UCSF

Mitogen-activated Protein Kinase; ERK1/ERK2 (5 Compounds)

Swissprot:
Z104300
Stitch:
Z104300
UniProt:
Z104300
ChEMBL:
CHEMBL1907606

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 5 1 0 2
Binding ≤ 1μM 1 0 0 1
Functional ≤ 10μM 2 0 0 0

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 4
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 4
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 4
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 4
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 3
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 3
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 3
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 3
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 3
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 3
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 3
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 3
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 3
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 3
PGFRA_RAT P20786 CHEMBL2513 Platelet-derived Growth Factor Receptor Alpha, Rat 3
VGFR2_MOUSE P35918 CHEMBL3337 Vascular Endothelial Growth Factor Receptor 2, Mouse 3
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 2
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 2
FGFR1_MOUSE P16092 CHEMBL3960 Fibroblast Growth Factor Receptor 1, Mouse 2
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 2
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 2
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 2
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 2
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 2
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 2
KC1G1_HUMAN Q9HCP0 CHEMBL2426 Casein Kinase I Gamma 1, Human 2
KC1G2_HUMAN P78368 CHEMBL2543 Casein Kinase I Gamma 2, Human 2
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 2
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 2
Q95J97_RABIT Q95J97 CHEMBL4885 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rabit 2
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 2
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 2
CSK_HUMAN P41240 CHEMBL2634 Tyrosine-protein Kinase CSK, Human 1
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 1
FER_HUMAN P16591 CHEMBL3982 Tyrosine-protein Kinase FER, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 1
IKKB_HUMAN O14920 CHEMBL1991 Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human 1
JAK1_HUMAN P23458 CHEMBL2835 Tyrosine-protein Kinase JAK1, Human 1
JAK1_MOUSE P52332 CHEMBL2968 Tyrosine-protein Kinase JAK1, Mouse 1
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 1
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 1
KAP3_BOVIN P31322 CHEMBL3280 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Bovin 1
KCC2A_HUMAN Q9UQM7 CHEMBL4147 CaM Kinase II Alpha, Human 1
KCC2B_HUMAN Q13554 CHEMBL4121 CaM Kinase II Beta, Human 1
KCC2D_HUMAN Q13557 CHEMBL2801 CaM Kinase II Delta, Human 1
KCC2G_HUMAN Q13555 CHEMBL3829 CaM Kinase II Gamma, Human 1
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 1
M3K1_HUMAN Q13233 CHEMBL3956 Mitogen-activated Protein Kinase Kinase Kinase 1, Human 1
MP2K2_HUMAN P36507 CHEMBL2964 Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human 1
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 1
PGFRB_RAT Q05030 CHEMBL4125 Platelet-derived Growth Factor Receptor Beta, Rat 1
SRC_CHICK P00523 CHEMBL3655 Tyrosine-protein Kinase SRC, Chick 1
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 1
TYK2_HUMAN P29597 CHEMBL3553 Tyrosine-protein Kinase TYK2, Human 1
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 1
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 1
Z80054 Z80054 CHEMBL614058 Caco-2 (Colon Adenocarcinoma Cells) 1
Z80099 Z80099 CHEMBL614561 COLO 205 (Colon Adenocarcinoma Cells) 1
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 1