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Analogs

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Popular Name: (8-bromo-5-fluoro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (8-bromo-5-fluoro-2,3-dihydro-1H…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.17 5.34 -6.8 3 3 0 51 296.143 1 ↓
Mid Mid (pH 6-8) 3.17 5.73 -22.74 4 3 1 52 297.151 1 ↓

Analogs

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Popular Name: (7-iodo-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-iodo-2,3-dihydro-1H-cyclopent…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.35 5.92 -25.47 4 3 1 52 326.161 1 ↓

Analogs

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Popular Name: (5-iodo-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5-iodo-2,3-dihydro-1H-cyclopent…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 6.02 -22.51 4 3 1 52 326.161 1 ↓

Analogs

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Popular Name: 9-hydrazino-N,N-dimethyl-2,3-dihydro-1H-cyclopenta[b]quinolin-7-amine 9-hydrazino-N,N-dimethyl-2,3-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.37 5.25 -22.89 4 4 1 55 243.334 2 ↓

Analogs

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Popular Name: (6-chloro-5-fluoro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (6-chloro-5-fluoro-2,3-dihydro-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 5.43 -25.03 4 3 1 52 252.7 1 ↓
Mid Mid (pH 6-8) 3.04 5.04 -10.08 3 3 0 51 251.692 1 ↓

Analogs

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Popular Name: (6,7-diethoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (6,7-diethoxy-2,3-dihydro-1H-cyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.67 5.92 -27.02 4 5 1 71 288.371 5 ↓

Analogs

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Popular Name: 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylhydrazine 2,3-dihydro-1H-cyclopenta[b]quin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.29 4.84 -23.11 4 3 1 52 200.265 1 ↓

Analogs

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Popular Name: (5-methoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5-methoxy-2,3-dihydro-1H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 4.25 -21.77 4 4 1 61 230.291 2 ↓

Analogs

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Popular Name: [5-(trifluoromethoxy)-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl]hydrazine [5-(trifluoromethoxy)-2,3-dihydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.21 4.74 -23.64 4 4 1 61 284.261 3 ↓
Hi High (pH 8-9.5) 3.21 4.31 -9.07 3 4 0 60 283.253 3 ↓

Analogs

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Popular Name: (6,8-difluoro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (6,8-difluoro-2,3-dihydro-1H-cyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.52 5.04 -25.15 4 3 1 52 236.245 1 ↓
Hi High (pH 8-9.5) 2.52 4.65 -4.94 3 3 0 51 235.237 1 ↓

Analogs

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Popular Name: [7-(2,2,2-trifluoroethoxy)-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl]hydrazine [7-(2,2,2-trifluoroethoxy)-2,3-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.25 5.52 -29.19 4 4 1 61 298.288 4 ↓

Analogs

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Popular Name: [5-(2,2,2-trifluoroethoxy)-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl]hydrazine [5-(2,2,2-trifluoroethoxy)-2,3-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.23 5.66 -25.33 4 4 1 61 298.288 4 ↓

Analogs

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Popular Name: (7-propyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-propyl-2,3-dihydro-1H-cyclope…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.57 7.03 -23.12 4 3 1 52 242.346 3 ↓

Analogs

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Popular Name: (5,8-diethoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5,8-diethoxy-2,3-dihydro-1H-cyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.06 5.83 -20.22 4 5 1 71 288.371 5 ↓

Analogs

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Popular Name: (7-bromo-5-methyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-bromo-5-methyl-2,3-dihydro-1H…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 6.21 -24.32 4 3 1 52 293.188 1 ↓

Analogs

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Popular Name: (5-propoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5-propoxy-2,3-dihydro-1H-cyclop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 6 -21.35 4 4 1 61 258.345 4 ↓

Analogs

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Popular Name: (7-ethoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-ethoxy-2,3-dihydro-1H-cyclope…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 5.07 -24.6 4 4 1 61 244.318 3 ↓

Analogs

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Popular Name: (5,7-dichloro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5,7-dichloro-2,3-dihydro-1H-cyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.55 5.94 -23.01 4 3 1 52 269.155 1 ↓
Mid Mid (pH 6-8) 3.55 5.58 -6.47 3 3 0 51 268.147 1 ↓

Analogs

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Popular Name: (6,8-dichloro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (6,8-dichloro-2,3-dihydro-1H-cyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.55 5.97 -24.49 4 3 1 52 269.155 1 ↓
Hi High (pH 8-9.5) 3.73 5.98 -22.67 4 3 1 56 269.155 0 ↓
Hi High (pH 8-9.5) 3.55 5.59 -4.68 3 3 0 51 268.147 1 ↓

Analogs

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Popular Name: (5-chloro-7-methyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5-chloro-7-methyl-2,3-dihydro-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.32 6.09 -21.91 4 3 1 52 248.737 1 ↓
Hi High (pH 8-9.5) 3.32 5.73 -8.34 3 3 0 51 247.729 1 ↓

Analogs

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Popular Name: (5,8-dichloro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5,8-dichloro-2,3-dihydro-1H-cyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.55 6.04 -21.46 4 3 1 52 269.155 1 ↓
Mid Mid (pH 6-8) 3.55 5.68 -6.57 3 3 0 51 268.147 1 ↓

Analogs

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Popular Name: (5,7-dimethyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5,7-dimethyl-2,3-dihydro-1H-cyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 6.27 -21.83 4 3 1 52 228.319 1 ↓

Analogs

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Popular Name: (7-methyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-methyl-2,3-dihydro-1H-cyclope…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.72 5.5 -22.76 4 3 1 52 214.292 1 ↓

Analogs

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Popular Name: (8-chloro-5-fluoro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (8-chloro-5-fluoro-2,3-dihydro-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 5.56 -22.3 4 3 1 52 252.7 1 ↓
Mid Mid (pH 6-8) 3.04 5.16 -7.69 3 3 0 51 251.692 1 ↓

Analogs

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Popular Name: (7-ethyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-ethyl-2,3-dihydro-1H-cyclopen…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.18 6.27 -22.78 4 3 1 52 228.319 2 ↓

Analogs

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Popular Name: (5-ethoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5-ethoxy-2,3-dihydro-1H-cyclope…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.68 5.2 -21.41 4 4 1 61 244.318 3 ↓

Analogs

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Popular Name: (5-fluoro-8-methyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5-fluoro-8-methyl-2,3-dihydro-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.81 5.8 -22.9 4 3 1 52 232.282 1 ↓
Hi High (pH 8-9.5) 2.81 5.4 -9.45 3 3 0 51 231.274 1 ↓

Analogs

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Popular Name: (8-chloro-5-methyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (8-chloro-5-methyl-2,3-dihydro-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.32 6.23 -22.96 4 3 1 52 248.737 1 ↓
Hi High (pH 8-9.5) 3.50 6.25 -21.33 4 3 1 56 248.737 0 ↓

Analogs

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Popular Name: (5-ethyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5-ethyl-2,3-dihydro-1H-cyclopen…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.16 6.37 -21.88 4 3 1 52 228.319 2 ↓

Analogs

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Popular Name: (8-chloro-5,7-dimethoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (8-chloro-5,7-dimethoxy-2,3-dihy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.92 4.25 -22.96 4 5 1 71 294.762 3 ↓
Hi High (pH 8-9.5) 2.92 3.81 -9.66 3 5 0 69 293.754 3 ↓

Analogs

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Popular Name: (7-bromo-5-chloro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-bromo-5-chloro-2,3-dihydro-1H…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.68 6.03 -23.07 4 3 1 52 313.606 1 ↓
Mid Mid (pH 6-8) 3.68 5.68 -6.48 3 3 0 51 312.598 1 ↓

Analogs

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Popular Name: (7-fluoro-5-methyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-fluoro-5-methyl-2,3-dihydro-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.84 5.67 -24.73 4 3 1 52 232.282 1 ↓

Analogs

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Popular Name: (6-chloro-5-methyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (6-chloro-5-methyl-2,3-dihydro-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.32 6.05 -24.19 4 3 1 52 248.737 1 ↓

Analogs

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Popular Name: (5-methoxy-8-methyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5-methoxy-8-methyl-2,3-dihydro-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.70 5.13 -21.92 4 4 1 61 244.318 2 ↓

Analogs

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Popular Name: (5-bromo-7-methyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5-bromo-7-methyl-2,3-dihydro-1H…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 6.2 -21.88 4 3 1 52 293.188 1 ↓
Hi High (pH 8-9.5) 3.45 5.86 -8.19 3 3 0 51 292.18 1 ↓

Analogs

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Popular Name: (7-chloro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-chloro-2,3-dihydro-1H-cyclope…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.95 5.35 -25.41 4 3 1 52 234.71 1 ↓
Hi High (pH 8-9.5) 3.12 5.37 -24.89 4 3 1 56 234.71 0 ↓

Analogs

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Popular Name: (8-chloro-5-methoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (8-chloro-5-methoxy-2,3-dihydro-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.93 4.88 -21.49 4 4 1 61 264.736 2 ↓
Hi High (pH 8-9.5) 2.93 4.45 -8.71 3 4 0 60 263.728 2 ↓

Analogs

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Popular Name: (5-fluoro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5-fluoro-2,3-dihydro-1H-cyclope…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.41 4.95 -23.13 4 3 1 52 218.255 1 ↓
Hi High (pH 8-9.5) 2.41 4.56 -10.51 3 3 0 51 217.247 1 ↓

Analogs

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Popular Name: (7-isopropyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-isopropyl-2,3-dihydro-1H-cycl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.78 6.75 -22.81 4 3 1 52 242.346 2 ↓

Analogs

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Popular Name: [7-(trifluoromethoxy)-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl]hydrazine [7-(trifluoromethoxy)-2,3-dihydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.24 4.64 -26.1 4 4 1 61 284.261 3 ↓
Hi High (pH 8-9.5) 3.41 4.63 -26.09 4 4 1 65 284.261 2 ↓

Analogs

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Popular Name: (5,8-difluoro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5,8-difluoro-2,3-dihydro-1H-cyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.52 5.06 -22.53 4 3 1 52 236.245 1 ↓
Mid Mid (pH 6-8) 2.52 4.68 -7.84 3 3 0 51 235.237 1 ↓

Analogs

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Popular Name: (7-bromo-5-fluoro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-bromo-5-fluoro-2,3-dihydro-1H…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.17 5.55 -23.74 4 3 1 52 297.151 1 ↓
Mid Mid (pH 6-8) 3.17 5.16 -7.79 3 3 0 51 296.143 1 ↓

Analogs

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Popular Name: (5-chloro-7-fluoro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5-chloro-7-fluoro-2,3-dihydro-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.06 5.49 -23.3 4 3 1 52 252.7 1 ↓
Mid Mid (pH 6-8) 2.06 5.13 -6.51 3 3 0 51 251.692 1 ↓

Analogs

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Popular Name: (5,6-dichloro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (5,6-dichloro-2,3-dihydro-1H-cyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.55 5.88 -24.29 4 3 1 52 269.155 1 ↓
Mid Mid (pH 6-8) 3.55 5.52 -8.44 3 3 0 51 268.147 1 ↓

Analogs

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Popular Name: (6,8-dimethoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (6,8-dimethoxy-2,3-dihydro-1H-cy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.31 3.91 -22.63 4 5 1 71 260.317 3 ↓

Analogs

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Popular Name: (6,7-difluoro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (6,7-difluoro-2,3-dihydro-1H-cyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.55 4.96 -28.33 4 3 1 52 236.245 1 ↓
Hi High (pH 8-9.5) 1.55 4.59 -6.5 3 3 0 51 235.237 1 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (6,7-dimethoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (6,7-dimethoxy-2,3-dihydro-1H-cy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.91 4.08 -27.01 4 5 1 71 260.317 3 ↓

Analogs

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Popular Name: (6,8-dimethyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (6,8-dimethyl-2,3-dihydro-1H-cyc…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 6.37 -23.17 4 3 1 52 228.319 1 ↓

Analogs

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Popular Name: (7-chloro-5-fluoro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (7-chloro-5-fluoro-2,3-dihydro-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 5.45 -23.62 4 3 1 52 252.7 1 ↓
Mid Mid (pH 6-8) 3.04 5.06 -7.72 3 3 0 51 251.692 1 ↓

Analogs

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Popular Name: (8-fluoro-5-methyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)hydrazine (8-fluoro-5-methyl-2,3-dihydro-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.81 5.73 -23.29 4 3 1 52 232.282 1 ↓
Hi High (pH 8-9.5) 2.98 5.74 -21.72 4 3 1 56 232.282 0 ↓

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 10908 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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