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ZINC Item

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36636005

Analogs

36636006

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Popular Name: (2R)-2-[(4-fluorophenyl)methyl]-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-one (2R)-2-[(4-fluorophenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.05	6.29	-6.99	0	3	0	33	264.325	2	↓ MOL2 SDF SMILES Flexibase

36636006

Analogs

36636005

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Popular Name: (2S)-2-[(4-fluorophenyl)methyl]-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-one (2S)-2-[(4-fluorophenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.05	6.29	-7.01	0	3	0	33	264.325	2	↓ MOL2 SDF SMILES Flexibase

36636009

Analogs

36636010

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Popular Name: (2R)-2-[(4-chlorophenyl)methyl]-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-one (2R)-2-[(4-chlorophenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.56	6.74	-6.39	0	3	0	33	280.78	2	↓ MOL2 SDF SMILES Flexibase

36636010

Analogs

36636009

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Popular Name: (2S)-2-[(4-chlorophenyl)methyl]-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-one (2S)-2-[(4-chlorophenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.56	6.75	-6.37	0	3	0	33	280.78	2	↓ MOL2 SDF SMILES Flexibase

64980825

Analogs

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Popular Name: 2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]-N-phenyl-acetamide 2-[(2R)-3-oxo-6,7-dihydro-5H-thi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.15	4.55	-10.98	1	5	0	62	289.36	3	↓ MOL2 SDF SMILES Flexibase

64980826

Analogs

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Popular Name: 2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]-N-phenyl-acetamide 2-[(2S)-3-oxo-6,7-dihydro-5H-thi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.15	4.55	-10.95	1	5	0	62	289.36	3	↓ MOL2 SDF SMILES Flexibase

64980827

Analogs

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Popular Name: N-(2-fluorophenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-fluorophenyl)-2-[(2R)-3-oxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.27	4.67	-9.72	1	5	0	62	307.35	3	↓ MOL2 SDF SMILES Flexibase

64980828

Analogs

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Popular Name: N-(2-fluorophenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-fluorophenyl)-2-[(2S)-3-oxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.27	4.67	-9.57	1	5	0	62	307.35	3	↓ MOL2 SDF SMILES Flexibase

64980829

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.46	5.55	-10.9	1	7	0	88	347.396	5	↓ MOL2 SDF SMILES Flexibase

64980830

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.46	5.55	-10.64	1	7	0	88	347.396	5	↓ MOL2 SDF SMILES Flexibase

64980831

Analogs

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Popular Name: N-(2-nitrophenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-nitrophenyl)-2-[(2R)-3-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.06	5.6	-12.14	1	8	0	108	334.357	4	↓ MOL2 SDF SMILES Flexibase

64980832

Analogs

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Popular Name: N-(2-nitrophenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-nitrophenyl)-2-[(2S)-3-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.06	5.6	-11.6	1	8	0	108	334.357	4	↓ MOL2 SDF SMILES Flexibase

64980833

Analogs

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Popular Name: 2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]-N-[2-(trifluoromethyl)phenyl]acetamide 2-[(2R)-3-oxo-6,7-dihydro-5H-thi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.00	5.8	-9.27	1	5	0	62	357.357	4	↓ MOL2 SDF SMILES Flexibase

64980834

Analogs

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Popular Name: 2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]-N-[2-(trifluoromethyl)phenyl]acetamide 2-[(2S)-3-oxo-6,7-dihydro-5H-thi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.00	5.8	-9.05	1	5	0	62	357.357	4	↓ MOL2 SDF SMILES Flexibase

64980835

Analogs

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Popular Name: N-(o-tolyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(o-tolyl)-2-[(2R)-3-oxo-6,7-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.55	5.45	-10.95	1	5	0	62	303.387	3	↓ MOL2 SDF SMILES Flexibase

64980836

Analogs

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Popular Name: N-(o-tolyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(o-tolyl)-2-[(2S)-3-oxo-6,7-di…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.55	5.45	-10.96	1	5	0	62	303.387	3	↓ MOL2 SDF SMILES Flexibase

64980837

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.83	6.48	-10.62	1	7	0	88	361.423	6	↓ MOL2 SDF SMILES Flexibase

64980838

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.83	6.48	-10.29	1	7	0	88	361.423	6	↓ MOL2 SDF SMILES Flexibase

64980839

Analogs

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Popular Name: N-(2-methoxyphenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-methoxyphenyl)-2-[(2R)-3-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.16	3.98	-10.65	1	6	0	71	319.386	4	↓ MOL2 SDF SMILES Flexibase

64980840

Analogs

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Popular Name: N-(2-methoxyphenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-methoxyphenyl)-2-[(2S)-3-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.16	3.98	-10.53	1	6	0	71	319.386	4	↓ MOL2 SDF SMILES Flexibase

64980841

Analogs

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Popular Name: N-(2-ethylphenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-ethylphenyl)-2-[(2R)-3-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.02	6.23	-10.42	1	5	0	62	317.414	4	↓ MOL2 SDF SMILES Flexibase

64980842

Analogs

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Popular Name: N-(2-ethylphenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-ethylphenyl)-2-[(2S)-3-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.02	6.23	-10.4	1	5	0	62	317.414	4	↓ MOL2 SDF SMILES Flexibase

64980843

Analogs

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Popular Name: N-(2-chlorophenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-chlorophenyl)-2-[(2R)-3-oxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.78	5.17	-9.21	1	5	0	62	323.805	3	↓ MOL2 SDF SMILES Flexibase

64980844

Analogs

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Popular Name: N-(2-chlorophenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-chlorophenyl)-2-[(2S)-3-oxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.78	5.17	-9.09	1	5	0	62	323.805	3	↓ MOL2 SDF SMILES Flexibase

64980845

Analogs

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Popular Name: N-(2-cyanophenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-cyanophenyl)-2-[(2R)-3-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.86	5	-10.89	1	6	0	86	314.37	3	↓ MOL2 SDF SMILES Flexibase

64980846

Analogs

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Popular Name: N-(2-cyanophenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(2-cyanophenyl)-2-[(2S)-3-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.86	5	-10.64	1	6	0	86	314.37	3	↓ MOL2 SDF SMILES Flexibase

64980847

Analogs

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Popular Name: 2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide 2-[(2R)-3-oxo-6,7-dihydro-5H-thi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.12	4.34	-10.93	1	6	0	71	373.356	5	↓ MOL2 SDF SMILES Flexibase

64980848

Analogs

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Popular Name: 2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide 2-[(2S)-3-oxo-6,7-dihydro-5H-thi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.12	4.34	-10.83	1	6	0	71	373.356	5	↓ MOL2 SDF SMILES Flexibase

64980849

Analogs

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Popular Name: N-(4-nitrophenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-nitrophenyl)-2-[(2R)-3-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.11	5.27	-15.38	1	8	0	108	334.357	4	↓ MOL2 SDF SMILES Flexibase

64980850

Analogs

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Popular Name: N-(4-nitrophenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-nitrophenyl)-2-[(2S)-3-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.11	5.27	-15.29	1	8	0	108	334.357	4	↓ MOL2 SDF SMILES Flexibase

64980851

Analogs

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Popular Name: N-(4-chlorophenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-chlorophenyl)-2-[(2R)-3-oxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.83	5.07	-11	1	5	0	62	323.805	3	↓ MOL2 SDF SMILES Flexibase

64980852

Analogs

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Popular Name: N-(4-chlorophenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-chlorophenyl)-2-[(2S)-3-oxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.83	5.07	-10.99	1	5	0	62	323.805	3	↓ MOL2 SDF SMILES Flexibase

64980853

Analogs

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Popular Name: N-(4-morpholinophenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-morpholinophenyl)-2-[(2R)-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.10	4.52	-12.74	1	7	0	74	374.466	4	↓ MOL2 SDF SMILES Flexibase

64980854

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Popular Name: N-(4-morpholinophenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-morpholinophenyl)-2-[(2S)-3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.10	4.52	-12.73	1	7	0	74	374.466	4	↓ MOL2 SDF SMILES Flexibase

64980855

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Popular Name: [4-[[2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetyl]amino]phenyl] [4-[[2-[(2R)-3-oxo-6,7-dihydro-5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.71	5.8	-16.4	1	7	0	88	347.396	5	↓ MOL2 SDF SMILES Flexibase

64980856

Analogs

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Popular Name: [4-[[2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetyl]amino]phenyl] [4-[[2-[(2S)-3-oxo-6,7-dihydro-5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.71	5.8	-16.44	1	7	0	88	347.396	5	↓ MOL2 SDF SMILES Flexibase

64980857

Analogs

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Popular Name: 2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]-N-(p-tolyl)acetamide 2-[(2R)-3-oxo-6,7-dihydro-5H-thi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.60	5.23	-11.01	1	5	0	62	303.387	3	↓ MOL2 SDF SMILES Flexibase

64980858

Analogs

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Popular Name: 2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]-N-(p-tolyl)acetamide 2-[(2S)-3-oxo-6,7-dihydro-5H-thi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.60	5.23	-10.99	1	5	0	62	303.387	3	↓ MOL2 SDF SMILES Flexibase

64980859

Analogs

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Popular Name: N-(4-fluorophenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-fluorophenyl)-2-[(2R)-3-oxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.32	4.62	-11.64	1	5	0	62	307.35	3	↓ MOL2 SDF SMILES Flexibase

64980860

Analogs

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Popular Name: N-(4-fluorophenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-fluorophenyl)-2-[(2S)-3-oxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.32	4.62	-11.64	1	5	0	62	307.35	3	↓ MOL2 SDF SMILES Flexibase

64980861

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Popular Name: N-(4-ethylphenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-ethylphenyl)-2-[(2R)-3-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.07	5.99	-10.85	1	5	0	62	317.414	4	↓ MOL2 SDF SMILES Flexibase

64980862

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Popular Name: N-(4-ethylphenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-ethylphenyl)-2-[(2S)-3-oxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.07	5.99	-10.84	1	5	0	62	317.414	4	↓ MOL2 SDF SMILES Flexibase

64980863

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Popular Name: 2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]-N-(4-pyrrolidin-1-ylphenyl)acetamide 2-[(2R)-3-oxo-6,7-dihydro-5H-thi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.66	6.25	-11.83	1	6	0	65	358.467	4	↓ MOL2 SDF SMILES Flexibase

64980864

Analogs

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Popular Name: 2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]-N-(4-pyrrolidin-1-ylphenyl)acetamide 2-[(2S)-3-oxo-6,7-dihydro-5H-thi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.66	6.25	-11.87	1	6	0	65	358.467	4	↓ MOL2 SDF SMILES Flexibase

64980865

Analogs

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Popular Name: N-[4-(difluoromethoxy)phenyl]-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-[4-(difluoromethoxy)phenyl]-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.77	4.13	-13.24	1	6	0	71	355.366	5	↓ MOL2 SDF SMILES Flexibase

64980866

Analogs

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Popular Name: N-[4-(difluoromethoxy)phenyl]-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-[4-(difluoromethoxy)phenyl]-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.77	4.13	-13.14	1	6	0	71	355.366	5	↓ MOL2 SDF SMILES Flexibase

64980867

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Popular Name: N-(4-dimethylaminophenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-dimethylaminophenyl)-2-[(2R…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.26	4.98	-11.94	1	6	0	65	332.429	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	1.26	5.72	-25.1	2	6	0	66	333.437	4	↓ MOL2 SDF SMILES Flexibase

64980868

Analogs

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Popular Name: N-(4-dimethylaminophenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-dimethylaminophenyl)-2-[(2S…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.26	4.98	-11.91	1	6	0	65	332.429	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	1.26	5.72	-25.16	2	6	0	66	333.437	4	↓ MOL2 SDF SMILES Flexibase

64980869

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Popular Name: N-(4-hydroxyphenyl)-2-[(2R)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-hydroxyphenyl)-2-[(2R)-3-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.68	1.69	-12.86	2	6	0	82	305.359	3	↓ MOL2 SDF SMILES Flexibase

64980870

Analogs

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Popular Name: N-(4-hydroxyphenyl)-2-[(2S)-3-oxo-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-2-yl]acetamide N-(4-hydroxyphenyl)-2-[(2S)-3-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.68	1.69	-12.84	2	6	0	82	305.359	3	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
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Structural Results Found: (before additional filtering)

SQL Query Was

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