| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 110 | 2 | 2 | 1 |
| Binding ≤ 1μM | 72 | 0 | 0 | 1 |
| Functional ≤ 10μM | 6 | 0 | 0 | 1 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_12528 | Regulation of pyruvate dehydrogenase (PDH) complex | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| PDK1_HUMAN | Q15118 | CHEMBL4766 | Pyruvate Dehydrogenase Kinase Isoform 1, Human | 110 |
| PDK2_HUMAN | Q15119 | CHEMBL3861 | Pyruvate Dehydrogenase Kinase Isoform 2, Human | 110 |
| PDK3_HUMAN | Q15120 | CHEMBL3893 | Pyruvate Dehydrogenase Kinase Isoform 3, Human | 110 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| PDK1_HUMAN | Q15118 | CHEMBL4766 | Pyruvate Dehydrogenase Kinase Isoform 1, Human | 134 | 4 | 3 | 4 |
| PDK2_HUMAN | Q15119 | CHEMBL3861 | Pyruvate Dehydrogenase Kinase Isoform 2, Human | 110 | 2 | 2 | 1 |
| PDK3_HUMAN | Q15120 | CHEMBL3893 | Pyruvate Dehydrogenase Kinase Isoform 3, Human | 110 | 2 | 2 | 1 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| PDK4-1-E | Pyruvate Dehydrogenase Kinase Isoform 4 (cluster #1 Of 2), Eukaryotic | 113 | 1 | 1 | 1 |
| PDK4-2-E | Pyruvate Dehydrogenase Kinase Isoform 4 (cluster #2 Of 2), Eukaryotic | 5 | 1 | 1 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| PDK1_HUMAN | Q15118 | CHEMBL4766 | Pyruvate Dehydrogenase Kinase Isoform 1, Human | 110 |
| PDK2_HUMAN | Q15119 | CHEMBL3861 | Pyruvate Dehydrogenase Kinase Isoform 2, Human | 110 |
| PDK3_HUMAN | Q15120 | CHEMBL3893 | Pyruvate Dehydrogenase Kinase Isoform 3, Human | 110 |
| PDK1_RAT | Q63065 | CHEMBL2416 | Pyruvate Dehydrogenase Kinase Isoform 1, Rat | 8 |
| PDK2_RAT | Q64536 | CHEMBL3601 | Pyruvate Dehydrogenase Kinase Isoform 2, Rat | 8 |
| Z50587 | Z50587 | CHEMBL372 | Homo Sapiens | 6 |
| ABCC8_HUMAN | Q09428 | CHEMBL2071 | Sulfonylurea Receptor 1, Human | 4 |
| ABCC9_HUMAN | O60706 | CHEMBL1971 | Sulfonylurea Receptor 2, Human | 4 |
| IRK11_HUMAN | Q14654 | CHEMBL1886 | Potassium Channel, Inwardly Rectifying, Subfamily J, Member 11, Human | 4 |
| IRK8_HUMAN | Q15842 | CHEMBL4770 | Potassium Channel, Inwardly Rectifying, Subfamily J, Member 8, Human | 4 |
| LOX5_RAT | P12527 | CHEMBL312 | Arachidonate 5-lipoxygenase, Rat | 1 |
| Z50512 | Z50512 | CHEMBL369 | Cavia Porcellus | 1 |
| Z50597 | Z50597 | CHEMBL376 | Rattus Norvegicus | 1 |