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Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2R)-1-[(2-bromophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(2-bromophenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.55 7.92 -35.7 2 2 1 20 324.286 5 ↓
Mid Mid (pH 6-8) 3.55 10.17 -104.58 3 2 2 21 325.294 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2S)-1-[(2-bromophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(2-bromophenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.55 8.26 -37.79 2 2 1 20 324.286 5 ↓
Mid Mid (pH 6-8) 3.55 10.16 -112.64 3 2 2 21 325.294 5 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(5-bromo-2-fluoro-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(5-bromo-2-fluoro-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.69 8.77 -32.16 2 2 1 20 342.276 5 ↓
Mid Mid (pH 6-8) 3.69 10.65 -108.92 3 2 2 21 343.284 5 ↓

Analogs

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Popular Name: N-[[(2S)-1-[(5-bromo-2-fluoro-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(5-bromo-2-fluoro-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.69 8.45 -37.48 2 2 1 20 342.276 5 ↓
Mid Mid (pH 6-8) 3.69 10.47 -115.06 3 2 2 21 343.284 5 ↓

Analogs

44722898
44722898

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Popular Name: N-[[(2R)-1-[(2-bromo-4-fluoro-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(2-bromo-4-fluoro-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.69 8.24 -41.8 2 2 1 20 342.276 5 ↓
Mid Mid (pH 6-8) 3.69 10.27 -120.8 3 2 2 21 343.284 5 ↓

Analogs

44722898
44722898

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Popular Name: N-[[(2S)-1-[(2-bromo-4-fluoro-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(2-bromo-4-fluoro-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.69 8.14 -39.19 2 2 1 20 342.276 5 ↓
Mid Mid (pH 6-8) 3.69 10.28 -112 3 2 2 21 343.284 5 ↓

Analogs

43910861
43910861
43910865
43910865
43910869
43910869
43910873
43910873

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2R)-1-[(2-fluorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(2-fluorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.90 8.16 -30.08 2 2 1 20 263.38 5 ↓
Mid Mid (pH 6-8) 2.90 10.03 -104.24 3 2 2 21 264.388 5 ↓

Analogs

43910861
43910861
43910865
43910865
43910869
43910869
43910873
43910873

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2S)-1-[(2-fluorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(2-fluorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.90 7.84 -39.08 2 2 1 20 263.38 5 ↓
Mid Mid (pH 6-8) 2.90 9.85 -113.91 3 2 2 21 264.388 5 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(4-chlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(4-chlorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.46 10.44 -121.52 3 2 2 21 280.843 5 ↓
Mid Mid (pH 6-8) 3.46 8.65 -38.77 2 2 1 20 279.835 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2S)-1-[(4-chlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(4-chlorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.46 10.48 -121.43 3 2 2 21 280.843 5 ↓
Mid Mid (pH 6-8) 3.46 8.51 -38.94 2 2 1 20 279.835 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2R)-1-[(3-chlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(3-chlorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.44 8.64 -39.45 2 2 1 20 279.835 5 ↓
Mid Mid (pH 6-8) 3.44 10.44 -120.38 3 2 2 21 280.843 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2S)-1-[(3-chlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(3-chlorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.44 8.5 -35.8 2 2 1 20 279.835 5 ↓
Mid Mid (pH 6-8) 3.44 10.47 -117.06 3 2 2 21 280.843 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2R)-1-[(2,4-dichlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(2,4-dichlorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.07 8.62 -40.85 2 2 1 20 314.28 5 ↓
Mid Mid (pH 6-8) 4.07 10.65 -120.02 3 2 2 21 315.288 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2S)-1-[(2,4-dichlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(2,4-dichlorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.07 8.41 -38.48 2 2 1 20 314.28 5 ↓
Mid Mid (pH 6-8) 4.07 10.61 -111.98 3 2 2 21 315.288 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2R)-1-[(3-bromophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(3-bromophenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.57 8.74 -39.56 2 2 1 20 324.286 5 ↓
Mid Mid (pH 6-8) 3.57 10.55 -120.78 3 2 2 21 325.294 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2S)-1-[(3-bromophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(3-bromophenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.57 8.61 -35.72 2 2 1 20 324.286 5 ↓
Mid Mid (pH 6-8) 3.57 10.58 -116.92 3 2 2 21 325.294 5 ↓

Analogs

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Popular Name: (1-Benzyl-piperidin-2-ylmethyl)-cyclopropyl-amine (1-Benzyl-piperidin-2-ylmethyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.79 9.92 -114.44 3 2 2 21 246.398 5 ↓
Mid Mid (pH 6-8) 2.79 8.13 -35.96 2 2 1 20 245.39 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (1-Benzyl-piperidin-2-ylmethyl)-cyclopropyl-amine (1-Benzyl-piperidin-2-ylmethyl)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.79 9.96 -114.33 3 2 2 21 246.398 5 ↓
Mid Mid (pH 6-8) 2.79 7.99 -36.05 2 2 1 20 245.39 5 ↓

Analogs

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Popular Name: N-[[(2R)-1-(p-tolylmethyl)-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-(p-tolylmethyl)-2-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.23 10.6 -114.72 3 2 2 21 260.425 5 ↓
Mid Mid (pH 6-8) 3.23 8.81 -35.99 2 2 1 20 259.417 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2S)-1-(p-tolylmethyl)-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-(p-tolylmethyl)-2-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.23 10.64 -114.62 3 2 2 21 260.425 5 ↓
Mid Mid (pH 6-8) 3.23 8.67 -36.11 2 2 1 20 259.417 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2R)-1-[(4-fluorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(4-fluorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.95 9.99 -122.75 3 2 2 21 264.388 5 ↓
Mid Mid (pH 6-8) 2.95 8.2 -39.93 2 2 1 20 263.38 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2S)-1-[(4-fluorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(4-fluorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.95 10.03 -122.62 3 2 2 21 264.388 5 ↓
Mid Mid (pH 6-8) 2.95 8.06 -40 2 2 1 20 263.38 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2R)-1-(m-tolylmethyl)-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-(m-tolylmethyl)-2-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.21 10.6 -115.02 3 2 2 21 260.425 5 ↓
Mid Mid (pH 6-8) 3.21 8.79 -35.9 2 2 1 20 259.417 5 ↓

Analogs

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Popular Name: N-[[(2S)-1-(m-tolylmethyl)-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-(m-tolylmethyl)-2-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.21 10.63 -115.09 3 2 2 21 260.425 5 ↓
Mid Mid (pH 6-8) 3.21 8.66 -36.29 2 2 1 20 259.417 5 ↓

Analogs

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Popular Name: N-[[(2R)-1-(o-tolylmethyl)-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-(o-tolylmethyl)-2-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.19 10.24 -113.62 3 2 2 21 260.425 5 ↓
Mid Mid (pH 6-8) 3.19 8.36 -39.51 2 2 1 20 259.417 5 ↓

Analogs

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Popular Name: N-[[(2S)-1-(o-tolylmethyl)-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-(o-tolylmethyl)-2-pip…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.19 10.21 -114.41 3 2 2 21 260.425 5 ↓
Mid Mid (pH 6-8) 3.19 8.03 -39.62 2 2 1 20 259.417 5 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(4-bromophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(4-bromophenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.60 10.55 -121.89 3 2 2 21 325.294 5 ↓
Mid Mid (pH 6-8) 3.60 8.75 -38.84 2 2 1 20 324.286 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2S)-1-[(4-bromophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(4-bromophenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.60 10.59 -121.83 3 2 2 21 325.294 5 ↓
Mid Mid (pH 6-8) 3.60 8.62 -38.92 2 2 1 20 324.286 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2R)-1-[(2-chloro-4-fluoro-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(2-chloro-4-fluoro-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 8.18 -41.87 2 2 1 20 297.825 5 ↓
Mid Mid (pH 6-8) 3.56 10.21 -121.07 3 2 2 21 298.833 5 ↓

Analogs

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Popular Name: N-[[(2S)-1-[(2-chloro-4-fluoro-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(2-chloro-4-fluoro-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.56 7.98 -39.3 2 2 1 20 297.825 5 ↓
Mid Mid (pH 6-8) 3.56 10.17 -112.94 3 2 2 21 298.833 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2R)-1-[(2-chlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(2-chlorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.42 7.84 -35.86 2 2 1 20 279.835 5 ↓
Mid Mid (pH 6-8) 3.42 10.07 -105.4 3 2 2 21 280.843 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[(2S)-1-[(2-chlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(2-chlorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.42 8.22 -37.9 2 2 1 20 279.835 5 ↓
Mid Mid (pH 6-8) 3.42 10.11 -112.82 3 2 2 21 280.843 5 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(3-methoxyphenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(3-methoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.82 9.22 -116.87 3 3 2 30 276.424 6 ↓
Mid Mid (pH 6-8) 2.82 7.43 -38.78 2 3 1 29 275.416 6 ↓

Analogs

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Popular Name: N-[[(2S)-1-[(3-methoxyphenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(3-methoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.82 9.26 -114.1 3 3 2 30 276.424 6 ↓
Mid Mid (pH 6-8) 2.82 7.29 -35.27 2 3 1 29 275.416 6 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(4-isopropylphenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(4-isopropylphenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.30 11.85 -115.23 3 2 2 21 288.479 6 ↓
Mid Mid (pH 6-8) 4.30 10.06 -35.85 2 2 1 20 287.471 6 ↓

Analogs

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Popular Name: N-[[(2S)-1-[(4-isopropylphenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(4-isopropylphenyl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.30 11.89 -114.97 3 2 2 21 288.479 6 ↓
Mid Mid (pH 6-8) 4.30 9.92 -35.79 2 2 1 20 287.471 6 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(3,4-dichlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(3,4-dichlorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.07 9.1 -42.43 2 2 1 20 314.28 5 ↓
Mid Mid (pH 6-8) 4.07 10.9 -127.18 3 2 2 21 315.288 5 ↓

Analogs

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Popular Name: N-[[(2S)-1-[(3,4-dichlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(3,4-dichlorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.07 8.96 -38.93 2 2 1 20 314.28 5 ↓
Mid Mid (pH 6-8) 4.07 10.93 -123.92 3 2 2 21 315.288 5 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(2,6-dichlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(2,6-dichlorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.05 8.15 -35.48 2 2 1 20 314.28 5 ↓
Mid Mid (pH 6-8) 4.05 10.19 -100.61 3 2 2 21 315.288 5 ↓

Analogs

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Popular Name: N-[[(2S)-1-[(2,6-dichlorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(2,6-dichlorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.05 7.99 -35.57 2 2 1 20 314.28 5 ↓
Mid Mid (pH 6-8) 4.05 10.17 -100.78 3 2 2 21 315.288 5 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(3-fluoro-4-methoxy-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(3-fluoro-4-methoxy-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.94 9.3 -126.84 3 3 2 30 294.414 6 ↓
Mid Mid (pH 6-8) 2.94 7.5 -44.87 2 3 1 29 293.406 6 ↓

Analogs

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Popular Name: N-[[(2S)-1-[(3-fluoro-4-methoxy-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(3-fluoro-4-methoxy-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.94 9.34 -122.73 3 3 2 30 294.414 6 ↓
Mid Mid (pH 6-8) 2.94 7.37 -39.68 2 3 1 29 293.406 6 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(4-bromo-2-fluoro-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(4-bromo-2-fluoro-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.69 8.52 -41.79 2 2 1 20 342.276 5 ↓
Mid Mid (pH 6-8) 3.69 10.5 -121.55 3 2 2 21 343.284 5 ↓

Analogs

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Popular Name: N-[[(2S)-1-[(4-bromo-2-fluoro-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(4-bromo-2-fluoro-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.69 8.07 -38.92 2 2 1 20 342.276 5 ↓
Mid Mid (pH 6-8) 3.69 10.29 -114.51 3 2 2 21 343.284 5 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(5-chloro-2-methoxy-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(5-chloro-2-methoxy-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 7.27 -38.23 2 3 1 29 309.861 6 ↓
Mid Mid (pH 6-8) 3.45 9.48 -109.98 3 3 2 30 310.869 6 ↓

Analogs

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Popular Name: N-[[(2S)-1-[(5-chloro-2-methoxy-phenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(5-chloro-2-methoxy-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 8.09 -36 2 3 1 29 309.861 6 ↓
Mid Mid (pH 6-8) 3.45 10.02 -112.49 3 3 2 30 310.869 6 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(2,3-difluorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(2,3-difluorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 7.98 -44.92 2 2 1 20 281.37 5 ↓
Mid Mid (pH 6-8) 3.02 9.95 -122.95 3 2 2 21 282.378 5 ↓

Analogs

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Popular Name: N-[[(2S)-1-[(2,3-difluorophenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(2,3-difluorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.02 7.51 -40.03 2 2 1 20 281.37 5 ↓
Mid Mid (pH 6-8) 3.02 9.73 -113.96 3 2 2 21 282.378 5 ↓

Analogs

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Popular Name: N-[[(2R)-1-[(3,5-dimethylphenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2R)-1-[(3,5-dimethylphenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 11.25 -115.59 3 2 2 21 274.452 5 ↓
Mid Mid (pH 6-8) 3.61 9.45 -36.05 2 2 1 20 273.444 5 ↓

Analogs

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Popular Name: N-[[(2S)-1-[(3,5-dimethylphenyl)methyl]-2-piperidyl]methyl]cyclopropanamine N-[[(2S)-1-[(3,5-dimethylphenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.61 11.29 -115.61 3 2 2 21 274.452 5 ↓
Mid Mid (pH 6-8) 3.61 9.31 -36.21 2 2 1 20 273.444 5 ↓

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
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Structural Results Found: (before additional filtering)

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