UCSF

Thymidylate Synthase, Lacca (102 Compounds)

Swissprot:
TYSY_LACCA
Stitch:
TYSY_LACCA
UniProt:
P00469
ChEMBL:
CHEMBL5328
PDB:
1BO7 (DOCK)
1BO8 (DOCK)
1BP0 (DOCK)
1BP6 (DOCK)
1BPJ (DOCK)
1JMF (DOCK)
1JMG (DOCK)
1JMH (DOCK)
1JMI (DOCK)
1LCA (DOCK)
1LCB (DOCK)
1LCE (DOCK)
1NJA (DOCK)
1NJB (DOCK)
1NJC (DOCK)
1NJD (DOCK)
1NJE (DOCK)
1TDA (DOCK)
1TDB (DOCK)
1TDC (DOCK)
1THY (DOCK)
1TSL (DOCK)
1TSM (DOCK)
1TSV (DOCK)
1TSW (DOCK)
1TSX (DOCK)
1TSY (DOCK)
1TSZ (DOCK)
1TVU (DOCK)
1TVV (DOCK)
1TVW (DOCK)
1VZA (DOCK)
1VZB (DOCK)
1VZC (DOCK)
1VZD (DOCK)
1VZE (DOCK)
2G86 (DOCK)
2G89 (DOCK)
2G8A (DOCK)
2G8D (DOCK)
2TDD (DOCK)
2TDM (DOCK)
3BNZ (DOCK)
3BYX (DOCK)
3BZ0 (DOCK)
3C06 (DOCK)
3C0A (DOCK)
3IJZ (DOCK)
3IK0 (DOCK)
3IK1 (DOCK)
4TMS (DOCK)

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 102 2 2 6
Binding ≤ 1μM 33 1 1 4

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
TYSY_CRYNB P0CS13 CHEMBL4665 Thymidylate Synthase, Crynb 14 0 0 0
TYSY_ECOLI P0A884 CHEMBL2555 Thymidylate Synthase, Ecoli 96 7 6 9
TYSY_ENTFA Q834R3 CHEMBL1795144 Thymidylate Synthase, Entfa 4 1 1 4
TYSY_HUMAN P04818 CHEMBL1952 Thymidylate Synthase, Human 443 18 12 14
TYSY_MOUSE P07607 CHEMBL3160 Thymidylate Synthase, Mouse 417 22 13 29
TYSY_MYCTU P67044 CHEMBL1795162 Thymidylate Synthase, Myctu 1 0 1 1
TYSY_RAT P45352 CHEMBL4341 Thymidylate Synthase, Rat 4 1 2 3

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
TYSY-1-B Thymidylate Synthase (cluster #1 Of 1), Bacterial 180 8 8 17
TYSY-1-E Thymidylate Synthase (cluster #1 Of 3), Eukaryotic 764 33 22 36
TYSY-1-O Thymidylate Synthase (cluster #1 Of 1), Other 14 0 0 0
TYSY-2-E Thymidylate Synthase (cluster #2 Of 3), Eukaryotic 1 0 0 0
TYSY-3-E Thymidylate Synthase (cluster #3 Of 3), Eukaryotic 1 1 1 1
Uniprot Swissprot Chembl Description Number Shared
TYSY_ECOLI P0A884 CHEMBL2555 Thymidylate Synthase, Ecoli 23
TYSY_HUMAN P04818 CHEMBL1952 Thymidylate Synthase, Human 22
TYSY_CRYNB P0CS13 CHEMBL4665 Thymidylate Synthase, Crynb 13
DYR_RAT Q920D2 CHEMBL2363 Dihydrofolate Reductase, Rat 9
TYSY_MOUSE P07607 CHEMBL3160 Thymidylate Synthase, Mouse 9
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 7
DYR_LACCA P00381 CHEMBL2902 Dihydrofolate Reductase, Lacca 6
DYR_MOUSE P00375 CHEMBL4564 Dihydrofolate Reductase, Mouse 5
PUR2_MOUSE Q64737 CHEMBL3690 GAR Transformylase, Mouse 3
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 2
TYSY_ENTFA Q834R3 CHEMBL1795144 Thymidylate Synthase, Entfa 2
TYSY_RAT P45352 CHEMBL4341 Thymidylate Synthase, Rat 2
C3SWJ7_ECOLX C3SWJ7 CHEMBL6137 Thymidylate Synthase, Ecolx 1
E2QDN0_ECOLX E2QDN0 CHEMBL1795153 Thymidylate Synthase (EC 2.1.1.45) (TS) (TSase), Ecolx 1
FOLC_MOUSE P48760 CHEMBL2890 Folylpoly-gamma-glutamate Synthetase, Mouse 1
PUR2_HUMAN P22102 CHEMBL3972 GAR Transformylase, Human 1
XDH_BOVIN P80457 CHEMBL3649 Xanthine Dehydrogenase, Bovin 1