UCSF

Scientific Exchange

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Functional 10μM Targets with Highest Number of Available Compounds (101 in total)

Name (Code) Description Organism Class Size Browse Download (Annotations)
Z50425-3-O Plasmodium falciparum (cluster #3 of 22) Other 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50597-1-O Rattus norvegicus (cluster #1 of 12) Other 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRPA1-4-E Transient receptor potential cation channel subfamily A member 1 (cluster #4 of 6) Eukaryotes 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50459-1-O Leishmania donovani (cluster #1 of 8) Other 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50594-1-O Mus musculus (cluster #1 of 9) Other 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50607-1-O Human immunodeficiency virus 1 (cluster #1 of 10) Other 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ECR-1-E Ecdysone receptor (cluster #1 of 1) Eukaryotes 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50587-1-O Homo sapiens (cluster #1 of 9) Other 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50606-2-O Hepatitis B virus (cluster #2 of 3) Other 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM1-1-E Muscarinic acetylcholine receptor M1 (cluster #1 of 3) Eukaryotes 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM3-1-E Muscarinic acetylcholine receptor M3 (cluster #1 of 3) Eukaryotes 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ERR3-2-E Estrogen-related receptor gamma (cluster #2 of 2) Eukaryotes 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ESR2-1-E Estrogen receptor beta (cluster #1 of 2) Eukaryotes 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
LPAR2-4-E Lysophosphatidic acid receptor Edg-4 (cluster #4 of 4) Eukaryotes 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
LPAR3-3-E Lysophosphatidic acid receptor Edg-7 (cluster #3 of 3) Eukaryotes 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH1-1-E Cyclooxygenase-1 (cluster #1 of 2) Eukaryotes 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH2-1-E Cyclooxygenase-2 (cluster #1 of 1) Eukaryotes 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4-1-E Serotonin transporter (cluster #1 of 1) Eukaryotes 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
THAS-1-E Thromboxane-A synthase (cluster #1 of 1) Eukaryotes 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
TNR1A-1-E Tumor necrosis factor receptor R1 (cluster #1 of 1) Eukaryotes 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100405-1-O MV4-11 (Myeloid leukemia cells) (cluster #1 of 1) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50466-4-O Trypanosoma cruzi (cluster #4 of 8) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50468-2-O Giardia intestinalis (cluster #2 of 4) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50512-1-O Cavia porcellus (cluster #1 of 7) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50587-7-O Homo sapiens (cluster #7 of 9) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50597-11-O Rattus norvegicus (cluster #11 of 12) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50606-1-O Hepatitis B virus (cluster #1 of 3) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50609-1-O Simian immunodeficiency virus (cluster #1 of 2) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50643-2-O Hepatitis C virus (cluster #2 of 5) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50725-1-O Trypanosoma brucei rhodesiense (cluster #1 of 7) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80224-1-O MCF7 (Breast carcinoma cells) (cluster #1 of 14) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80874-3-O CEM (T-cell leukemia) (cluster #3 of 7) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81247-2-O HeLa (Cervical adenocarcinoma cells) (cluster #2 of 9) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81331-6-O SW-620 (Colon adenocarcinoma cells) (cluster #6 of 6) Other 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA1D-1-E Alpha-1d adrenergic receptor (cluster #1 of 4) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ANDR-3-E Androgen Receptor (cluster #3 of 3) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CAH1-1-E Carbonic anhydrase I (cluster #1 of 3) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CAH2-2-E Carbonic anhydrase II (cluster #2 of 2) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CAH4-2-E Carbonic anhydrase IV (cluster #2 of 2) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD4-1-E Dopamine D4 receptor (cluster #1 of 1) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH1-1-E Histamine H1 receptor (cluster #1 of 2) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LOX5-1-E Arachidonate 5-lipoxygenase (cluster #1 of 7) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LOX5-3-E Arachidonate 5-lipoxygenase (cluster #3 of 7) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDE2-1-E Glutamate [NMDA] receptor subunit epsilon 2 (cluster #1 of 2) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDZ1-2-E Glutamate (NMDA) receptor subunit zeta 1 (cluster #2 of 3) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARA-1-E Peroxisome proliferator-activated receptor alpha (cluster #1 of 2) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARG-1-E Peroxisome proliferator-activated receptor gamma (cluster #1 of 2) Eukaryotes 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100081-3-O PBMC (Peripheral blood mononuclear cells) (cluster #3 of 4) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100748-1-O Neutrophils (cluster #1 of 2) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z101900-1-O Measles virus genotype A (cluster #1 of 1) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z101901-1-O Measles virus genotype D6 (cluster #1 of 1) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z101902-1-O Measles virus genotype D7 (cluster #1 of 1) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z102213-1-O Blood (cluster #1 of 2) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z102306-1-O Aorta (cluster #1 of 6) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50028-1-O Streptococcus pneumoniae (cluster #1 of 2) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50185-3-O Staphylococcus aureus (cluster #3 of 4) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50418-5-O Trypanosoma brucei (cluster #5 of 6) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50420-7-O Trypanosoma brucei brucei (cluster #7 of 7) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50422-3-O Entamoeba histolytica (cluster #3 of 5) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50422-5-O Entamoeba histolytica (cluster #5 of 5) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50425-11-O Plasmodium falciparum (cluster #11 of 22) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50425-15-O Plasmodium falciparum (cluster #15 of 22) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50425-7-O Plasmodium falciparum (cluster #7 of 22) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50459-2-O Leishmania donovani (cluster #2 of 8) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50459-5-O Leishmania donovani (cluster #5 of 8) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50466-1-O Trypanosoma cruzi (cluster #1 of 8) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50466-7-O Trypanosoma cruzi (cluster #7 of 8) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50472-3-O Toxoplasma gondii (cluster #3 of 4) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50512-6-O Cavia porcellus (cluster #6 of 7) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50587-3-O Homo sapiens (cluster #3 of 9) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50587-4-O Homo sapiens (cluster #4 of 9) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50592-3-O Oryctolagus cuniculus (cluster #3 of 8) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50594-6-O Mus musculus (cluster #6 of 9) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50597-3-O Rattus norvegicus (cluster #3 of 12) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50600-2-O Vaccinia virus (cluster #2 of 2) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50602-2-O Human herpesvirus 1 (cluster #2 of 5) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50650-1-O Measles virus (cluster #1 of 1) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50665-1-O Enterovirus (cluster #1 of 1) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50666-1-O Coxsackievirus (cluster #1 of 1) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50731-1-O Echovirus (cluster #1 of 1) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80120-1-O DLD-1 (Colon adenocarcinoma cells) (cluster #1 of 5) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80186-2-O K562 (Erythroleukemia cells) (cluster #2 of 11) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80243-1-O MDA-MB-453 (Breast adenocarcinoma cells) (cluster #1 of 1) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80356-1-O OVCAR-5 (Ovarian adenocarcinoma cells) (cluster #1 of 2) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80387-1-O PC-12 (Adrenal phaeochromacytoma cells) (cluster #1 of 3) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80390-1-O PC-3 (Prostate carcinoma cells) (cluster #1 of 10) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80418-2-O RAW264.7 (Monocytic-macrophage leukemia cells) (cluster #2 of 9) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80491-3-O SK-N-MC (Neuroepithelioma cells) (cluster #3 of 4) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80526-1-O SW480 (Colon adenocarcinoma cells) (cluster #1 of 6) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80548-1-O THP-1 (Acute monocytic leukemia cells) (cluster #1 of 5) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80583-1-O Vero (Kidney cells) (cluster #1 of 7) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80608-1-O ZR-75-1 (Breast carcinoma cells) (cluster #1 of 4) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80712-2-O T47D (Breast carcinoma cells) (cluster #2 of 7) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80945-2-O HEp-2 (Laryngeal carcinoma cells) (cluster #2 of 4) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81020-6-O HepG2 (Hepatoblastoma cells) (cluster #6 of 8) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81024-5-O NCI-H460 (Non-small cell lung carcinoma) (cluster #5 of 8) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81115-1-O KB (Squamous cell carcinoma) (cluster #1 of 6) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81247-1-O HeLa (Cervical adenocarcinoma cells) (cluster #1 of 9) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81247-7-O HeLa (Cervical adenocarcinoma cells) (cluster #7 of 9) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81267-1-O Mononuclear cell line (cluster #1 of 1) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81335-2-O HCT-15 (Colon adenocarcinoma cells) (cluster #2 of 5) Other 1 Annotations Catalogs SMILES SDF Mol2 Flexibase