UCSF

Purinergic Receptor P2Y12, Human (611 Compounds)

Swissprot:
P2Y12_HUMAN
Stitch:
P2Y12_HUMAN
UniProt:
Q9H244
ChEMBL:
CHEMBL2001
Reactome:
REACT_20653
REACT_19231
REACT_18289
PDB:
1T78 (DOCK)
1VZ1 (DOCK)
1Y9C (DOCK)
P2RY12

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 611 10 0 0
Binding ≤ 1μM 545 5 0 0
Functional ≤ 10μM 265 2 4 3

Reactome Network (3)

Uniprot Swissprot Chembl Description Number Shared
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 1
P2RY4_HUMAN P51582 CHEMBL2123 Pyrimidinergic Receptor P2Y4, Human 4

P2Y receptors

Uniprot Swissprot Chembl Description Number Shared
P2RY2_HUMAN P41231 CHEMBL4398 Purinergic Receptor P2Y2, Human 7
P2RY4_HUMAN P51582 CHEMBL2123 Pyrimidinergic Receptor P2Y4, Human 4
P2RY6_HUMAN Q15077 CHEMBL4714 Pyrimidinergic Receptor P2Y6, Human 4
P2Y11_HUMAN Q96G91 CHEMBL4867 Purinergic Receptor P2Y11, Human 2

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
P2Y12-1-E Purinergic Receptor P2Y12 (cluster #1 Of 2), Eukaryotic 602 10 0 0
P2Y12-2-E Purinergic Receptor P2Y12 (cluster #2 Of 2), Eukaryotic 8 0 0 0
Uniprot Swissprot Chembl Description Number Shared
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 71
5NTD_RAT P21588 CHEMBL1075214 5'-nucleotidase, Rat 5
Z50587 Z50587 CHEMBL372 Homo Sapiens 4
O77823_PIG O77823 CHEMBL3333 Phosphodiesterase 4A, Pig 2
P2Y11_HUMAN Q96G91 CHEMBL4867 Purinergic Receptor P2Y11, Human 2
PDE3A_HUMAN Q14432 CHEMBL241 Phosphodiesterase 3A, Human 2
PDE3B_HUMAN Q13370 CHEMBL290 Phosphodiesterase 3B, Human 2
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 1
Z102352 Z102352 CHEMBL613652 Plasma 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1