UCSF

Prostaglandin E Synthase, Human (234 Compounds)

Swissprot:
PTGES_HUMAN
Stitch:
PTGES_HUMAN
UniProt:
O14684
ChEMBL:
CHEMBL5658
Reactome:
REACT_150149
PDB:
3DWW (DOCK)
PTGES

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 234 16 0 1
Binding ≤ 1μM 130 1 0 0

Reactome Network (1)

Reactome ID Description Species
REACT_150149 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AK1C3_HUMAN P42330 CHEMBL4681 Aldo-keto-reductase Family 1 Member C3, Human 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1
THAS_HUMAN P24557 CHEMBL1835 Thromboxane-A Synthase, Human 5

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PTGES-1-E Prostaglandin E Synthase (cluster #1 Of 2), Eukaryotic 203 18 0 1
PTGES-2-E Prostaglandin E Synthase (cluster #2 Of 2), Eukaryotic 37 0 0 0
Uniprot Swissprot Chembl Description Number Shared
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 84
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 12
PGES2_HUMAN Q9H7Z7 CHEMBL4411 Prostaglandin E Synthase 2, Human 10
THAS_HUMAN P24557 CHEMBL1835 Thromboxane-A Synthase, Human 4
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 2
AK1C3_HUMAN P42330 CHEMBL4681 Aldo-keto-reductase Family 1 Member C3, Human 1
AL5AP_HUMAN P20292 CHEMBL4550 5-lipoxygenase Activating Protein, Human 1
PGH1_BOVIN O62664 CHEMBL2860 Cyclooxygenase-1, Bovin 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
PGH2_BOVIN O62698 CHEMBL3331 Cyclooxygenase-2, Bovin 1
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1
Q2TJZ7_PIG Q2TJZ7 CHEMBL5152 Microsomal Prostaglandin E Synthase-1, Pig 1
Q9BEG3_BOVIN Q9BEG3 CHEMBL2980 Arachidonate 5-lipoxygenase, Bovin 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1

Most Common Rings