UCSF

Glutamate Receptor Ionotropic, AMPA 2, Rat (671 Compounds)

Swissprot:
GRIA2_RAT
Stitch:
GRIA2_RAT
UniProt:
P19491
ChEMBL:
CHEMBL3503
PDB:
1FTJ (DOCK)
1FTK (DOCK)
1FTL (DOCK)
1FTM (DOCK)
1FTO (DOCK)
1FW0 (DOCK)
1GR2 (DOCK)
1LB8 (DOCK)
1LB9 (DOCK)
1LBB (DOCK)
1LBC (DOCK)
1M5B (DOCK)
1M5C (DOCK)
1M5D (DOCK)
1M5E (DOCK)
1M5F (DOCK)
1MM6 (DOCK)
1MM7 (DOCK)
1MQD (DOCK)
1MQG (DOCK)
1MQH (DOCK)
1MQI (DOCK)
1MQJ (DOCK)
1MS7 (DOCK)
1MXU (DOCK)
1MXV (DOCK)
1MXW (DOCK)
1MXX (DOCK)
1MXY (DOCK)
1MXZ (DOCK)
1MY0 (DOCK)
1MY1 (DOCK)
1MY2 (DOCK)
1MY3 (DOCK)
1MY4 (DOCK)
1N0T (DOCK)
1NNK (DOCK)
1NNP (DOCK)
1P1N (DOCK)
1P1O (DOCK)
1P1Q (DOCK)
1P1U (DOCK)
1P1W (DOCK)
1SYH (DOCK)
1SYI (DOCK)
1WVJ (DOCK)
1XHY (DOCK)
2AIX (DOCK)
2AL4 (DOCK)
2AL5 (DOCK)
2ANJ (DOCK)
2CMO (DOCK)
2GFE (DOCK)
2I3V (DOCK)
2I3W (DOCK)
2P2A (DOCK)
2UXA (DOCK)
2XX7 (DOCK)
2XX8 (DOCK)
2XX9 (DOCK)
2XXH (DOCK)
2XXI (DOCK)
3B6Q (DOCK)
3B6T (DOCK)
3B6W (DOCK)
3B7D (DOCK)
3BBR (DOCK)
3BFT (DOCK)
3BFU (DOCK)
3BKI (DOCK)
3DP6 (DOCK)
3H03 (DOCK)
3H06 (DOCK)
3H5V (DOCK)
3H5W (DOCK)
3H6T (DOCK)
3H6U (DOCK)
3H6V (DOCK)
3H6W (DOCK)
3HSY (DOCK)
3IJO (DOCK)
3IJX (DOCK)
3IK6 (DOCK)
3IL1 (DOCK)
3ILT (DOCK)
3ILU (DOCK)
3KG2 (DOCK)
3KGC (DOCK)
3LSF (DOCK)
3LSL (DOCK)
3M3L (DOCK)
3N6V (DOCK)
3O28 (DOCK)
3O29 (DOCK)
3O2A (DOCK)
3O2J (DOCK)
3O6G (DOCK)
3O6H (DOCK)
3O6I (DOCK)
3PD8 (DOCK)
3PD9 (DOCK)
3PMV (DOCK)
3PMW (DOCK)
3PMX (DOCK)
3RTF (DOCK)
3RTW (DOCK)
3T93 (DOCK)
3T96 (DOCK)
3T9H (DOCK)
3T9U (DOCK)
3T9V (DOCK)
3T9X (DOCK)
3TDJ (DOCK)
3TKD (DOCK)
3TZA (DOCK)
Gria2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 671 39 21 25
Binding ≤ 1μM 385 24 15 18
Functional ≤ 10μM 166 23 9 6

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 150 18 9 10
GRIA2_MOUSE P23819 CHEMBL3205 Glutamate Receptor Ionotropic, AMPA 2, Mouse 25 5 4 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GRIA1_RAT P19490 CHEMBL3753 Glutamate Receptor Ionotropic, AMPA 1, Rat 154 22 15 17
GRIA3_RAT P19492 CHEMBL3504 Glutamate Receptor Ionotropic, AMPA 3, Rat 666 37 21 25
GRIA4_RAT P19493 CHEMBL3505 Glutamate Receptor Ionotropic, AMPA 4, Rat 657 37 21 25

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
GRIA2-1-E Glutamate Receptor Ionotropic, AMPA 2 (cluster #1 Of 4), Eukaryotic 674 17 10 6
GRIA2-2-E Glutamate Receptor Ionotropic, AMPA 2 (cluster #2 Of 4), Eukaryotic 14 4 1 1
GRIA2-3-E Glutamate Receptor Ionotropic, AMPA 2 (cluster #3 Of 4), Eukaryotic 54 4 5 4
GRIA2-4-E Glutamate Receptor Ionotropic, AMPA 2 (cluster #4 Of 4), Eukaryotic 63 22 10 20
Uniprot Swissprot Chembl Description Number Shared
GRIA3_RAT P19492 CHEMBL3504 Glutamate Receptor Ionotropic, AMPA 3, Rat 776
GRIA4_RAT P19493 CHEMBL3505 Glutamate Receptor Ionotropic, AMPA 4, Rat 766
GRIA1_MOUSE P23818 CHEMBL3502 Glutamate Receptor Ionotropic, AMPA 1, Mouse 598
GRIA1_RAT P19490 CHEMBL3753 Glutamate Receptor Ionotropic, AMPA 1, Rat 226
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 168
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 152
GRIK1_RAT P22756 CHEMBL2919 Glutamate Receptor Ionotropic Kainate 1, Rat 97
GRIK3_RAT P42264 CHEMBL3744 Glutamate Receptor Ionotropic Kainate 3, Rat 74
GRIK4_RAT Q01812 CHEMBL3044 Glutamate Receptor Ionotropic Kainate 4, Rat 71
GRIK5_RAT Q63273 CHEMBL4041 Glutamate Receptor Ionotropic Kainate 5, Rat 71
GRIK2_RAT P42260 CHEMBL3607 Glutamate Receptor Ionotropic Kainate 2, Rat 70
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 43
GRIA1_HUMAN P42261 CHEMBL2009 Glutamate Receptor Ionotropic, AMPA 1, Human 42
GRIA4_HUMAN P48058 CHEMBL3190 Glutamate Receptor Ionotropic, AMPA 4, Human 39
NMD3A_RAT Q9R1M7 CHEMBL342 Glutamate [NMDA] Receptor Subunit 3A, Rat 38
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 38
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat 38
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 38
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 38
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 36
GRIA3_HUMAN P42263 CHEMBL3595 Glutamate Receptor Ionotropic, AMPA 3, Human 30
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 22
GRIK1_HUMAN P39086 CHEMBL1918 Glutamate Receptor Ionotropic Kainate 1, Human 20
GRIK5_HUMAN Q16478 CHEMBL2675 Glutamate Receptor Ionotropic Kainate 5, Human 19
GRIK2_HUMAN Q13002 CHEMBL3683 Glutamate Receptor Ionotropic Kainate 2, Human 10
GRIK3_HUMAN Q13003 CHEMBL3684 Glutamate Receptor Ionotropic Kainate 3, Human 9
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 8
GRIA2_MOUSE P23819 CHEMBL3205 Glutamate Receptor Ionotropic, AMPA 2, Mouse 7
GRIA3_MOUSE Q9Z2W9 CHEMBL3624 Glutamate Receptor Ionotropic, AMPA 3, Mouse 7
GRIA4_MOUSE Q9Z2W8 CHEMBL3615 Glutamate Receptor Ionotropic, AMPA 4, Mouse 7
GRIK4_HUMAN Q16099 CHEMBL2829 Glutamate Receptor Ionotropic Kainate 4, Human 7
GRM8_MOUSE P47743 CHEMBL4626 Metabotropic Glutamate Receptor 8, Mouse 5
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 5
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 5
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 5
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 5
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 5
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 5
GLRA1_RAT P07727 CHEMBL3246 Glycine Receptor Alpha-1 Chain, Rat 4
GLRA2_RAT P22771 CHEMBL2328 Glycine Receptor Alpha-2 Chain, Rat 4
GLRA3_RAT P24524 CHEMBL2677 Glycine Receptor Alpha-3 Chain, Rat 4
GLRB_RAT P20781 CHEMBL4126 Glycine Receptor Beta Chain, Rat 4
GRM1_MOUSE P97772 CHEMBL2892 Metabotropic Glutamate Receptor 1, Mouse 4
GRM3_MOUSE Q9QYS2 CHEMBL3824 Metabotropic Glutamate Receptor 3, Mouse 4
GRM7_MOUSE Q68ED2 CHEMBL3966 Metabotropic Glutamate Receptor 7, Mouse 4
Q80T35_MOUSE Q80T35 CHEMBL3033 Metabotropic Glutamate Receptor 6, Mouse 4
Q80T43_MOUSE Q80T43 CHEMBL3779 Metabotropic Glutamate Receptor 2, Mouse 4
Q80T47_MOUSE Q80T47 CHEMBL2832 Metabotropic Glutamate Receptor 5, Mouse 4
Z50574 Z50574 CHEMBL612667 Xenopus Sp. 4
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 3
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic Glutamate Receptor 1, Human 3
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 3
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 3
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 3
GLRA4_MOUSE Q61603 CHEMBL3500 Glycine Receptor Alpha-4 Chain, Mouse 2
GRID1_HUMAN Q9ULK0 CHEMBL2936 Glutamate Receptor Delta-1 Subunit, Human 2
GRIK2_XENLA Q91755 CHEMBL3395 Glutamate Receptor Ionotropic Kainate 2, Xenla 2
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 2
GRM2_RAT P31421 CHEMBL2851 Metabotropic Glutamate Receptor 2, Rat 2
GRM3_RAT P31422 CHEMBL3067 Metabotropic Glutamate Receptor 3, Rat 2
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic Glutamate Receptor 4, Human 2
GRM8_RAT P70579 CHEMBL2718 Metabotropic Glutamate Receptor 8, Rat 2
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 2
EAA3_HUMAN P43005 CHEMBL2721 Excitatory Amino Acid Transporter 3, Human 1
FOLH1_HUMAN Q04609 CHEMBL1892 Glutamate Carboxypeptidase II, Human 1
GRM3_HUMAN Q14832 CHEMBL2888 Metabotropic Glutamate Receptor 3, Human 1
GRM4_RAT P31423 CHEMBL2787 Metabotropic Glutamate Receptor 4, Rat 1
GRM6_HUMAN O15303 CHEMBL4573 Metabotropic Glutamate Receptor 6, Human 1
GRM6_RAT P35349 CHEMBL3842 Metabotropic Glutamate Receptor 6, Rat 1
GRM8_HUMAN O00222 CHEMBL3228 Metabotropic Glutamate Receptor 8, Human 1
MURI_HELPY P56068 CHEMBL6078 Glutamate Racemase, Helpy 1
XCT_HUMAN Q9UPY5 CHEMBL1075149 Cystine/glutamate Transporter, Human 1
Z50501 Z50501 CHEMBL613109 Gallus Gallus 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 1