UCSF

Ras-related C3 Botulinum Toxin Substrate 1, Human (3 Compounds)

Swissprot:
RAC1_HUMAN
Stitch:
RAC1_HUMAN
UniProt:
P63000
ChEMBL:
CHEMBL6094
Reactome:
REACT_19226
REACT_19238
REACT_147814
REACT_22351
REACT_25299
REACT_228189
REACT_228085
REACT_228226
REACT_24970
REACT_163701
REACT_18407
REACT_1695
REACT_19342
REACT_11068
REACT_13638
REACT_172581
REACT_160086
REACT_19236
REACT_19279
REACT_19277
REACT_19266
REACT_22272
REACT_111040
REACT_147867
REACT_228166
REACT_228016
PDB:
1E96 (DOCK)
1FOE (DOCK)
1G4U (DOCK)
1HE1 (DOCK)
1HH4 (DOCK)
1I4D (DOCK)
1I4L (DOCK)
1I4T (DOCK)
1MH1 (DOCK)
1RYF (DOCK)
1RYH (DOCK)
2FJU (DOCK)
2H7V (DOCK)
2NZ8 (DOCK)
2P2L (DOCK)
2RMK (DOCK)
2VRW (DOCK)
2WKP (DOCK)
2WKQ (DOCK)
2WKR (DOCK)
2YIN (DOCK)
3BJI (DOCK)
3RYT (DOCK)
3SU8 (DOCK)
3SUA (DOCK)
RAC1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 3 0 1 0
Binding ≤ 1μM 0 0 0 0

Reactome Network (26)

Reactome ID Description Species
REACT_19226 Activation of Rac Homo sapiens
REACT_19238 CD28 dependent Vav1 pathway Homo sapiens
REACT_147814 DAP12 signaling Homo sapiens
REACT_22351 DCC mediated attractive signaling Homo sapiens
REACT_25299 DSCAM interactions Homo sapiens
REACT_228189 EPH-ephrin mediated repulsion of cells Homo sapiens
REACT_228085 EPHB-mediated forward signaling Homo sapiens
REACT_228226 Ephrin signaling Homo sapiens
REACT_24970 Factors involved in megakaryocyte development and platelet production Homo sapiens
REACT_163701 FCERI mediated MAPK activation Homo sapiens
REACT_18407 G alpha (12/13) signalling events Homo sapiens
REACT_1695 GPVI-mediated activation cascade Homo sapiens
REACT_19342 Inactivation of Cdc42 and Rac Homo sapiens
REACT_11068 Nef and signal transduction Homo sapiens
REACT_13638 NRAGE signals death through JNK Homo sapiens
REACT_172581 PCP/CE pathway Homo sapiens
REACT_160086 Regulation of actin dynamics for phagocytic cup formation Homo sapiens
REACT_19236 Sema3A PAK dependent Axon repulsion Homo sapiens
REACT_19279 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Homo sapiens
REACT_19277 Sema4D induced cell migration and growth-cone collapse Homo sapiens
REACT_19266 Sema4D mediated inhibition of cell attachment and migration Homo sapiens
REACT_22272 Signal transduction by L1 Homo sapiens
REACT_111040 Signaling by SCF-KIT Homo sapiens
REACT_147867 Translocation of GLUT4 to the plasma membrane Homo sapiens
REACT_228166 VEGFA-VEGFR2 Pathway Homo sapiens
REACT_228016 VEGFR2 mediated vascular permeability Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 2

DCC mediated attractive signaling

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 2

EPHB-mediated forward signaling

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 2

Factors involved in megakaryocyte development and platelet production

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 2

G alpha (12/13) signalling events

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 2

GPVI-mediated activation cascade

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 2

Inactivation of Cdc42 and Rac

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 2

Regulation of actin dynamics for phagocytic cup formation

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 2

Sema4D induced cell migration and growth-cone collapse

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 2

VEGFA-VEGFR2 Pathway

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 2

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CDC42_HUMAN P60953 CHEMBL6088 Cell Division Control Protein 42 Homolog, Human 2