UCSF

Prostanoid EP1 Receptor, Human (213 Compounds)

Swissprot:
PE2R1_HUMAN
Stitch:
PE2R1_HUMAN
UniProt:
P34995
ChEMBL:
CHEMBL1811
Reactome:
REACT_18283
REACT_18425
PDB:
PTGER1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 213 6 3 4
Binding ≤ 1μM 140 5 2 3
Functional ≤ 10μM 22 4 1 2

Reactome Network (2)

Uniprot Swissprot Chembl Description Number Shared
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 40
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 32

Prostanoid ligand receptors

Uniprot Swissprot Chembl Description Number Shared
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 1
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 13
PE2R2_HUMAN P43116 CHEMBL1881 Prostanoid EP2 Receptor, Human 60
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 88
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 64
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 40
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP Receptor, Human 9
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 32
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PE2R1_MOUSE P35375 CHEMBL2181 Prostanoid EP1 Receptor, Mouse 62 3 3 3
PE2R1_RAT P70597 CHEMBL5068 Prostanoid EP1 Receptor, Rat 2 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PE2R2_HUMAN P43116 CHEMBL1881 Prostanoid EP2 Receptor, Human 193 10 3 3
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 475 9 3 4
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 376 7 2 2

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PE2R1-1-E Prostanoid EP1 Receptor (cluster #1 Of 2), Eukaryotic 233 3 1 1
PE2R1-2-E Prostanoid EP1 Receptor (cluster #2 Of 2), Eukaryotic 42 6 5 6
Uniprot Swissprot Chembl Description Number Shared
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 87
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 64
PE2R2_HUMAN P43116 CHEMBL1881 Prostanoid EP2 Receptor, Human 60
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 39
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 30
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 12
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP Receptor, Human 9
PE2R3_MOUSE P30557 CHEMBL4336 Prostanoid EP3 Receptor, Mouse 4
PE2R1_RAT P70597 CHEMBL5068 Prostanoid EP1 Receptor, Rat 2
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
PE2R2_RAT Q62928 CHEMBL4909 Prostanoid EP2 Receptor, Rat 1
PE2R3_RAT P34980 CHEMBL5674 Prostaglandin E2 Receptor EP3 Subtype, Rat 1
PE2R4_RAT P43114 CHEMBL4086 Prostanoid EP4 Receptor, Rat 1
PF2R_BOVIN P37289 CHEMBL4820 Prostanoid FP Receptor, Bovin 1
PF2R_MOUSE P43117 CHEMBL5000 Prostaglandin F2-alpha Receptor, Mouse 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
S22A6_MOUSE Q8VC69 CHEMBL5653 Solute Carrier Family 22 Member 6, Mouse 1
TYPH_HUMAN P19971 CHEMBL3106 Thymidine Phosphorylase, Human 1
Z50589 Z50589 CHEMBL612670 Felis Catus 1
Z80530 Z80530 CHEMBL614946 Swiss-3T3 (Fibroblast Cells) 1