ZINC 12

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.27	3.41	-55.94	2	6	1	66	296.391	2	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	-0.27	5.64	-103.76	3	6	2	68	297.399	2	↓ MOL2 SDF SMILES Flexibase

54670542

Analogs

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Popular Name: 2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]-N-[3-(trifluoromethoxy)phenyl]acetamide 2-[(3S)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.67	4.22	-18.97	1	6	0	68	346.305	6	↓ MOL2 SDF SMILES Flexibase

54670544

Analogs

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Popular Name: 2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]-N-[3-(trifluoromethoxy)phenyl]acetamide 2-[(3R)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.67	4.54	-15.32	1	6	0	68	346.305	6	↓ MOL2 SDF SMILES Flexibase

54670546

Analogs

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Popular Name: N-(2-chlorophenyl)-2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-(2-chlorophenyl)-2-[(3S)-4-eth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.36	5.3	-12.61	1	5	0	59	296.754	4	↓ MOL2 SDF SMILES Flexibase

54670548

Analogs

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Popular Name: N-(2-chlorophenyl)-2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-(2-chlorophenyl)-2-[(3R)-4-eth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.36	5.34	-12.14	1	5	0	59	296.754	4	↓ MOL2 SDF SMILES Flexibase

54670550

Analogs

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Popular Name: 2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]-N-(2-methoxyphenyl)acetamide 2-[(3S)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	3.82	-16.48	1	6	0	68	292.335	5	↓ MOL2 SDF SMILES Flexibase

54670551

Analogs

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Popular Name: 2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]-N-(2-methoxyphenyl)acetamide 2-[(3R)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.73	4.15	-14.1	1	6	0	68	292.335	5	↓ MOL2 SDF SMILES Flexibase

54670554

Analogs

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Popular Name: 2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]-N-(4-methyl-3-nitro-phenyl)acetamide 2-[(3S)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.06	6.01	-21.16	1	8	0	104	321.333	5	↓ MOL2 SDF SMILES Flexibase

54670555

Analogs

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Popular Name: 2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]-N-(4-methyl-3-nitro-phenyl)acetamide 2-[(3R)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.06	6.14	-21.53	1	8	0	104	321.333	5	↓ MOL2 SDF SMILES Flexibase

54670557

Analogs

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Popular Name: N-(3-chloro-2-methyl-phenyl)-2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-(3-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.76	5.96	-12.99	1	5	0	59	310.781	4	↓ MOL2 SDF SMILES Flexibase

54670560

Analogs

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Popular Name: N-(3-chloro-2-methyl-phenyl)-2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-(3-chloro-2-methyl-phenyl)-2-[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.76	6.02	-12.8	1	5	0	59	310.781	4	↓ MOL2 SDF SMILES Flexibase

54670562

Analogs

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Popular Name: N-benzyl-2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-benzyl-2-[(3S)-4-ethyl-2-oxo-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.43	4.59	-15.18	1	5	0	59	276.336	5	↓ MOL2 SDF SMILES Flexibase

54670563

Analogs

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Popular Name: N-benzyl-2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-benzyl-2-[(3R)-4-ethyl-2-oxo-m…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.43	4.59	-15.14	1	5	0	59	276.336	5	↓ MOL2 SDF SMILES Flexibase

54670565

Analogs

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Popular Name: 2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]-N-phenethyl-acetamide 2-[(3S)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.83	5.36	-17.56	1	5	0	59	290.363	6	↓ MOL2 SDF SMILES Flexibase

54670567

Analogs

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Popular Name: 2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]-N-phenethyl-acetamide 2-[(3R)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.83	5.75	-14.83	1	5	0	59	290.363	6	↓ MOL2 SDF SMILES Flexibase

54670572

Analogs

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Popular Name: 2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]-N-(2-phenylsulfanylphenyl)acetamide 2-[(3S)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.64	8.78	-15.73	1	5	0	59	370.474	6	↓ MOL2 SDF SMILES Flexibase

54670574

Analogs

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Popular Name: 2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]-N-(2-phenylsulfanylphenyl)acetamide 2-[(3R)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.64	9.03	-13.55	1	5	0	59	370.474	6	↓ MOL2 SDF SMILES Flexibase

54670575

Analogs

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Popular Name: 2-[(3S)-4-benzyl-2-oxo-morpholin-3-yl]-N-(2-phenylsulfanylphenyl)acetamide 2-[(3S)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.67	11.89	-14.64	1	5	0	59	432.545	7	↓ MOL2 SDF SMILES Flexibase

54670577

Analogs

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Popular Name: 2-[(3R)-4-benzyl-2-oxo-morpholin-3-yl]-N-(2-phenylsulfanylphenyl)acetamide 2-[(3R)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.67	11.63	-16.57	1	5	0	59	432.545	7	↓ MOL2 SDF SMILES Flexibase

54670579

Analogs

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Popular Name: 2-[(3S)-4-benzyl-2-oxo-morpholin-3-yl]-N-(1-naphthyl)acetamide 2-[(3S)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.91	9.97	-15.78	1	5	0	59	374.44	5	↓ MOL2 SDF SMILES Flexibase

54670581

Analogs

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Popular Name: 2-[(3R)-4-benzyl-2-oxo-morpholin-3-yl]-N-(1-naphthyl)acetamide 2-[(3R)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.91	10.06	-15.67	1	5	0	59	374.44	5	↓ MOL2 SDF SMILES Flexibase

54670582

Analogs

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Popular Name: 2-[(3R)-4-benzyl-2-oxo-morpholin-3-yl]-N-(p-tolyl)acetamide 2-[(3R)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.20	8.2	-18.37	1	5	0	59	338.407	5	↓ MOL2 SDF SMILES Flexibase

54670583

Analogs

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Popular Name: 2-[(3S)-4-benzyl-2-oxo-morpholin-3-yl]-N-(p-tolyl)acetamide 2-[(3S)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.20	8.07	-18.04	1	5	0	59	338.407	5	↓ MOL2 SDF SMILES Flexibase

54670584

Analogs

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Popular Name: 2-[(3R)-4-benzyl-2-oxo-morpholin-3-yl]-N-(4-ethylphenyl)acetamide 2-[(3R)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.66	9.11	-14.62	1	5	0	59	352.434	6	↓ MOL2 SDF SMILES Flexibase

54670585

Analogs

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Popular Name: 2-[(3S)-4-benzyl-2-oxo-morpholin-3-yl]-N-(4-ethylphenyl)acetamide 2-[(3S)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.66	9.11	-14.54	1	5	0	59	352.434	6	↓ MOL2 SDF SMILES Flexibase

54670586

Analogs

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Popular Name: 2-[(3S)-4-benzyl-2-oxo-morpholin-3-yl]-N-(4-phenoxyphenyl)acetamide 2-[(3S)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.50	10.63	-16.85	1	6	0	68	416.477	7	↓ MOL2 SDF SMILES Flexibase

54670589

Analogs

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Popular Name: 2-[(3R)-4-benzyl-2-oxo-morpholin-3-yl]-N-(4-phenoxyphenyl)acetamide 2-[(3R)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.50	10.07	-16.32	1	6	0	68	416.477	7	↓ MOL2 SDF SMILES Flexibase

54670590

Analogs

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Popular Name: 2-[(3S)-4-benzyl-2-oxo-morpholin-3-yl]-N-(3-nitrophenyl)acetamide 2-[(3S)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.68	8.26	-21.6	1	8	0	104	369.377	6	↓ MOL2 SDF SMILES Flexibase

54670591

Analogs

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Popular Name: 2-[(3R)-4-benzyl-2-oxo-morpholin-3-yl]-N-(3-nitrophenyl)acetamide 2-[(3R)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.68	8.37	-21.32	1	8	0	104	369.377	6	↓ MOL2 SDF SMILES Flexibase

54670592

Analogs

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Popular Name: 2-[(3R)-4-benzyl-2-oxo-morpholin-3-yl]-N-(3,4-dimethylphenyl)acetamide 2-[(3R)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.57	8.75	-18.46	1	5	0	59	352.434	5	↓ MOL2 SDF SMILES Flexibase

54670593

Analogs

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Popular Name: 2-[(3S)-4-benzyl-2-oxo-morpholin-3-yl]-N-(3,4-dimethylphenyl)acetamide 2-[(3S)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.57	8.9	-14.85	1	5	0	59	352.434	5	↓ MOL2 SDF SMILES Flexibase

54670595

Analogs

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Popular Name: 2-[(3R)-4-benzyl-2-oxo-morpholin-3-yl]-N-(3-chloro-4-methyl-phenyl)acetamide 2-[(3R)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.80	8.63	-20.02	1	5	0	59	372.852	5	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.77	8.46	-58.47	2	5	1	63	373.86	5	↓ MOL2 SDF SMILES Flexibase

54670597

Analogs

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Popular Name: 2-[(3S)-4-benzyl-2-oxo-morpholin-3-yl]-N-(3-chloro-4-methyl-phenyl)acetamide 2-[(3S)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.80	8.5	-16.8	1	5	0	59	372.852	5	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.77	8.36	-59.28	2	5	1	63	373.86	5	↓ MOL2 SDF SMILES Flexibase

54670598

Analogs

12652917
12652921

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Popular Name: 2-[(3R)-4-benzyl-2-oxo-morpholin-3-yl]-N-(3,5-dimethylphenyl)acetamide 2-[(3R)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.57	8.86	-18.36	1	5	0	59	352.434	5	↓ MOL2 SDF SMILES Flexibase

54670599

Analogs

12652917
12652921

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Popular Name: 2-[(3S)-4-benzyl-2-oxo-morpholin-3-yl]-N-(3,5-dimethylphenyl)acetamide 2-[(3S)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.57	9.01	-14.85	1	5	0	59	352.434	5	↓ MOL2 SDF SMILES Flexibase

54670782

Analogs

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Popular Name: 2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]-N-(1-naphthyl)acetamide 2-[(3S)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.89	6.84	-17.96	1	5	0	59	312.369	4	↓ MOL2 SDF SMILES Flexibase

54670783

Analogs

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Popular Name: 2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]-N-(1-naphthyl)acetamide 2-[(3R)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.89	6.84	-17.81	1	5	0	59	312.369	4	↓ MOL2 SDF SMILES Flexibase

54670784

Analogs

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Popular Name: 2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]-N-(3,4,5-trimethoxyphenyl)acetamide 2-[(3S)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.36	3.57	-21.22	1	8	0	86	352.387	7	↓ MOL2 SDF SMILES Flexibase

54670786

Analogs

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Popular Name: 2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]-N-(3,4,5-trimethoxyphenyl)acetamide 2-[(3R)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.36	3.61	-21.72	1	8	0	86	352.387	7	↓ MOL2 SDF SMILES Flexibase

54670788

Analogs

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Popular Name: 2-[(3S)-4-benzyl-2-oxo-morpholin-3-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]acetamide 2-[(3S)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.25	8.97	-13.92	1	5	0	59	426.822	6	↓ MOL2 SDF SMILES Flexibase

54670789

Analogs

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Popular Name: 2-[(3R)-4-benzyl-2-oxo-morpholin-3-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]acetamide 2-[(3R)-4-benzyl-2-oxo-morpholin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.25	8.84	-16.87	1	5	0	59	426.822	6	↓ MOL2 SDF SMILES Flexibase

54670977

Analogs

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Popular Name: N-(2-ethoxyphenyl)-2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-(2-ethoxyphenyl)-2-[(3S)-4-eth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.11	4.76	-16.18	1	6	0	68	306.362	6	↓ MOL2 SDF SMILES Flexibase

54670979

Analogs

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Popular Name: N-(2-ethoxyphenyl)-2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-(2-ethoxyphenyl)-2-[(3R)-4-eth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.11	5.09	-13.79	1	6	0	68	306.362	6	↓ MOL2 SDF SMILES Flexibase

54670981

Analogs

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Popular Name: 2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]-N-(2-nitrophenyl)acetamide 2-[(3S)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.64	5.49	-15.98	1	8	0	104	307.306	5	↓ MOL2 SDF SMILES Flexibase

54670983

Analogs

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Popular Name: 2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]-N-(2-nitrophenyl)acetamide 2-[(3R)-4-ethyl-2-oxo-morpholin-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.64	5.8	-15.41	1	8	0	104	307.306	5	↓ MOL2 SDF SMILES Flexibase

54670985

Analogs

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Popular Name: N-(2,5-dimethylphenyl)-2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-(2,5-dimethylphenyl)-2-[(3S)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.55	6.19	-14.89	1	5	0	59	290.363	4	↓ MOL2 SDF SMILES Flexibase

54670987

Analogs

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Popular Name: N-(2,5-dimethylphenyl)-2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-(2,5-dimethylphenyl)-2-[(3R)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.55	6.25	-14.23	1	5	0	59	290.363	4	↓ MOL2 SDF SMILES Flexibase

54670989

Analogs

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Popular Name: N-(2,5-dichlorophenyl)-2-[(3S)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-(2,5-dichlorophenyl)-2-[(3S)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.01	5.81	-12.52	1	5	0	59	331.199	4	↓ MOL2 SDF SMILES Flexibase

54670991

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2,5-dichlorophenyl)-2-[(3R)-4-ethyl-2-oxo-morpholin-3-yl]acetamide N-(2,5-dichlorophenyl)-2-[(3R)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.01	5.86	-12.28	1	5	0	59	331.199	4	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 11481 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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