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ZINC Item

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22723577

Analogs

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Popular Name: N-benzyl-2-[4-(3-fluorophenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-benzyl-2-[4-(3-fluorophenyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.39	9.15	-23.27	1	6	0	73	353.353	5	↓ MOL2 SDF SMILES Flexibase

22723608

Analogs

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Popular Name: N-benzyl-2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-benzyl-2-[4-(2-methoxyphenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.26	8.59	-24.84	1	7	0	82	365.389	6	↓ MOL2 SDF SMILES Flexibase

22723610

Analogs

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Popular Name: N-benzyl-2-[4-(o-tolyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-benzyl-2-[4-(o-tolyl)-2,3-diox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.65	10.12	-23.1	1	6	0	73	349.39	5	↓ MOL2 SDF SMILES Flexibase

22723614

Analogs

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Popular Name: N-benzyl-2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-benzyl-2-[4-(4-ethoxyphenyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.47	9.38	-22.99	1	7	0	82	379.416	7	↓ MOL2 SDF SMILES Flexibase

22723626

Analogs

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Popular Name: N-benzyl-2-[4-(2-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-benzyl-2-[4-(2-ethoxyphenyl)-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.64	9.52	-24.76	1	7	0	82	379.416	7	↓ MOL2 SDF SMILES Flexibase

22723814

Analogs

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Popular Name: N-[(2-chlorophenyl)methyl]-2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(2-chlorophenyl)methyl]-2-[4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.89	9.01	-24.17	1	7	0	82	399.834	6	↓ MOL2 SDF SMILES Flexibase

22723816

Analogs

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Popular Name: N-[(2-chlorophenyl)methyl]-2-[4-(o-tolyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(2-chlorophenyl)methyl]-2-[4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.28	10.54	-22.4	1	6	0	73	383.835	5	↓ MOL2 SDF SMILES Flexibase

22723820

Analogs

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Popular Name: N-[(2-chlorophenyl)methyl]-2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(2-chlorophenyl)methyl]-2-[4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.10	9.8	-22.26	1	7	0	82	413.861	7	↓ MOL2 SDF SMILES Flexibase

22723832

Analogs

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Popular Name: N-[(2-chlorophenyl)methyl]-2-[4-(2-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(2-chlorophenyl)methyl]-2-[4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.27	9.93	-24.08	1	7	0	82	413.861	7	↓ MOL2 SDF SMILES Flexibase

67255973

Analogs

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Popular Name: 2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-(p-tolylmethyl)acetamide 2-[4-(4-ethoxyphenyl)-2,3-dioxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.92	10.06	-22.97	1	7	0	82	393.443	7	↓ MOL2 SDF SMILES Flexibase

67256048

Analogs

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Popular Name: 2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide 2-[4-(4-ethoxyphenyl)-2,3-dioxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.64	9.45	-23.73	1	7	0	82	397.406	7	↓ MOL2 SDF SMILES Flexibase

67256083

Analogs

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Popular Name: 2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(4-methoxyphenyl)methyl]acetamide 2-[4-(4-ethoxyphenyl)-2,3-dioxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.53	8.68	-24.45	1	8	0	92	409.442	8	↓ MOL2 SDF SMILES Flexibase

67256087

Analogs

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Popular Name: 2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(3-methoxyphenyl)methyl]acetamide 2-[4-(4-ethoxyphenyl)-2,3-dioxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.51	8.68	-23.76	1	8	0	92	409.442	8	↓ MOL2 SDF SMILES Flexibase

67256090

Analogs

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Popular Name: N-[(4-chlorophenyl)methyl]-2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(4-chlorophenyl)methyl]-2-[4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.15	9.9	-23.18	1	7	0	82	413.861	7	↓ MOL2 SDF SMILES Flexibase

67256098

Analogs

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Popular Name: N-[(2,3-dimethoxyphenyl)methyl]-2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(2,3-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.29	8.62	-24.12	1	9	0	101	439.468	9	↓ MOL2 SDF SMILES Flexibase

67256145

Analogs

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Popular Name: N-[(3,4-dimethoxyphenyl)methyl]-2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(3,4-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.12	8.58	-26.28	1	9	0	101	439.468	9	↓ MOL2 SDF SMILES Flexibase

67256152

Analogs

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Popular Name: N-[(3-chloro-4-fluoro-phenyl)methyl]-2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(3-chloro-4-fluoro-phenyl)met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.24	9.94	-23.93	1	7	0	82	431.851	7	↓ MOL2 SDF SMILES Flexibase

67256181

Analogs

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Popular Name: N-[(2,4-difluorophenyl)methyl]-2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(2,4-difluorophenyl)methyl]-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.73	9.47	-22.7	1	7	0	82	415.396	7	↓ MOL2 SDF SMILES Flexibase

67256202

Analogs

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Popular Name: 2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]acetamide 2-[4-(4-ethoxyphenyl)-2,3-dioxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.09	9.54	-24.26	1	8	0	92	423.469	8	↓ MOL2 SDF SMILES Flexibase

67256206

Analogs

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Popular Name: 2-[4-(4-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(1R)-1-(4-methoxyphenyl)ethyl]acetamide 2-[4-(4-ethoxyphenyl)-2,3-dioxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.09	9.53	-25.14	1	8	0	92	423.469	8	↓ MOL2 SDF SMILES Flexibase

67256295

Analogs

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Popular Name: 2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-(p-tolylmethyl)acetamide 2-[4-(2-methoxyphenyl)-2,3-dioxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.71	9.27	-24.79	1	7	0	82	379.416	6	↓ MOL2 SDF SMILES Flexibase

67256358

Analogs

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Popular Name: N-[(4-fluorophenyl)methyl]-2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(4-fluorophenyl)methyl]-2-[4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.42	8.66	-25.61	1	7	0	82	383.379	6	↓ MOL2 SDF SMILES Flexibase

67256396

Analogs

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Popular Name: 2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(4-methoxyphenyl)methyl]acetamide 2-[4-(2-methoxyphenyl)-2,3-dioxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.32	7.89	-25.91	1	8	0	92	395.415	7	↓ MOL2 SDF SMILES Flexibase

67256398

Analogs

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Popular Name: 2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(3-methoxyphenyl)methyl]acetamide 2-[4-(2-methoxyphenyl)-2,3-dioxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.29	7.89	-25.54	1	8	0	92	395.415	7	↓ MOL2 SDF SMILES Flexibase

67256402

Analogs

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Popular Name: N-[(4-chlorophenyl)methyl]-2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(4-chlorophenyl)methyl]-2-[4-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.94	9.11	-25.07	1	7	0	82	399.834	6	↓ MOL2 SDF SMILES Flexibase

67256413

Analogs

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Popular Name: N-[(2,3-dimethoxyphenyl)methyl]-2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(2,3-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.08	7.83	-25.98	1	9	0	101	425.441	8	↓ MOL2 SDF SMILES Flexibase

67256456

Analogs

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Popular Name: N-[(3,4-dimethoxyphenyl)methyl]-2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(3,4-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.91	7.79	-28.16	1	9	0	101	425.441	8	↓ MOL2 SDF SMILES Flexibase

67256509

Analogs

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Popular Name: N-[(2,4-difluorophenyl)methyl]-2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(2,4-difluorophenyl)methyl]-2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.52	8.68	-24.55	1	7	0	82	401.369	6	↓ MOL2 SDF SMILES Flexibase

67256522

Analogs

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Popular Name: 2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]acetamide 2-[4-(2-methoxyphenyl)-2,3-dioxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.88	8.74	-26.94	1	8	0	92	409.442	7	↓ MOL2 SDF SMILES Flexibase

67256525

Analogs

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Popular Name: 2-[4-(2-methoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(1R)-1-(4-methoxyphenyl)ethyl]acetamide 2-[4-(2-methoxyphenyl)-2,3-dioxo…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.88	8.74	-26.06	1	8	0	92	409.442	7	↓ MOL2 SDF SMILES Flexibase

67256580

Analogs

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Popular Name: 2-[4-(2-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-(p-tolylmethyl)acetamide 2-[4-(2-ethoxyphenyl)-2,3-dioxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.08	10.19	-24.73	1	7	0	82	393.443	7	↓ MOL2 SDF SMILES Flexibase

67256665

Analogs

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Popular Name: 2-[4-(2-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide 2-[4-(2-ethoxyphenyl)-2,3-dioxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.80	9.59	-25.49	1	7	0	82	397.406	7	↓ MOL2 SDF SMILES Flexibase

67256689

Analogs

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Popular Name: 2-[4-(2-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(4-methoxyphenyl)methyl]acetamide 2-[4-(2-ethoxyphenyl)-2,3-dioxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.69	8.82	-26.22	1	8	0	92	409.442	8	↓ MOL2 SDF SMILES Flexibase

67256695

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Popular Name: N-[(2,3-dimethoxyphenyl)methyl]-2-[4-(2-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(2,3-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.46	8.76	-25.89	1	9	0	101	439.468	9	↓ MOL2 SDF SMILES Flexibase

67256741

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Popular Name: N-[(3,4-dimethoxyphenyl)methyl]-2-[4-(2-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]acetamide N-[(3,4-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.28	8.72	-28.05	1	9	0	101	439.468	9	↓ MOL2 SDF SMILES Flexibase

67256807

Analogs

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Popular Name: 2-[4-(2-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]acetamide 2-[4-(2-ethoxyphenyl)-2,3-dioxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.25	9.66	-26.01	1	8	0	92	423.469	8	↓ MOL2 SDF SMILES Flexibase

67256811

Analogs

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Popular Name: 2-[4-(2-ethoxyphenyl)-2,3-dioxo-pyrazin-1-yl]-N-[(1R)-1-(4-methoxyphenyl)ethyl]acetamide 2-[4-(2-ethoxyphenyl)-2,3-dioxo-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.25	9.66	-26.86	1	8	0	92	423.469	8	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
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Structural Results Found: (before additional filtering)

SQL Query Was

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