UCSF

Type 1 InsP3 Receptor Isoform S2, Pig (16 Compounds)

Swissprot:
P79248_PIG
Stitch:
P79248_PIG
UniProt:
P79248
ChEMBL:
CHEMBL2950
Reactome:
REACT_193228
REACT_191877
REACT_213148
REACT_193175
REACT_258432
REACT_233291
REACT_193232
REACT_203789
REACT_236586
REACT_236907
REACT_193554
REACT_241438

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 16 4 4 4
Binding ≤ 1μM 8 4 4 4

Reactome Network (12)

Reactome ID Description Species
REACT_193228 Antigen activates B Cell Receptor (BCR) leading to generation of second messenge Sus scrofa
REACT_191877 Ca2+ pathway Sus scrofa
REACT_213148 cGMP effects Sus scrofa
REACT_193175 DAG and IP3 signaling Sus scrofa
REACT_258432 Effects of PIP2 hydrolysis Sus scrofa
REACT_233291 Elevation of cytosolic Ca2+ levels Sus scrofa
REACT_193232 FCERI mediated Ca+2 mobilization Sus scrofa
REACT_203789 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Sus scrofa
REACT_236586 PLC beta mediated events Sus scrofa
REACT_236907 Regulation of insulin secretion Sus scrofa
REACT_193554 Role of phospholipids in phagocytosis Sus scrofa
REACT_241438 VEGFR2 mediated cell proliferation Sus scrofa
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PA21B_PIG P00592 CHEMBL4715 Phospholipase A2 Group 1B, Pig 35 4 1 1
PEPA_PIG P00791 CHEMBL2714 Pepsin A, Pig 253 1 0 0
PPCE_PIG P23687 CHEMBL2461 Prolyl Endopeptidase, Pig 106 5 0 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
IP3KC_RAT Q80ZG2 CHEMBL2667 Inositol 1,4,5-trisphosphate 3 Kinase C, Rat 8
I5P1_HUMAN Q14642 CHEMBL4243 Type I Inositol-1,4,5-trisphosphate 5-phosphatase, Human 4
I5P2_HUMAN P32019 CHEMBL2636 Inositol 1,4,5-trisphosphate 5-phosphatase, Human 4
IP3KA_HUMAN P23677 CHEMBL5164 Inositol-trisphosphate 3-kinase A, Human 4
IP3KA_RAT P17105 CHEMBL3261 Inositol-trisphosphate 3-kinase A, Rat 4
IP3KB_HUMAN P27987 CHEMBL5165 Inositol-trisphosphate 3-kinase B, Human 4
IP3KB_RAT P42335 CHEMBL3307 Inositol-trisphosphate 3-kinase B, Rat 4
ITPR1_BOVIN Q9TU34 CHEMBL2509 Inositol 1,4,5-trisphosphate Receptor Type 1, Bovin 4
ITPR1_HUMAN Q14643 CHEMBL4046 Inositol 1,4,5-trisphosphate Receptor Type 1, Human 4
ITPR1_RAT P29994 CHEMBL2804 Inositol 1,4,5-trisphosphate Receptor Type 1, Rat 4
ITPR2_BOVIN Q8WN96 CHEMBL3112 Inositol 1,4,5-trisphosphate Receptor Type 2, Bovin 4
ITPR2_HUMAN Q14571 CHEMBL2512 Inositol 1,4,5-trisphosphate Receptor Type 2, Human 4
ITPR2_RAT P29995 CHEMBL2537 Inositol 1,4,5-trisphosphate Receptor Type 2, Rat 4
ITPR3_BOVIN Q8WN95 CHEMBL2853 Inositol 1,4,5-trisphosphate Receptor Type 3, Bovin 4
ITPR3_HUMAN Q14573 CHEMBL3904 Inositol 1,4,5-trisphosphate Receptor Type 3, Human 4
ITPR3_RAT Q63269 CHEMBL2846 Inositol 1,4,5-trisphosphate Receptor Type 3, Rat 4
PLCL1_RAT Q62688 CHEMBL3364 Inositol 1,4,5-trisphosphate Binding Protein, Rat 4