UCSF

Inositol 1,4,5-trisphosphate 5-phosphatase, Human (5 Compounds)

Swissprot:
I5P2_HUMAN
Stitch:
I5P2_HUMAN
UniProt:
P32019
ChEMBL:
CHEMBL2636
Reactome:
REACT_11051
REACT_150352
REACT_150312
PDB:
3MTC (DOCK)
3N9V (DOCK)
INPP5B

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 5 0 0 0
Binding ≤ 1μM 5 0 0 0

Reactome Network (3)

Reactome ID Description Species
REACT_11051 Rho GTPase cycle Homo sapiens
REACT_150352 Synthesis of IP2, IP, and Ins in the cytosol Homo sapiens
REACT_150312 Synthesis of IP3 and IP4 in the cytosol Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
I5P1_HUMAN Q14642 CHEMBL4243 Type I Inositol-1,4,5-trisphosphate 5-phosphatase, Human 5

Synthesis of IP3 and IP4 in the cytosol

Uniprot Swissprot Chembl Description Number Shared
IP3KA_HUMAN P23677 CHEMBL5164 Inositol-trisphosphate 3-kinase A, Human 4
IP3KB_HUMAN P27987 CHEMBL5165 Inositol-trisphosphate 3-kinase B, Human 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
I5P1_HUMAN Q14642 CHEMBL4243 Type I Inositol-1,4,5-trisphosphate 5-phosphatase, Human 13 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
I5P1_HUMAN Q14642 CHEMBL4243 Type I Inositol-1,4,5-trisphosphate 5-phosphatase, Human 5
IP3KA_HUMAN P23677 CHEMBL5164 Inositol-trisphosphate 3-kinase A, Human 4
IP3KB_HUMAN P27987 CHEMBL5165 Inositol-trisphosphate 3-kinase B, Human 4
IP3KC_RAT Q80ZG2 CHEMBL2667 Inositol 1,4,5-trisphosphate 3 Kinase C, Rat 4
P79248_PIG P79248 CHEMBL2950 Type 1 InsP3 Receptor Isoform S2, Pig 4