UCSF

CAMP-dependent Protein Kinase Type I-alpha Regulatory Subunit, Human (3 Compounds)

Swissprot:
KAP0_HUMAN
Stitch:
KAP0_HUMAN
UniProt:
P10644
ChEMBL:
CHEMBL4928
Reactome:
REACT_15334
REACT_24970
REACT_18274
REACT_15530
REACT_1946
REACT_24023
PDB:
PRKAR1A

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 3 0 0 0
Binding ≤ 1μM 0 0 0 0

Reactome Network (6)

Reactome ID Description Species
REACT_15334 DARPP-32 events Homo sapiens
REACT_24970 Factors involved in megakaryocyte development and platelet production Homo sapiens
REACT_18274 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Homo sapiens
REACT_15530 PKA activation Homo sapiens
REACT_1946 PKA activation in glucagon signalling Homo sapiens
REACT_24023 Vasopressin regulates renal water homeostasis via Aquaporins Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 3
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 3

Factors involved in megakaryocyte development and platelet production

Uniprot Swissprot Chembl Description Number Shared
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 3
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 3

Glucagon-like Peptide-1 (GLP1) regulates insulin secretion

Uniprot Swissprot Chembl Description Number Shared
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 3
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 3

PKA activation

Uniprot Swissprot Chembl Description Number Shared
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 3
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 3

PKA activation in glucagon signalling

Uniprot Swissprot Chembl Description Number Shared
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 3
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 3

Vasopressin regulates renal water homeostasis via Aquaporins

Uniprot Swissprot Chembl Description Number Shared
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 3
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3 0 0 0
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3 0 0 0
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3 0 0 0
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 247 29 9 19
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 198 23 8 18
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 195 21 8 17

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 3
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 3
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 3
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 3
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 3
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 3
KAPCA_BOVIN P00517 CHEMBL2654 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Bovin 2