UCSF

Insulin-like Growth Factor 1 Receptor, Mouse (28 Compounds)

Swissprot:
IGF1R_MOUSE
Stitch:
IGF1R_MOUSE
UniProt:
Q60751
ChEMBL:
CHEMBL5381
Reactome:
REACT_188215
REACT_188220
REACT_188219
PDB:
Igf1r

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 28 2 0 0
Binding ≤ 1μM 26 2 0 0

Reactome Network (3)

Reactome ID Description Species
REACT_188215 IRS-related events triggered by IGF1R Mus musculus
REACT_188220 SHC-related events triggered by IGF1R Mus musculus
REACT_188219 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Mus musculus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 814 45 6 7
IGF1R_RAT P24062 CHEMBL1075098 Insulin-like Growth Factor 1 Receptor, Rat 1 0 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
IGF1R-1-E Insulin-like Growth Factor 1 Receptor (cluster #1 Of 2), Eukaryotic 817 45 6 7
IGF1R-2-E Insulin-like Growth Factor 1 Receptor (cluster #2 Of 2), Eukaryotic 8 0 0 0
Uniprot Swissprot Chembl Description Number Shared
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 26
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 3
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 2
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 2
AKT1_MOUSE P31750 CHEMBL5859 RAC-alpha Serine/threonine-protein Kinase, Mouse 1
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 1
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 1
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 1
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
INSR_MOUSE P15208 CHEMBL3187 Insulin Receptor, Mouse 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 1
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 1
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 1