Annotation Type | Substances | Purchasable | Natural | In Man |
---|---|---|---|---|
Binding ≤ 10μM | 21 | 1 | 1 | 0 |
Binding ≤ 1μM | 15 | 1 | 1 | 0 |
Reactome ID | Description | Species |
---|---|---|
REACT_198082 | Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | Gallus gallus |
REACT_198075 | Constitutive Signaling by NOTCH1 PEST Domain Mutants | Gallus gallus |
REACT_203522 | deactivation of the beta-catenin transactivating complex | Gallus gallus |
REACT_197541 | Factors involved in megakaryocyte development and platelet production | Gallus gallus |
REACT_203085 | formation of the beta-catenin:TCF transactivating complex | Gallus gallus |
REACT_197098 | G0 and Early G1 | Gallus gallus |
REACT_223355 | NoRC negatively regulates rRNA expression | Gallus gallus |
REACT_198137 | NOTCH1 Intracellular Domain Regulates Transcription | Gallus gallus |
REACT_209209 | p75NTR negatively regulates cell cycle via SC1 | Gallus gallus |
REACT_256537 | repression of WNT target genes | Gallus gallus |
REACT_248417 | RNA Polymerase I Transcription Initiation | Gallus gallus |
UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
---|---|---|---|---|---|---|---|
HDAC1_HUMAN | Q13547 | CHEMBL325 | Histone Deacetylase 1, Human | 1,826 | 45 | 16 | 13 |
HDAC1_MOUSE | O09106 | CHEMBL4001 | Histone Deacetylase 1, Mouse | 26 | 3 | 1 | 2 |
HDAC1_RAT | Q4QQW4 | CHEMBL2915 | Histone Deacetylase 1, Rat | 76 | 8 | 1 | 4 |
UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
---|---|---|---|---|---|---|---|
HDAC2_CHICK | P56519 | CHEMBL4583 | Histone Deacetylase 2, Chick | 21 | 1 | 1 | 0 |
HDAC3_CHICK | P56520 | CHEMBL4584 | Histone Deacetylase 3, Chick | 21 | 1 | 1 | 0 |
HDAC4_CHICK | P83038 | CHEMBL5599 | Histone Deacetylase 4, Chick | 21 | 1 | 1 | 0 |
Code | Description | Substances | Purchasable | Natural | In Man |
---|---|---|---|---|---|
HDAC1-1-E | Histone Deacetylase 1 (cluster #1 Of 4), Eukaryotic | 1,131 | 29 | 13 | 8 |
HDAC1-2-E | Histone Deacetylase 1 (cluster #2 Of 4), Eukaryotic | 667 | 10 | 2 | 5 |
HDAC1-3-E | Histone Deacetylase 1 (cluster #3 Of 4), Eukaryotic | 12 | 6 | 1 | 1 |
HDAC1-4-E | Histone Deacetylase 1 (cluster #4 Of 4), Eukaryotic | 98 | 3 | 0 | 0 |
Uniprot | Swissprot | Chembl | Description | Number Shared |
---|---|---|---|---|
HDAC2_CHICK | P56519 | CHEMBL4583 | Histone Deacetylase 2, Chick | 21 |
HDAC3_CHICK | P56520 | CHEMBL4584 | Histone Deacetylase 3, Chick | 21 |
HDAC4_CHICK | P83038 | CHEMBL5599 | Histone Deacetylase 4, Chick | 21 |
Q7YY76_CRYPV | Q7YY76 | CHEMBL3626 | Histone Deacetylase, Crypv | 19 |
Q7YY07_CRYPV | Q7YY07 | CHEMBL4740 | Histone Deacetylase, Crypv | 10 |
HDA10_HUMAN | Q969S8 | CHEMBL5103 | Histone Deacetylase 10, Human | 8 |
HDA11_HUMAN | Q96DB2 | CHEMBL3310 | Histone Deacetylase 11, Human | 8 |
HDAC1_HUMAN | Q13547 | CHEMBL325 | Histone Deacetylase 1, Human | 8 |
HDAC2_HUMAN | Q92769 | CHEMBL1937 | Histone Deacetylase 2, Human | 8 |
HDAC3_HUMAN | O15379 | CHEMBL1829 | Histone Deacetylase 3, Human | 8 |
HDAC4_HUMAN | P56524 | CHEMBL3524 | Histone Deacetylase 4, Human | 8 |
HDAC5_HUMAN | Q9UQL6 | CHEMBL2563 | Histone Deacetylase 5, Human | 8 |
HDAC6_HUMAN | Q9UBN7 | CHEMBL1865 | Histone Deacetylase 6, Human | 8 |
HDAC7_HUMAN | Q8WUI4 | CHEMBL2716 | Histone Deacetylase 7, Human | 8 |
HDAC8_HUMAN | Q9BY41 | CHEMBL3192 | Histone Deacetylase 8, Human | 8 |
HDAC9_HUMAN | Q9UKV0 | CHEMBL4145 | Histone Deacetylase 9, Human | 8 |
HDAH_ALCSD | Q70I53 | CHEMBL6017 | Histone Deacetylase-like Amidohydrolase, Alcsd | 1 |
NCOR2_HUMAN | Q9Y618 | CHEMBL5949 | Nuclear Receptor Corepressor 2, Human | 1 |
Q9XYC7_PLAFA | Q9XYC7 | CHEMBL5541 | Histone Deacetylase, Plafa | 1 |
TF_HUMAN | P13726 | CHEMBL4081 | Coagulation Factor III, Human | 1 |