| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 3 | 1 | 1 | 1 |
| Binding ≤ 1μM | 3 | 1 | 1 | 1 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_198969 | Activation of gene expression by SREBF (SREBP) | Mus musculus |
| REACT_208531 | Cholesterol biosynthesis | Mus musculus |
| REACT_198602 | PPARA activates gene expression | Mus musculus |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| HMDH_HUMAN | P04035 | CHEMBL402 | HMG-CoA Reductase, Human | 232 | 23 | 14 | 12 |
| HMDH_MESAU | P09610 | CHEMBL1075267 | 3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Mesau | 3 | 0 | 0 | 0 |
| HMDH_RAT | P51639 | CHEMBL3247 | HMG-CoA Reductase, Rat | 925 | 28 | 10 | 10 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| HMDH-1-E | HMG-CoA Reductase (cluster #1 Of 2), Eukaryotic | 535 | 36 | 15 | 13 |
| HMDH-2-E | HMG-CoA Reductase (cluster #2 Of 2), Eukaryotic | 580 | 10 | 8 | 8 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| HMDH_HUMAN | P04035 | CHEMBL402 | HMG-CoA Reductase, Human | 3 |
| HMDH_RAT | P51639 | CHEMBL3247 | HMG-CoA Reductase, Rat | 3 |