) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50677 Z50677 CHEMBL613758 Human Immunodeficiency Virus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase