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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

4248141
4248141

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Popular Name: N-[5-[(4-sulfamoylphenyl)methyl]thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(4-sulfamoylphenyl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.64 0.3 -47.99 5 8 1 128 366.448 5 ↓
Hi High (pH 8-9.5) 0.64 -0.76 -19.34 4 8 0 127 365.44 5 ↓
Hi High (pH 8-9.5) 0.82 -1.42 -37.54 4 8 0 134 365.44 5 ↓

Analogs

4248143
4248143
4248141
4248141

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Popular Name: N-[4-methyl-5-[(4-sulfamoylphenyl)methyl]thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[4-methyl-5-[(4-sulfamoylpheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.86 0.8 -48.67 5 8 1 128 380.475 5 ↓
Hi High (pH 8-9.5) 0.86 -0.26 -18.46 4 8 0 127 379.467 5 ↓
Hi High (pH 8-9.5) 1.04 -0.91 -36.53 4 8 0 134 379.467 5 ↓

Analogs

4248139
4248139

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Popular Name: N-(5-benzyl-4-methyl-thiazol-2-yl)-4,5-dihydro-1H-imidazole-2-carboxamide N-(5-benzyl-4-methyl-thiazol-2-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.16 5.83 -39.08 3 5 1 68 301.395 4 ↓
Hi High (pH 8-9.5) 2.16 4.78 -10.88 2 5 0 66 300.387 4 ↓
Hi High (pH 8-9.5) 2.35 4.12 -30.66 2 5 0 74 300.387 4 ↓

Analogs

4248144
4248144

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Popular Name: N-[4-methyl-5-[[3-(trifluoromethyl)phenyl]methyl]thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamid N-[4-methyl-5-[[3-(trifluorometh…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.03 6.85 -40.22 3 5 1 68 369.392 5 ↓
Hi High (pH 8-9.5) 3.03 5.8 -12.22 2 5 0 66 368.384 5 ↓
Hi High (pH 8-9.5) 3.22 5.14 -31.16 2 5 0 74 368.384 5 ↓

Analogs

4248139
4248139

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Popular Name: N-[4-methyl-5-[(3-nitrophenyl)methyl]thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[4-methyl-5-[(3-nitrophenyl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 6.55 -44.34 3 8 1 114 346.392 5 ↓
Hi High (pH 8-9.5) 2.10 5.5 -16.32 2 8 0 112 345.384 5 ↓
Hi High (pH 8-9.5) 2.28 4.84 -34.5 2 8 0 120 345.384 5 ↓

Analogs

4248139
4248139

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Popular Name: N-[4-methyl-5-[(4-nitrophenyl)methyl]thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[4-methyl-5-[(4-nitrophenyl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 6.55 -46.35 3 8 1 114 346.392 5 ↓
Hi High (pH 8-9.5) 2.12 5.5 -16.62 2 8 0 112 345.384 5 ↓
Hi High (pH 8-9.5) 2.31 4.84 -33.29 2 8 0 120 345.384 5 ↓

Analogs

4248145
4248145

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Popular Name: N-[5-[(4-fluorophenyl)methyl]-4-methyl-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(4-fluorophenyl)methyl]-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.33 5.9 -41.06 3 5 1 68 319.385 4 ↓
Hi High (pH 8-9.5) 2.33 4.85 -12.33 2 5 0 66 318.377 4 ↓
Hi High (pH 8-9.5) 2.51 4.19 -30.8 2 5 0 74 318.377 4 ↓

Analogs

4248143
4248143
4248142
4248142

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Popular Name: N-[5-[(4-methoxyphenyl)methyl]-4-methyl-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(4-methoxyphenyl)methyl]-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.22 5.13 -41.14 3 6 1 77 331.421 5 ↓
Hi High (pH 8-9.5) 2.22 4.07 -12.73 2 6 0 76 330.413 5 ↓
Hi High (pH 8-9.5) 2.40 3.42 -32.04 2 6 0 84 330.413 5 ↓

Analogs

12292286
12292286
5001107
5001107

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Popular Name: N-[5-[(4-chlorophenyl)methyl]-4-methyl-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(4-chlorophenyl)methyl]-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.84 6.36 -40.26 3 5 1 68 335.84 4 ↓
Hi High (pH 8-9.5) 2.84 5.3 -11.58 2 5 0 66 334.832 4 ↓
Hi High (pH 8-9.5) 3.03 4.64 -30.22 2 5 0 74 334.832 4 ↓

Analogs

5001107
5001107
547049
547049

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Popular Name: N-[5-[(3-chlorophenyl)methyl]-4-methyl-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(3-chlorophenyl)methyl]-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.82 6.35 -39.36 3 5 1 68 335.84 4 ↓
Hi High (pH 8-9.5) 2.82 5.29 -11.32 2 5 0 66 334.832 4 ↓
Hi High (pH 8-9.5) 3.00 4.63 -30.55 2 5 0 74 334.832 4 ↓

Analogs

2706868
2706868

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Popular Name: N-[5-[(2-chlorophenyl)methyl]-4-methyl-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(2-chlorophenyl)methyl]-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.79 6.21 -38.2 3 5 1 68 335.84 4 ↓
Hi High (pH 8-9.5) 2.79 5.15 -10.94 2 5 0 66 334.832 4 ↓
Hi High (pH 8-9.5) 2.98 4.5 -31.35 2 5 0 74 334.832 4 ↓

Analogs

5001107
5001107
547049
547049

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Popular Name: N-[5-[(3,4-dichlorophenyl)methyl]-4-methyl-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(3,4-dichlorophenyl)methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 6.8 -40.92 3 5 1 68 370.285 4 ↓
Hi High (pH 8-9.5) 3.45 5.75 -12.42 2 5 0 66 369.277 4 ↓
Hi High (pH 8-9.5) 3.63 5.09 -30.56 2 5 0 74 369.277 4 ↓

Analogs

40143141
40143141
4619725
4619725
6505457
6505457

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Popular Name: N-[5-[(2,5-dichlorophenyl)methyl]-4-methyl-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(2,5-dichlorophenyl)methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 6.72 -38.45 3 5 1 68 370.285 4 ↓
Hi High (pH 8-9.5) 3.45 5.66 -10.42 2 5 0 66 369.277 4 ↓
Hi High (pH 8-9.5) 3.63 5.01 -30.05 2 5 0 74 369.277 4 ↓

Analogs

4865497
4865497
4248139
4248139

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Popular Name: N-[5-[(3-bromophenyl)methyl]-4-methyl-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(3-bromophenyl)methyl]-4-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.95 6.45 -39.3 3 5 1 68 380.291 4 ↓
Hi High (pH 8-9.5) 2.95 5.39 -11.31 2 5 0 66 379.283 4 ↓
Hi High (pH 8-9.5) 3.13 4.74 -30.5 2 5 0 74 379.283 4 ↓

Analogs

4865497
4865497

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Popular Name: N-[5-[(4-bromophenyl)methyl]-4-methyl-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(4-bromophenyl)methyl]-4-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.97 6.46 -40.23 3 5 1 68 380.291 4 ↓
Hi High (pH 8-9.5) 2.97 5.41 -11.55 2 5 0 66 379.283 4 ↓
Hi High (pH 8-9.5) 3.16 4.75 -30.13 2 5 0 74 379.283 4 ↓

Analogs

4248144
4248144

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Popular Name: N-[5-[[2-chloro-5-(trifluoromethyl)phenyl]methyl]-4-methyl-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2- N-[5-[[2-chloro-5-(trifluorometh…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.66 7.14 -39.39 3 5 1 68 403.837 5 ↓
Hi High (pH 8-9.5) 3.66 6.09 -11 2 5 0 66 402.829 5 ↓
Hi High (pH 8-9.5) 3.85 5.43 -30.41 2 5 0 74 402.829 5 ↓

Analogs

40143141
40143141
547049
547049

Draw Identity 99% 90% 80% 70%

Popular Name: N-[5-[(4-bromo-3-chloro-phenyl)methyl]thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(4-bromo-3-chloro-phenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.36 6.4 -41.96 3 5 1 68 400.709 4 ↓
Hi High (pH 8-9.5) 3.36 5.35 -12.41 2 5 0 66 399.701 4 ↓
Hi High (pH 8-9.5) 3.54 4.69 -30.19 2 5 0 74 399.701 4 ↓

Analogs

5001107
5001107
547049
547049

Draw Identity 99% 90% 80% 70%

Popular Name: N-[5-[(4-bromo-3-chloro-phenyl)methyl]-4-methyl-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-[(4-bromo-3-chloro-phenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.58 6.91 -40.84 3 5 1 68 414.736 4 ↓
Hi High (pH 8-9.5) 3.58 5.85 -12.34 2 5 0 66 413.728 4 ↓
Hi High (pH 8-9.5) 3.76 5.19 -30.42 2 5 0 74 413.728 4 ↓

Analogs

6453165
6453165
6503813
6503813
6505457
6505457
6505721
6505721
36639389
36639389

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Popular Name: N-[5-(3-chloro-4-methylbenzyl)-1,3-thiazol-2-yl]-4,5-dihydro-1H-imidazole-2-carboxamide N-[5-(3-chloro-4-methylbenzyl)-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.00 -4.37 -40.25 3 5 1 67 335.84 4 ↓

Parameters Provided:

ring.id = 104826
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 104826 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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