ZINC 12

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ZINC Item

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50445479

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(3-methoxyphenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.60	3.03	-17.37	3	6	0	86	273.292	4	↓ MOL2 SDF SMILES Flexibase

50445480

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(2-fluorophenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.68	3.86	-15.59	3	5	0	77	261.256	3	↓ MOL2 SDF SMILES Flexibase

50445482

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(3-chlorophenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.22	4.25	-15.77	3	5	0	77	277.711	3	↓ MOL2 SDF SMILES Flexibase

50445484

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(2-chlorophenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.19	4.35	-14.96	3	5	0	77	277.711	3	↓ MOL2 SDF SMILES Flexibase

50445486

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(2-bromophenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.32	4.49	-14.79	3	5	0	77	322.162	3	↓ MOL2 SDF SMILES Flexibase

50445488

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(4-fluorophenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.73	3.81	-17.22	3	5	0	77	261.256	3	↓ MOL2 SDF SMILES Flexibase

50445490

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(3-fluorophenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.70	3.8	-16.22	3	5	0	77	261.256	3	↓ MOL2 SDF SMILES Flexibase

50445556

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-phenyl-acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-ph…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.56	3.73	-16.72	3	5	0	77	243.266	3	↓ MOL2 SDF SMILES Flexibase

50445560

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(4-chlorophenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.24	4.26	-16.66	3	5	0	77	277.711	3	↓ MOL2 SDF SMILES Flexibase

50445562

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(4-methoxyphenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.62	3.02	-17.62	3	6	0	86	273.292	4	↓ MOL2 SDF SMILES Flexibase

50445564

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(2-methoxyphenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.57	3.17	-16.69	3	6	0	86	273.292	4	↓ MOL2 SDF SMILES Flexibase

50445566

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(4-bromophenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.37	4.37	-16.53	3	5	0	77	322.162	3	↓ MOL2 SDF SMILES Flexibase

50445568

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(3-bromophenyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.35	4.36	-15.7	3	5	0	77	322.162	3	↓ MOL2 SDF SMILES Flexibase

50445570

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(p-tolyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.01	4.41	-16.72	3	5	0	77	257.293	3	↓ MOL2 SDF SMILES Flexibase

50445571

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(m-tolyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.99	4.41	-16.66	3	5	0	77	257.293	3	↓ MOL2 SDF SMILES Flexibase

50445573

Analogs

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Popular Name: 2-(3-amino-2-oxo-1-pyridyl)-N-(o-tolyl)acetamide 2-(3-amino-2-oxo-1-pyridyl)-N-(o…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.96	4.63	-17.34	3	5	0	77	257.293	3	↓ MOL2 SDF SMILES Flexibase

71505477

Analogs

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Popular Name: 2-(2-methyl-6-oxo-1-pyridyl)-N-(4-nitrophenyl)acetamide 2-(2-methyl-6-oxo-1-pyridyl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.25	6.88	-22	1	7	0	97	287.275	4	↓ MOL2 SDF SMILES Flexibase

71505547

Analogs

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Popular Name: 2-(2-methyl-6-oxo-1-pyridyl)-N-(3-nitrophenyl)acetamide 2-(2-methyl-6-oxo-1-pyridyl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.22	6.87	-28.38	1	7	0	97	287.275	4	↓ MOL2 SDF SMILES Flexibase

71513387

Analogs

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Popular Name: N-(2-chlorophenyl)-2-(4-methyl-2-oxo-1-pyridyl)acetamide N-(2-chlorophenyl)-2-(4-methyl-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.16	7.1	-16.78	1	4	0	51	276.723	3	↓ MOL2 SDF SMILES Flexibase

71513389

Analogs

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Popular Name: N-(4-chlorophenyl)-2-(4-methyl-2-oxo-1-pyridyl)acetamide N-(4-chlorophenyl)-2-(4-methyl-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.21	6.99	-19.28	1	4	0	51	276.723	3	↓ MOL2 SDF SMILES Flexibase

71513393

Analogs

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Popular Name: N-(4-chloro-2-methyl-phenyl)-2-(4-methyl-2-oxo-1-pyridyl)acetamide N-(4-chloro-2-methyl-phenyl)-2-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.58	7.83	-18.48	1	4	0	51	290.75	3	↓ MOL2 SDF SMILES Flexibase

71513401

Analogs

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Popular Name: 2-(4-methyl-2-oxo-1-pyridyl)-N-[3-(trifluoromethyl)phenyl]acetamide 2-(4-methyl-2-oxo-1-pyridyl)-N-[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.40	7.48	-22.89	1	4	0	51	310.275	4	↓ MOL2 SDF SMILES Flexibase

71513410

Analogs

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Popular Name: N-(2,5-dimethoxyphenyl)-2-(4-methyl-2-oxo-1-pyridyl)acetamide N-(2,5-dimethoxyphenyl)-2-(4-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.57	5.16	-21.94	1	6	0	70	302.33	5	↓ MOL2 SDF SMILES Flexibase

71513418

Analogs

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Popular Name: 2-(4-methyl-2-oxo-1-pyridyl)-N-[2-(trifluoromethyl)phenyl]acetamide 2-(4-methyl-2-oxo-1-pyridyl)-N-[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.38	7.71	-17.49	1	4	0	51	310.275	4	↓ MOL2 SDF SMILES Flexibase

71513435

Analogs

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Popular Name: 2-(4-methyl-2-oxo-1-pyridyl)-N-(4-nitrophenyl)acetamide 2-(4-methyl-2-oxo-1-pyridyl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.49	7.18	-23.09	1	7	0	97	287.275	4	↓ MOL2 SDF SMILES Flexibase

71513494

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.70	7.13	-23.97	1	6	0	77	300.314	5	↓ MOL2 SDF SMILES Flexibase

71513499

Analogs

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Popular Name: N-(2-methoxy-5-methyl-phenyl)-2-(4-methyl-2-oxo-1-pyridyl)acetamide N-(2-methoxy-5-methyl-phenyl)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	6.56	-19.1	1	5	0	60	286.331	4	↓ MOL2 SDF SMILES Flexibase

71513506

Analogs

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Popular Name: 2-(4-methyl-2-oxo-1-pyridyl)-N-(3-nitrophenyl)acetamide 2-(4-methyl-2-oxo-1-pyridyl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.46	7.17	-29.28	1	7	0	97	287.275	4	↓ MOL2 SDF SMILES Flexibase

71515066

Analogs

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Popular Name: 2-(5-bromo-2-oxo-1-pyridyl)-N-(2-methyl-5-nitro-phenyl)acetamide 2-(5-bromo-2-oxo-1-pyridyl)-N-(2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.55	8	-24.82	1	7	0	97	366.171	4	↓ MOL2 SDF SMILES Flexibase

71515067

Analogs

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Popular Name: (2S)-2-(5-nitro-2-oxo-1-pyridyl)-N-phenyl-propanamide (2S)-2-(5-nitro-2-oxo-1-pyridyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.73	7.86	-18.7	1	7	0	97	287.275	4	↓ MOL2 SDF SMILES Flexibase

71515068

Analogs

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Popular Name: (2R)-2-(5-nitro-2-oxo-1-pyridyl)-N-phenyl-propanamide (2R)-2-(5-nitro-2-oxo-1-pyridyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.73	7.85	-18.51	1	7	0	97	287.275	4	↓ MOL2 SDF SMILES Flexibase

71515325

Analogs

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Popular Name: 2-(5-methyl-2-oxo-1-pyridyl)-N-(4-nitrophenyl)acetamide 2-(5-methyl-2-oxo-1-pyridyl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.81	7.17	-21.51	1	7	0	97	287.275	4	↓ MOL2 SDF SMILES Flexibase

71515395

Analogs

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Popular Name: 2-(5-methyl-2-oxo-1-pyridyl)-N-(3-nitrophenyl)acetamide 2-(5-methyl-2-oxo-1-pyridyl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.79	7.16	-25.05	1	7	0	97	287.275	4	↓ MOL2 SDF SMILES Flexibase

71516087

Analogs

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Popular Name: 4-[[2-(5-fluoro-2-oxo-1-pyridyl)acetyl]amino]benzoic 4-[[2-(5-fluoro-2-oxo-1-pyridyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.48	6.43	-62.29	1	6	-1	91	289.242	4	↓ MOL2 SDF SMILES Flexibase

71516115

Analogs

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Popular Name: 2-(5-fluoro-2-oxo-1-pyridyl)-N-(4-nitrophenyl)acetamide 2-(5-fluoro-2-oxo-1-pyridyl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.52	6.58	-19.89	1	7	0	97	291.238	4	↓ MOL2 SDF SMILES Flexibase

71516186

Analogs

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Popular Name: 2-(5-fluoro-2-oxo-1-pyridyl)-N-(3-nitrophenyl)acetamide 2-(5-fluoro-2-oxo-1-pyridyl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.50	6.57	-18	1	7	0	97	291.238	4	↓ MOL2 SDF SMILES Flexibase

71516701

Analogs

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Popular Name: N-(2,6-diisopropylphenyl)-2-(3-methyl-2-oxo-1-pyridyl)acetamide N-(2,6-diisopropylphenyl)-2-(3-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.58	10.44	-17.17	1	4	0	51	326.44	5	↓ MOL2 SDF SMILES Flexibase

71516705

Analogs

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Popular Name: 2-(3-methyl-2-oxo-1-pyridyl)-N-(4-nitrophenyl)acetamide 2-(3-methyl-2-oxo-1-pyridyl)-N-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.49	7.2	-22.46	1	7	0	97	287.275	4	↓ MOL2 SDF SMILES Flexibase

71526386

Analogs

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Popular Name: 2-(2-methyl-3-nitro-6-oxo-1-pyridyl)-N-phenyl-acetamide 2-(2-methyl-3-nitro-6-oxo-1-pyri…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.58	6.68	-17.13	1	7	0	97	287.275	4	↓ MOL2 SDF SMILES Flexibase

19988565

Analogs

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Popular Name: 1-{2-[(2-bromophenyl)amino]-2-oxoethyl}-6-oxo-1,6-dihydropyridine-3-carboxylic acid 1-{2-[(2-bromophenyl)amino]-2-ox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.74	6.17	-53.33	1	6	-1	91	350.148	4	↓ MOL2 SDF SMILES Flexibase

19999790

Analogs

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Popular Name: N-(2-amino-5-chloro-phenyl)-2-(5-bromo-2-oxo-1-pyridyl)acetamide N-(2-amino-5-chloro-phenyl)-2-(5…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.30	5.1	-21.15	3	5	0	77	356.607	3	↓ MOL2 SDF SMILES Flexibase

20005973

Analogs

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Popular Name: (2S)-N-(4-carbamothioylphenyl)-2-(2-oxo-1-pyridyl)propanamide (2S)-N-(4-carbamothioylphenyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.29	6.42	-31.09	3	5	0	77	301.371	4	↓ MOL2 SDF SMILES Flexibase

20005976

Analogs

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Popular Name: (2R)-N-(4-carbamothioylphenyl)-2-(2-oxo-1-pyridyl)propanamide (2R)-N-(4-carbamothioylphenyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.29	5.26	-28.36	3	5	0	77	301.371	4	↓ MOL2 SDF SMILES Flexibase

11984588

Analogs

5918126

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Popular Name: N-[2-(difluoromethylsulfanyl)phenyl]-2-[5-(dimethylsulfamoyl)-2-oxo-1-pyridyl]-acetamide N-[2-(difluoromethylsulfanyl)phe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.66	-2.62	-21.85	1	7	0	88	417.459	7	↓ MOL2 SDF SMILES Flexibase

36332782

Analogs

4494225

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Popular Name: 2-[5-(diethylsulfamoyl)-2-oxo-1-pyridyl]-N-(4-pentylphenyl)acetamide 2-[5-(diethylsulfamoyl)-2-oxo-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.84	9.34	-18.92	1	7	0	88	433.574	11	↓ MOL2 SDF SMILES Flexibase

36333606

Analogs

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Popular Name: N-butyl-2-[5-(diethylsulfamoyl)-2-oxo-1-pyridyl]-N-phenyl-acetamide N-butyl-2-[5-(diethylsulfamoyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.15	9.64	-16.33	0	7	0	80	419.547	10	↓ MOL2 SDF SMILES Flexibase

36333650

Analogs

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Popular Name: 2-[5-(diethylsulfamoyl)-2-oxo-1-pyridyl]-N-(3,4-dipropoxyphenyl)acetamide 2-[5-(diethylsulfamoyl)-2-oxo-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.87	8.2	-21.1	1	9	0	107	479.599	13	↓ MOL2 SDF SMILES Flexibase

22654700

Analogs

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Popular Name: N-(4-methyl-3-sulfamoyl-phenyl)-2-[2-oxo-5-(trifluoromethyl)-1-pyridyl]acetamide N-(4-methyl-3-sulfamoyl-phenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.37	2.48	-21.23	3	7	0	111	389.355	5	↓ MOL2 SDF SMILES Flexibase

13008143

Analogs

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Popular Name: 2-(5-bromo-2-oxo-1-pyridyl)-N-isopropyl-N-phenyl-acetamide 2-(5-bromo-2-oxo-1-pyridyl)-N-is…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.13	9.29	-15.35	0	4	0	42	349.228	4	↓ MOL2 SDF SMILES Flexibase

13011783

Analogs

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Popular Name: 2-[2-oxo-3-(trifluoromethyl)-1-pyridyl]-N-[3-(trifluoromethoxy)phenyl]acetamide 2-[2-oxo-3-(trifluoromethyl)-1-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.92	6.6	-22.25	1	5	0	60	380.244	6	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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