UCSF

Tyrosine-protein Kinase Lyn, Rat (1 Compounds)

Swissprot:
LYN_RAT
Stitch:
LYN_RAT
UniProt:
Q07014
ChEMBL:
CHEMBL4363
Reactome:
REACT_211910
REACT_258816
REACT_234191
REACT_244383
REACT_257657
REACT_243826
REACT_256777
REACT_241561
REACT_213009
REACT_203734
REACT_195202
REACT_197513
REACT_198646
REACT_230090
REACT_196425
REACT_247641
REACT_197451
REACT_197531
REACT_195025
PDB:
Lyn

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1 1 1 1
Binding ≤ 1μM 0 0 0 0

Reactome Network (19)

Reactome ID Description Species
REACT_211910 Antigen activates B Cell Receptor (BCR) leading to generation of second messenge Rattus norvegicus
REACT_258816 CD28 co-stimulation Rattus norvegicus
REACT_234191 Cell surface interactions at the vascular wall Rattus norvegicus
REACT_244383 CTLA4 inhibitory signaling Rattus norvegicus
REACT_257657 EPH-ephrin mediated repulsion of cells Rattus norvegicus
REACT_243826 EPH-Ephrin signaling Rattus norvegicus
REACT_256777 EPHA-mediated growth cone collapse Rattus norvegicus
REACT_241561 EPHB-mediated forward signaling Rattus norvegicus
REACT_213009 Fc epsilon receptor (FCERI) signaling Rattus norvegicus
REACT_203734 FCERI mediated Ca+2 mobilization Rattus norvegicus
REACT_195202 FCERI mediated MAPK activation Rattus norvegicus
REACT_197513 FCERI mediated NF-kB activation Rattus norvegicus
REACT_198646 FCGR activation Rattus norvegicus
REACT_230090 GPVI-mediated activation cascade Rattus norvegicus
REACT_196425 Growth hormone receptor signaling Rattus norvegicus
REACT_247641 Platelet Adhesion to exposed collagen Rattus norvegicus
REACT_197451 Regulation of KIT signaling Rattus norvegicus
REACT_197531 Role of LAT2/NTAL/LAB on calcium mobilization Rattus norvegicus
REACT_195025 Signaling by SCF-KIT Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
FGR_RAT Q6P6U0 CHEMBL4362 Tyrosine-protein Kinase FGR, Rat 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 226 32 13 20

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 1
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 1
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 1
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 1
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 1
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 1
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 1
CSK21_RAT P19139 CHEMBL2661 Casein Kinase II Alpha, Rat 1
CSK2B_RAT P67874 CHEMBL2463 Casein Kinase II Beta, Rat 1
ERG1_RAT P52020 CHEMBL4241 Squalene Monooxygenase, Rat 1
FGR_RAT Q6P6U0 CHEMBL4362 Tyrosine-protein Kinase FGR, Rat 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 1
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 1
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 1
KSYK_RAT Q64725 CHEMBL4364 Tyrosine-protein Kinase SYK, Rat 1
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 1
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 1