UCSF

Integrin Beta-6, Human (213 Compounds)

Swissprot:
ITB6_HUMAN
Stitch:
ITB6_HUMAN
UniProt:
P18564
ChEMBL:
CHEMBL4876
Reactome:
REACT_163906
REACT_150366
REACT_13552
REACT_150331
PDB:
1LH9 (DOCK)
ITGB6

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 213 0 0 0
Binding ≤ 1μM 104 0 0 0
Functional ≤ 10μM 30 0 0 0

Reactome Network (4)

Reactome ID Description Species
REACT_163906 ECM proteoglycans Homo sapiens
REACT_150366 Elastic fibre formation Homo sapiens
REACT_13552 Integrin cell surface interactions Homo sapiens
REACT_150331 Molecules associated with elastic fibres Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 83
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 213
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 15
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 83
ITB5_HUMAN P18084 CHEMBL2600 Integrin Beta-5, Human 98

Elastic fibre formation

Uniprot Swissprot Chembl Description Number Shared
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 213
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 15
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 83

Integrin cell surface interactions

Uniprot Swissprot Chembl Description Number Shared
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 83
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 213
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 15
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 83
ITB5_HUMAN P18084 CHEMBL2600 Integrin Beta-5, Human 98

Molecules associated with elastic fibres

Uniprot Swissprot Chembl Description Number Shared
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 213
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 15
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 83
ITB5_HUMAN P18084 CHEMBL2600 Integrin Beta-5, Human 98
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 249 1 0 0
ITB2_HUMAN P05107 CHEMBL3631 Integrin Beta-2, Human 207 5 0 0
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 1,479 4 8 8
ITB5_HUMAN P18084 CHEMBL2600 Integrin Beta-5, Human 280 0 0 1
ITB7_HUMAN P26010 CHEMBL2979 Integrin Beta-7, Human 355 9 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 213
Z104292 Z104292 CHEMBL1907598 Integrin Alpha-V/beta-3 213
ITB5_HUMAN P18084 CHEMBL2600 Integrin Beta-5, Human 98
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 83
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 83
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 15