UCSF

Pyruvate Dehydrogenase Kinase Isoform 2, Human (110 Compounds)

Swissprot:
PDK2_HUMAN
Stitch:
PDK2_HUMAN
UniProt:
Q15119
ChEMBL:
CHEMBL3861
Reactome:
REACT_12528
PDB:
2BTZ (DOCK)
2BU2 (DOCK)
2BU5 (DOCK)
2BU6 (DOCK)
2BU7 (DOCK)
2BU8 (DOCK)
PDK2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 110 2 2 1
Binding ≤ 1μM 72 0 0 1
Functional ≤ 10μM 6 0 0 1

Reactome Network (1)

Reactome ID Description Species
REACT_12528 Regulation of pyruvate dehydrogenase (PDH) complex Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 110
PDK3_HUMAN Q15120 CHEMBL3893 Pyruvate Dehydrogenase Kinase Isoform 3, Human 110
PDK4_HUMAN Q16654 CHEMBL4141 Pyruvate Dehydrogenase Kinase Isoform 4, Human 110
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PDK2_RAT Q64536 CHEMBL3601 Pyruvate Dehydrogenase Kinase Isoform 2, Rat 48 2 0 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 134 4 3 4
PDK3_HUMAN Q15120 CHEMBL3893 Pyruvate Dehydrogenase Kinase Isoform 3, Human 110 2 2 1
PDK4_HUMAN Q16654 CHEMBL4141 Pyruvate Dehydrogenase Kinase Isoform 4, Human 110 2 2 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PDK2-1-E Pyruvate Dehydrogenase Kinase Isoform 2 (cluster #1 Of 2), Eukaryotic 153 3 1 1
PDK2-2-E Pyruvate Dehydrogenase Kinase Isoform 2 (cluster #2 Of 2), Eukaryotic 5 1 1 0
Uniprot Swissprot Chembl Description Number Shared
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 110
PDK3_HUMAN Q15120 CHEMBL3893 Pyruvate Dehydrogenase Kinase Isoform 3, Human 110
PDK4_HUMAN Q16654 CHEMBL4141 Pyruvate Dehydrogenase Kinase Isoform 4, Human 110
PDK1_RAT Q63065 CHEMBL2416 Pyruvate Dehydrogenase Kinase Isoform 1, Rat 8
PDK2_RAT Q64536 CHEMBL3601 Pyruvate Dehydrogenase Kinase Isoform 2, Rat 8
Z50587 Z50587 CHEMBL372 Homo Sapiens 6
ABCC8_HUMAN Q09428 CHEMBL2071 Sulfonylurea Receptor 1, Human 4
ABCC9_HUMAN O60706 CHEMBL1971 Sulfonylurea Receptor 2, Human 4
IRK11_HUMAN Q14654 CHEMBL1886 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 11, Human 4
IRK8_HUMAN Q15842 CHEMBL4770 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 8, Human 4
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 1
Z50512 Z50512 CHEMBL369 Cavia Porcellus 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1