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    • Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
    UCSF
    ZINC Item Suppliers, Protomers, & Similar Substances

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 4-methyl-N-[[3-(1-piperidylmethyl)phenyl]methyl]pyrimidine-5-carboxamide 4-methyl-N-[[3-(1-piperidylmethy…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.49 8.85 -43.93 2 5 1 59 325.436 5 ↓

    Analogs

    16681121
    16681121

    Draw Identity 99% 90% 80% 70%

    Popular Name: 3-phenyl-N-[4-(1-piperidylmethyl)thiazol-2-yl]imidazole-4-carboxamide 3-phenyl-N-[4-(1-piperidylmethyl…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.40 11.05 -39.73 2 6 1 64 368.486 5 ↓
    Hi High (pH 8-9.5) 3.33 8.12 -14.44 1 6 0 66 367.478 4 ↓
    Hi High (pH 8-9.5) 2.47 7.72 -44.32 0 6 -1 69 366.47 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 3-phenyl-N-[[2-(1-piperidylmethyl)phenyl]methyl]imidazole-4-carboxamide 3-phenyl-N-[[2-(1-piperidylmethy…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.76 0.59 -41.01 2 5 1 51 375.496 6 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 3-phenyl-N-[[2-(pyrrolidin-1-ylmethyl)phenyl]methyl]imidazole-4-carboxamide 3-phenyl-N-[[2-(pyrrolidin-1-ylm…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.26 12.32 -38.05 2 5 1 51 361.469 6 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[(3-methylsulfonylaminophenyl)methyl]-3-phenyl-imidazole-4-carboxamide N-[(3-methylsulfonylaminophenyl)…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.31 5.84 -45.94 1 7 -1 95 369.426 6 ↓
    Lo Low (pH 4.5-6) 1.31 5.78 -17.08 2 7 0 93 370.434 6 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(3-imidazol-1-ylpropyl)-3-phenyl-imidazole-4-carboxamide N-(3-imidazol-1-ylpropyl)-3-phen…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 0.65 9.91 -41.84 2 6 1 66 296.354 6 ↓
    Mid Mid (pH 6-8) 0.65 9.4 -14.91 1 6 0 65 295.346 6 ↓
    Lo Low (pH 4.5-6) 0.65 10.42 -86.65 3 6 2 67 297.362 6 ↓

    Analogs

    8136031
    8136031

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[2-(2-furyl)-2-pyrrolidin-1-yl-ethyl]-3-phenyl-imidazole-4-carboxamide N-[2-(2-furyl)-2-pyrrolidin-1-yl…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.97 10.32 -43.15 2 6 1 65 351.43 6 ↓

    Analogs

    8136034
    8136034

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[2-(2-furyl)-2-pyrrolidin-1-yl-ethyl]-3-phenyl-imidazole-4-carboxamide N-[2-(2-furyl)-2-pyrrolidin-1-yl…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.97 11.27 -40.13 2 6 1 65 351.43 6 ↓

    Analogs

    12506610
    12506610

    Draw Identity 99% 90% 80% 70%

    Popular Name: 3-phenyl-N-[(2R)-2-phenyl-2-pyrrolidin-1-yl-ethyl]imidazole-4-carboxamide 3-phenyl-N-[(2R)-2-phenyl-2-pyrr…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.72 13.05 -41.27 2 5 1 51 361.469 6 ↓

    Analogs

    12506612
    12506612

    Draw Identity 99% 90% 80% 70%

    Popular Name: 3-phenyl-N-[(2S)-2-phenyl-2-pyrrolidin-1-yl-ethyl]imidazole-4-carboxamide 3-phenyl-N-[(2S)-2-phenyl-2-pyrr…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.72 12.18 -43.06 2 5 1 51 361.469 6 ↓

    Analogs

    25081475
    25081475

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[(3R)-1-benzylpyrrolidin-3-yl]-3-phenyl-imidazole-4-carboxamide N-[(3R)-1-benzylpyrrolidin-3-yl]…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.25 11.49 -48.14 2 5 1 51 347.442 5 ↓

    Analogs

    25081475
    25081475

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[(3S)-1-benzylpyrrolidin-3-yl]-3-phenyl-imidazole-4-carboxamide N-[(3S)-1-benzylpyrrolidin-3-yl]…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.25 11.66 -48.11 2 5 1 51 347.442 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: 3-phenyl-N-(2,2,6,6-tetramethyl-4-piperidyl)-imidazole-4-carboxamide 3-phenyl-N-(2,2,6,6-tetramethyl-…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.50 -0.59 -41.27 3 5 1 63 327.452 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: (3-phenylimidazol-4-yl)-[4-(2-pyridyl)piperazin-1-yl]methanone (3-phenylimidazol-4-yl)-[4-(2-py…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.64 9.32 -38.76 1 6 1 56 334.403 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [4-(2-nitrophenyl)sulfonylpiperazin-1-yl]-(3-phenylimidazol-4-yl)methanone [4-(2-nitrophenyl)sulfonylpipera…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.66 10.22 -26 0 10 0 121 441.469 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [4-(3-nitrophenyl)sulfonylpiperazin-1-yl]-(3-phenylimidazol-4-yl)methanone [4-(3-nitrophenyl)sulfonylpipera…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.68 9.17 -18.84 0 10 0 121 441.469 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [4-(4-nitrophenyl)sulfonylpiperazin-1-yl]-(3-phenylimidazol-4-yl)methanone [4-(4-nitrophenyl)sulfonylpipera…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.70 9.19 -18.21 0 10 0 121 441.469 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [4-(2-methyl-5-nitro-phenyl)sulfonylpiperazin-1-yl]-(3-phenylimidazol-4-yl)methanone [4-(2-methyl-5-nitro-phenyl)sulf…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.08 9.55 -19.55 0 10 0 121 455.496 5 ↓

    Analogs

    55669183
    55669183

    Draw Identity 99% 90% 80% 70%

    Popular Name: (3-phenylimidazol-4-yl)-[4-(2-pyrrolidin-1-ylethyl)piperazin-1-yl]methanone (3-phenylimidazol-4-yl)-[4-(2-py…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.27 9.49 -44.48 1 6 1 46 354.478 5 ↓
    Hi High (pH 8-9.5) 1.27 6.97 -9.43 0 6 0 45 353.47 5 ↓
    Lo Low (pH 4.5-6) 1.27 9.96 -93.68 2 6 2 47 355.486 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[1-(2-amino-2-oxo-ethyl)-4-piperidyl]-3-(4-fluorophenyl)imidazole-4-carboxamide N-[1-(2-amino-2-oxo-ethyl)-4-pip…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 0.02 5.55 -47.27 4 7 1 94 346.386 5 ↓
    Hi High (pH 8-9.5) 0.02 3.36 -16.36 3 7 0 93 345.378 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: [3-(4-fluorophenyl)imidazol-4-yl]-[4-(2-pyrrolidin-1-ylethyl)piperazin-1-yl]methanone [3-(4-fluorophenyl)imidazol-4-yl…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.43 9.56 -44.35 1 6 1 46 372.468 5 ↓
    Hi High (pH 8-9.5) 1.43 7.04 -8.7 0 6 0 45 371.46 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: (5-nitro-3H-benzoimidazol-2-yl)sulfanyl-pyrazin-2-yl-methanone (5-nitro-3H-benzoimidazol-2-yl)s…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.29 4.38 -39.85 0 8 -1 116 300.279 4 ↓
    Mid Mid (pH 6-8) 2.29 4.85 -16.01 1 8 0 117 301.287 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[4-(4-nitrophenyl)thiazol-2-yl]pyrazinamide N-[4-(4-nitrophenyl)thiazol-2-yl…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.05 -1.53 -12.92 1 8 0 113 327.325 4 ↓

    Analogs

    36233079
    36233079

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)pyrazine-2-carboxamide hydrochloride N-(4,5,6,7-tetrahydro[1,3]thiazo…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 0.49 1.69 -53.62 3 6 1 84 262.318 2 ↓
    Mid Mid (pH 6-8) 0.49 0.01 -10.09 2 6 0 80 261.31 2 ↓

    Analogs

    16003240
    16003240
    77144851
    77144851
    77144855
    77144855
    77144858
    77144858

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(4-benzyl-7-thia-4,9-diazabicyclo[4.3.0]nona-8,10-dien-8-yl)pyrazine-2-carboxamide N-(4-benzyl-7-thia-4,9-diazabicy…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.14 -2.54 -48.51 2 6 1 72 352.443 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(1-phenylbenzimidazol-2-yl)pyrazine-2-carboxamide N-(1-phenylbenzimidazol-2-yl)pyr…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.69 8.62 -14.33 1 6 0 76 315.336 2 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(1-cyclohexylbenzimidazol-2-yl)pyrazine-2-carboxamide N-(1-cyclohexylbenzimidazol-2-yl…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 3.32 9.01 -12.41 1 6 0 76 321.384 2 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(1-tert-butylbenzimidazol-2-yl)pyrazine-2-carboxamide N-(1-tert-butylbenzimidazol-2-yl…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.60 7.97 -12.81 1 6 0 76 295.346 2 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(4-hydroxy-3-pyridyl)pyrazine-2-carboxamide N-(4-hydroxy-3-pyridyl)pyrazine-…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) -0.46 1.43 -28.91 2 6 0 88 216.2 2 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%


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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.27 3.96 -11.36 1 7 0 101 244.21 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[2-(pyrrolidin-1-ylmethyl)phenyl]pyrazine-2-carboxamide N-[2-(pyrrolidin-1-ylmethyl)phen…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.52 6.26 -40.25 2 5 1 59 283.355 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%


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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.30 3.63 -9.99 1 7 0 101 244.21 3 ↓

    Analogs

    14266291
    14266291

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(2-tert-butyl-1H-benzimidazol-5-yl)pyrazine-2-carboxamide N-(2-tert-butyl-1H-benzimidazol-…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.64 4.22 -12.97 2 6 0 84 295.346 3 ↓
    Lo Low (pH 4.5-6) 2.64 4.53 -30.6 3 6 1 85 296.354 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(4-methyl-2-morpholino-6-quinolyl)pyrazine-2-carboxamide N-(4-methyl-2-morpholino-6-quino…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 2.31 4.03 -32.41 2 7 1 81 350.402 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[4-(3,4-dihydro-2H-pyrrol-5-ylsulfamoyl)phenyl]pyrazine-2-carboxamide N-[4-(3,4-dihydro-2H-pyrrol-5-yl…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 0.76 1.26 -19.27 2 8 0 113 345.384 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%


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    Popular Name:

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.41 -0.2 -10.94 1 7 0 100 262.2 3 ↓

    Analogs

    6321334
    6321334

    Draw Identity 99% 90% 80% 70%


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    Popular Name:

    Find On: PubMed — Wikipedia — Google

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.93 4.02 -9.73 1 7 0 101 278.655 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[(2-morpholino-4-pyridyl)methyl]pyrazine-2-carboxamide N-[(2-morpholino-4-pyridyl)methy…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 0.06 1.57 -41.7 2 7 1 81 300.342 4 ↓
    Mid Mid (pH 6-8) 0.06 1.29 -11.09 1 7 0 80 299.334 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[(2-pyrrolidin-1-yl-4-pyridyl)methyl]pyrazine-2-carboxamide N-[(2-pyrrolidin-1-yl-4-pyridyl)…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 0.62 3.18 -38.76 2 6 1 72 284.343 4 ↓
    Mid Mid (pH 6-8) 0.62 2.98 -10.39 1 6 0 71 283.335 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[[2-(dimethylamino)-4-pyridyl]methyl]pyrazine-2-carboxamide N-[[2-(dimethylamino)-4-pyridyl]…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 0.22 3.22 -37.86 2 6 1 72 258.305 4 ↓
    Mid Mid (pH 6-8) 0.22 2.93 -10.36 1 6 0 71 257.297 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[(2-morpholino-3-pyridyl)methyl]pyrazine-2-carboxamide N-[(2-morpholino-3-pyridyl)methy…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 0.06 1.86 -43.26 2 7 1 81 300.342 4 ↓
    Mid Mid (pH 6-8) 0.06 1.45 -11.42 1 7 0 80 299.334 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[(2-nitrophenyl)methyl]pyrazine-2-carboxamide N-[(2-nitrophenyl)methyl]pyrazin…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 0.97 3.85 -14.59 1 7 0 101 258.237 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[[2-(1-piperidylmethyl)phenyl]methyl]pyrazine-2-carboxamide N-[[2-(1-piperidylmethyl)phenyl]…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.73 -0.51 -34.66 2 5 1 59 311.409 5 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[(6-morpholino-3-pyridyl)methyl]pyrazine-2-carboxamide N-[(6-morpholino-3-pyridyl)methy…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 0.12 -5.79 -38.76 2 7 1 81 300.342 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[[6-(azepan-1-yl)-3-pyridyl]methyl]pyrazine-2-carboxamide N-[[6-(azepan-1-yl)-3-pyridyl]me…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.68 6.14 -35.44 2 6 1 72 312.397 4 ↓
    Mid Mid (pH 6-8) 1.68 5.81 -9.7 1 6 0 71 311.389 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[[6-(1-piperidyl)-3-pyridyl]methyl]pyrazine-2-carboxamide N-[[6-(1-piperidyl)-3-pyridyl]me…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 1.18 5.23 -35.16 2 6 1 72 298.37 4 ↓
    Mid Mid (pH 6-8) 1.18 4.91 -9.81 1 6 0 71 297.362 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-[[6-(dimethylamino)-3-pyridyl]methyl]pyrazine-2-carboxamide N-[[6-(dimethylamino)-3-pyridyl]…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) 0.27 3.19 -37.44 2 6 1 72 258.305 4 ↓
    Mid Mid (pH 6-8) 0.27 2.92 -10.65 1 6 0 71 257.297 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-{4-chloro-3-nitrophenyl}-4-fluorobenzenesulfonamide N-{4-chloro-3-nitrophenyl}-4-flu…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) -0.57 2.89 -36.45 2 6 1 74 232.267 4 ↓
    Mid Mid (pH 6-8) -0.57 2.42 -14.47 1 6 0 73 231.259 4 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(Piperidin-3-ylmethyl)pyrazine-2-carboxamide hydrochloride N-(Piperidin-3-ylmethyl)pyrazine…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) -0.13 1.02 -46.23 3 5 1 71 221.284 3 ↓

    Analogs

    Draw Identity 99% 90% 80% 70%

    Popular Name: N-(Piperidin-3-ylmethyl)pyrazine-2-carboxamide hydrochloride N-(Piperidin-3-ylmethyl)pyrazine…

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    Physical Representations

    Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
    Ref Reference (pH 7) -0.13 1.02 -46.25 3 5 1 71 221.284 3 ↓

    Parameters Provided:

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page.num = 1
catalog.name = ambint
filter.purchasability = purchasable

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