UCSF

Heat Shock Protein HSP 90-alpha, Mouse (38 Compounds)

Swissprot:
HS90A_MOUSE
Stitch:
HS90A_MOUSE
UniProt:
P07901
ChEMBL:
CHEMBL4197
Reactome:
REACT_223784
REACT_221264
REACT_243939
REACT_225256
REACT_213550
REACT_243078
REACT_244487
REACT_245720
REACT_198374
REACT_196635
REACT_196603
REACT_254306
REACT_199123
REACT_188191
REACT_199047
REACT_257088
REACT_261840
PDB:
Hsp90aa1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 38 0 0 0
Binding ≤ 1μM 10 0 0 0

Reactome Network (17)

Reactome ID Description Species
REACT_223784 Attenuation phase Mus musculus
REACT_221264 eNOS activation Mus musculus
REACT_243939 EPHA-mediated growth cone collapse Mus musculus
REACT_225256 HSF1 activation Mus musculus
REACT_213550 HSF1-dependent transactivation Mus musculus
REACT_243078 Loss of Nlp from mitotic centrosomes Mus musculus
REACT_244487 Loss of proteins required for interphase microtubule organization from the ce Mus musculus
REACT_245720 Recruitment of mitotic centrosome proteins and complexes Mus musculus
REACT_198374 Regulation of actin dynamics for phagocytic cup formation Mus musculus
REACT_196635 Regulation of PLK1 Activity at G2/M Transition Mus musculus
REACT_196603 Scavenging by Class F Receptors Mus musculus
REACT_254306 Sema3A PAK dependent Axon repulsion Mus musculus
REACT_199123 Signaling by constitutively active EGFR Mus musculus
REACT_188191 Signaling by ERBB2 Mus musculus
REACT_199047 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation Mus musculus
REACT_257088 VEGFA-VEGFR2 Pathway Mus musculus
REACT_261840 VEGFR2 mediated vascular permeability Mus musculus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
HS90A_HUMAN P07900 CHEMBL3880 Heat Shock Protein HSP 90-alpha, Human 236 34 8 18

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
HS90A-1-E Heat Shock Protein HSP 90-alpha (cluster #1 Of 4), Eukaryotic 107 6 5 3
HS90A-2-E Heat Shock Protein HSP 90-alpha (cluster #2 Of 4), Eukaryotic 157 24 3 15
HS90A-3-E Heat Shock Protein HSP 90-alpha (cluster #3 Of 4), Eukaryotic 7 3 0 0
HS90A-4-E Heat Shock Protein HSP 90-alpha (cluster #4 Of 4), Eukaryotic 1 1 0 0
Uniprot Swissprot Chembl Description Number Shared
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 2
HS90A_HUMAN P07900 CHEMBL3880 Heat Shock Protein HSP 90-alpha, Human 2
HS90B_HUMAN P08238 CHEMBL4303 Heat Shock Protein HSP 90-beta, Human 2