ZINC 12

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ZINC Item

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50653346

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(cyclopentylmethyl)-6-(methylamino)pyridine-3-sulfonamide N-(cyclopentylmethyl)-6-(methyla…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.92	2.03	-9.74	2	5	0	71	269.37	5	↓ MOL2 SDF SMILES Flexibase

50653350

Analogs

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Popular Name: N-(cyclopentylmethyl)-6-(ethylamino)pyridine-3-sulfonamide N-(cyclopentylmethyl)-6-(ethylam…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.29	2.83	-9.28	2	5	0	71	283.397	6	↓ MOL2 SDF SMILES Flexibase

50653353

Analogs

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Popular Name: N-(cyclopentylmethyl)-6-(propylamino)pyridine-3-sulfonamide N-(cyclopentylmethyl)-6-(propyla…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.80	3.6	-9	2	5	0	71	297.424	7	↓ MOL2 SDF SMILES Flexibase

50653375

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(cyclopentylmethyl)-2-(methylamino)pyridine-3-sulfonamide N-(cyclopentylmethyl)-2-(methyla…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.70	2.78	-9.76	2	5	0	71	269.37	5	↓ MOL2 SDF SMILES Flexibase

50653379

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(cyclopentylmethyl)-2-(ethylamino)pyridine-3-sulfonamide N-(cyclopentylmethyl)-2-(ethylam…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.08	3.61	-9.47	2	5	0	71	283.397	6	↓ MOL2 SDF SMILES Flexibase

50653382

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(cyclopentylmethyl)-2-(propylamino)pyridine-3-sulfonamide N-(cyclopentylmethyl)-2-(propyla…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.58	4.37	-9.28	2	5	0	71	297.424	7	↓ MOL2 SDF SMILES Flexibase

50653403

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-N-(cyclopentylmethyl)-2-(methylamino)pyridine-3-sulfonamide 5-bromo-N-(cyclopentylmethyl)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.65	3.37	-8.17	2	5	0	71	348.266	5	↓ MOL2 SDF SMILES Flexibase

50653405

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-N-(cyclopentylmethyl)-2-(ethylamino)pyridine-3-sulfonamide 5-bromo-N-(cyclopentylmethyl)-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.03	4.2	-7.81	2	5	0	71	362.293	6	↓ MOL2 SDF SMILES Flexibase

50653408

Analogs

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Popular Name: 6-amino-N-(cyclopentylmethyl)pyridine-3-sulfonamide 6-amino-N-(cyclopentylmethyl)pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.54	1.12	-9.86	3	5	0	85	255.343	4	↓ MOL2 SDF SMILES Flexibase

50653418

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-amino-N-(cyclopentylmethyl)pyridine-3-sulfonamide 2-amino-N-(cyclopentylmethyl)pyr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.32	1.53	-9.41	3	5	0	85	255.343	4	↓ MOL2 SDF SMILES Flexibase

50653430

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-amino-5-bromo-N-(cyclopentylmethyl)pyridine-3-sulfonamide 2-amino-5-bromo-N-(cyclopentylme…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.28	2.15	-8.13	3	5	0	85	334.239	4	↓ MOL2 SDF SMILES Flexibase

40663446

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dichloro-N-[(1-hydroxycyclopentyl)methyl]pyridine-3-sulfonamide 5,6-dichloro-N-[(1-hydroxycyclop…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.40	0.22	-9.12	2	5	0	79	325.217	4	↓ MOL2 SDF SMILES Flexibase

40663447

Analogs

37979735
37979736

Draw Identity 99% 90% 80% 70%

Popular Name: 6-chloro-N-[(1-hydroxycyclopentyl)methyl]pyridine-3-sulfonamide 6-chloro-N-[(1-hydroxycyclopenty…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.79	-0.21	-10.18	2	5	0	79	290.772	4	↓ MOL2 SDF SMILES Flexibase

70305320

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-amino-N-[(1S)-1-cyclopentylethyl]pyridine-3-sulfonamide 6-amino-N-[(1S)-1-cyclopentyleth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.87	1.73	-9.7	3	5	0	85	269.37	4	↓ MOL2 SDF SMILES Flexibase

70305321

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-amino-N-[(1R)-1-cyclopentylethyl]pyridine-3-sulfonamide 6-amino-N-[(1R)-1-cyclopentyleth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.87	1.53	-9.87	3	5	0	85	269.37	4	↓ MOL2 SDF SMILES Flexibase

70307439

Analogs

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Popular Name: 2-chloro-N-[(1S)-1-cyclopentylethyl]pyridine-3-sulfonamide 2-chloro-N-[(1S)-1-cyclopentylet…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.85	3.48	-9.78	1	4	0	59	288.8	4	↓ MOL2 SDF SMILES Flexibase

70307440

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 2-chloro-N-[(1R)-1-cyclopentylethyl]pyridine-3-sulfonamide 2-chloro-N-[(1R)-1-cyclopentylet…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.85	3.4	-9.61	1	4	0	59	288.8	4	↓ MOL2 SDF SMILES Flexibase

70307445

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-chloro-N-[(1S)-1-cyclopentylethyl]pyridine-3-sulfonamide 6-chloro-N-[(1S)-1-cyclopentylet…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.07	3.42	-8.56	1	4	0	59	288.8	4	↓ MOL2 SDF SMILES Flexibase

70307446

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-chloro-N-[(1R)-1-cyclopentylethyl]pyridine-3-sulfonamide 6-chloro-N-[(1R)-1-cyclopentylet…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.07	3.22	-8.67	1	4	0	59	288.8	4	↓ MOL2 SDF SMILES Flexibase

70307455

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-2-chloro-N-[(1S)-1-cyclopentylethyl]pyridine-3-sulfonamide 5-bromo-2-chloro-N-[(1S)-1-cyclo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.80	4.08	-6.77	1	4	0	59	367.696	4	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.80	3.93	-36.94	0	4	-1	61	366.688	4	↓ MOL2 SDF SMILES Flexibase

70307456

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-2-chloro-N-[(1R)-1-cyclopentylethyl]pyridine-3-sulfonamide 5-bromo-2-chloro-N-[(1R)-1-cyclo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.80	4	-6.6	1	4	0	59	367.696	4	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.80	4.14	-35.44	0	4	-1	61	366.688	4	↓ MOL2 SDF SMILES Flexibase

70308443

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-N-[(1S)-1-cyclopentylethyl]-2-hydrazino-pyridine-3-sulfonamide 5-bromo-N-[(1S)-1-cyclopentyleth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.37	2.21	-8.69	4	6	0	97	363.281	5	↓ MOL2 SDF SMILES Flexibase

70308444

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-N-[(1R)-1-cyclopentylethyl]-2-hydrazino-pyridine-3-sulfonamide 5-bromo-N-[(1R)-1-cyclopentyleth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.37	2.61	-9.16	4	6	0	97	363.281	5	↓ MOL2 SDF SMILES Flexibase

70308445

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S)-1-cyclopentylethyl]-6-hydrazino-pyridine-3-sulfonamide N-[(1S)-1-cyclopentylethyl]-6-hy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.63	1.63	-10.67	4	6	0	97	284.385	5	↓ MOL2 SDF SMILES Flexibase

70308446

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-1-cyclopentylethyl]-6-hydrazino-pyridine-3-sulfonamide N-[(1R)-1-cyclopentylethyl]-6-hy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.63	1.43	-10.76	4	6	0	97	284.385	5	↓ MOL2 SDF SMILES Flexibase

70308451

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S)-1-cyclopentylethyl]-2-hydrazino-pyridine-3-sulfonamide N-[(1S)-1-cyclopentylethyl]-2-hy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.41	1.62	-10.11	4	6	0	97	284.385	5	↓ MOL2 SDF SMILES Flexibase

70308452

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-1-cyclopentylethyl]-2-hydrazino-pyridine-3-sulfonamide N-[(1R)-1-cyclopentylethyl]-2-hy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.41	2.02	-10.74	4	6	0	97	284.385	5	↓ MOL2 SDF SMILES Flexibase

70309165

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-N-[(1S)-1-cyclopentylethyl]pyridine-3-sulfonamide 5-bromo-N-[(1S)-1-cyclopentyleth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.00	3.61	-7.18	1	4	0	59	333.251	4	↓ MOL2 SDF SMILES Flexibase

70309166

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-bromo-N-[(1R)-1-cyclopentylethyl]pyridine-3-sulfonamide 5-bromo-N-[(1R)-1-cyclopentyleth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.00	3.4	-7.36	1	4	0	59	333.251	4	↓ MOL2 SDF SMILES Flexibase

70309187

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-5-(3-hydroxyprop-1-ynyl)pyridine-3-sulfonamide N-[(1S)-1-cyclopentylethyl]-5-(3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.60	1.79	-11.65	2	5	0	79	308.403	4	↓ MOL2 SDF SMILES Flexibase

70309188

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-1-cyclopentylethyl]-5-(3-hydroxyprop-1-ynyl)pyridine-3-sulfonamide N-[(1R)-1-cyclopentylethyl]-5-(3…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.60	1.59	-11.45	2	5	0	79	308.403	4	↓ MOL2 SDF SMILES Flexibase

70309199

Analogs

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Popular Name: 5-(3-aminoprop-1-ynyl)-N-[(1S)-1-cyclopentylethyl]pyridine-3-sulfonamide 5-(3-aminoprop-1-ynyl)-N-[(1S)-1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.03	2.5	-55.3	4	5	1	87	308.427	4	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	1.03	2.09	-9.29	3	5	0	85	307.419	4	↓ MOL2 SDF SMILES Flexibase

70309200

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-(3-aminoprop-1-ynyl)-N-[(1R)-1-cyclopentylethyl]pyridine-3-sulfonamide 5-(3-aminoprop-1-ynyl)-N-[(1R)-1…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.03	2.3	-56.57	4	5	1	87	308.427	4	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	1.03	1.89	-9.42	3	5	0	85	307.419	4	↓ MOL2 SDF SMILES Flexibase

70309247

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-6-(methylamino)pyridine-3-sulfonamide N-[(1S)-1-cyclopentylethyl]-6-(m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.25	2.64	-9.58	2	5	0	71	283.397	5	↓ MOL2 SDF SMILES Flexibase

70309248

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-6-(methylamino)pyridine-3-sulfonamide N-[(1R)-1-cyclopentylethyl]-6-(m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.25	2.44	-9.82	2	5	0	71	283.397	5	↓ MOL2 SDF SMILES Flexibase

70309249

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-2-(propylamino)pyridine-3-sulfonamide N-[(1S)-1-cyclopentylethyl]-2-(p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.91	4.69	-8.96	2	5	0	71	311.451	7	↓ MOL2 SDF SMILES Flexibase

70309250

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-2-(propylamino)pyridine-3-sulfonamide N-[(1R)-1-cyclopentylethyl]-2-(p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.91	4.97	-9.23	2	5	0	71	311.451	7	↓ MOL2 SDF SMILES Flexibase

70309255

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-2-(methylamino)pyridine-3-sulfonamide N-[(1S)-1-cyclopentylethyl]-2-(m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.03	3.03	-9.23	2	5	0	71	283.397	5	↓ MOL2 SDF SMILES Flexibase

70309256

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-2-(methylamino)pyridine-3-sulfonamide N-[(1R)-1-cyclopentylethyl]-2-(m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.03	3.13	-9.65	2	5	0	71	283.397	5	↓ MOL2 SDF SMILES Flexibase

70309259

Analogs

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Popular Name: 2-amino-N-[(1S)-1-cyclopentylethyl]pyridine-3-sulfonamide 2-amino-N-[(1S)-1-cyclopentyleth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.65	1.78	-9.08	3	5	0	85	269.37	4	↓ MOL2 SDF SMILES Flexibase

70309260

Analogs

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Popular Name: 2-amino-N-[(1R)-1-cyclopentylethyl]pyridine-3-sulfonamide 2-amino-N-[(1R)-1-cyclopentyleth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.65	2.18	-9.5	3	5	0	85	269.37	4	↓ MOL2 SDF SMILES Flexibase

70309265

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-6-(ethylamino)pyridine-3-sulfonamide N-[(1S)-1-cyclopentylethyl]-6-(e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.62	3.44	-8.9	2	5	0	71	297.424	6	↓ MOL2 SDF SMILES Flexibase

70309266

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-6-(ethylamino)pyridine-3-sulfonamide N-[(1R)-1-cyclopentylethyl]-6-(e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.62	3.21	-9.06	2	5	0	71	297.424	6	↓ MOL2 SDF SMILES Flexibase

70309267

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-2-(ethylamino)pyridine-3-sulfonamide N-[(1S)-1-cyclopentylethyl]-2-(e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.40	3.92	-9.09	2	5	0	71	297.424	6	↓ MOL2 SDF SMILES Flexibase

70309268

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-2-(ethylamino)pyridine-3-sulfonamide N-[(1R)-1-cyclopentylethyl]-2-(e…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.40	4.21	-9.42	2	5	0	71	297.424	6	↓ MOL2 SDF SMILES Flexibase

70309275

Analogs

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Popular Name: N-[(1S)-1-cyclopentylethyl]-6-(propylamino)pyridine-3-sulfonamide N-[(1S)-1-cyclopentylethyl]-6-(p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.12	4.2	-8.64	2	5	0	71	311.451	7	↓ MOL2 SDF SMILES Flexibase

70309276

Analogs

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Popular Name: N-[(1R)-1-cyclopentylethyl]-6-(propylamino)pyridine-3-sulfonamide N-[(1R)-1-cyclopentylethyl]-6-(p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.12	3.98	-8.79	2	5	0	71	311.451	7	↓ MOL2 SDF SMILES Flexibase

70309283

Analogs

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Popular Name: 5-bromo-N-[(1S)-1-cyclopentylethyl]-2-(ethylamino)pyridine-3-sulfonamide 5-bromo-N-[(1S)-1-cyclopentyleth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.36	4.51	-7.55	2	5	0	71	376.32	6	↓ MOL2 SDF SMILES Flexibase

70309284

Analogs

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Popular Name: 5-bromo-N-[(1R)-1-cyclopentylethyl]-2-(ethylamino)pyridine-3-sulfonamide 5-bromo-N-[(1R)-1-cyclopentyleth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.36	4.8	-7.82	2	5	0	71	376.32	6	↓ MOL2 SDF SMILES Flexibase

70309293

Analogs

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Popular Name: 5-bromo-N-[(1S)-1-cyclopentylethyl]-2-(methylamino)pyridine-3-sulfonamide 5-bromo-N-[(1S)-1-cyclopentyleth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.98	3.62	-7.79	2	5	0	71	362.293	5	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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SQL Query Was

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