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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

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Popular Name: 2-chloro-N-ethyl-4-methyl-N-(m-tolyl)thiazole-5-sulfonamide 2-chloro-N-ethyl-4-methyl-N-(m-t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.99 5.47 -8.79 0 4 0 50 330.862 4 ↓

Analogs

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Popular Name: 2-chloro-N-ethyl-N-(m-tolyl)thiazole-5-sulfonamide 2-chloro-N-ethyl-N-(m-tolyl)thia…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.77 4.85 -7.82 0 4 0 50 316.835 4 ↓

Analogs

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Popular Name: 2-chloro-N-(2-cyano-3-fluoro-phenyl)-4-methyl-thiazole-5-sulfonamide 2-chloro-N-(2-cyano-3-fluoro-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.77 3.24 -34.6 0 5 -1 85 330.773 3 ↓

Analogs

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Popular Name: 2-chloro-N-(2-cyano-3-fluoro-phenyl)thiazole-5-sulfonamide 2-chloro-N-(2-cyano-3-fluoro-phe…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.55 2.59 -34.15 0 5 -1 85 316.746 3 ↓

Analogs

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Popular Name: 2-chloro-N-(4-dimethylaminophenyl)-4-methyl-thiazole-5-sulfonamide 2-chloro-N-(4-dimethylaminopheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 3.13 -9.01 1 5 0 62 331.85 4 ↓
Mid Mid (pH 6-8) 3.05 3.15 -41.02 0 5 -1 64 330.842 4 ↓

Analogs

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Popular Name: 2-chloro-N-(4-dimethylaminophenyl)thiazole-5-sulfonamide 2-chloro-N-(4-dimethylaminopheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 2.48 -8.2 1 5 0 62 317.823 4 ↓
Mid Mid (pH 6-8) 2.83 2.51 -39.98 0 5 -1 64 316.815 4 ↓

Analogs

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Popular Name: 4-[(4-methyl-2-oxo-3H-thiazol-5-yl)sulfonylamino]benzoic 4-[(4-methyl-2-oxo-3H-thiazol-5-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.96 -0.54 -97.57 1 7 -2 122 312.328 4 ↓
Hi High (pH 8-9.5) 1.96 -0.49 -165.41 0 7 -3 124 311.32 4 ↓
Mid Mid (pH 6-8) 1.50 1.64 -100.96 1 7 -2 121 312.328 4 ↓

Analogs

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Popular Name: 2-chloro-N-[2-fluoro-5-(trifluoromethyl)phenyl]thiazole-5-sulfonamide 2-chloro-N-[2-fluoro-5-(trifluor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.71 3.29 -35.58 0 4 -1 61 359.733 4 ↓

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.78 3.07 -49.55 0 8 -1 106 385.443 7 ↓
Lo Low (pH 4.5-6) 1.78 3.48 -43.77 1 8 0 107 386.451 7 ↓

Analogs

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Popular Name: 2-chloro-4-methyl-N-[2-[(1R)-1-methylpropyl]phenyl]thiazole-5-sulfonamide 2-chloro-4-methyl-N-[2-[(1R)-1-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.28 5.38 -40.53 0 4 -1 61 343.881 5 ↓
Mid Mid (pH 6-8) 4.28 5.26 -7.91 1 4 0 59 344.889 5 ↓

Analogs

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Popular Name: 2-chloro-4-methyl-N-[2-[(1S)-1-methylpropyl]phenyl]thiazole-5-sulfonamide 2-chloro-4-methyl-N-[2-[(1S)-1-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.28 5.38 -40.55 0 4 -1 61 343.881 5 ↓
Mid Mid (pH 6-8) 4.28 5.27 -7.85 1 4 0 59 344.889 5 ↓

Analogs

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Popular Name: 2-chloro-N-[2-[(1R)-1-methylpropyl]phenyl]thiazole-5-sulfonamide 2-chloro-N-[2-[(1R)-1-methylprop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.06 4.79 -38.77 0 4 -1 61 329.854 5 ↓
Lo Low (pH 4.5-6) 4.06 4.79 -7.07 1 4 0 59 330.862 5 ↓

Analogs

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Popular Name: 2-chloro-N-[2-[(1S)-1-methylpropyl]phenyl]thiazole-5-sulfonamide 2-chloro-N-[2-[(1S)-1-methylprop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.06 4.79 -38.78 0 4 -1 61 329.854 5 ↓
Lo Low (pH 4.5-6) 4.06 4.79 -7 1 4 0 59 330.862 5 ↓

Analogs

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Popular Name: 2-chloro-N-(4-methoxy-3-methyl-phenyl)thiazole-5-sulfonamide 2-chloro-N-(4-methoxy-3-methyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.16 2.15 -38.35 0 5 -1 70 317.799 4 ↓
Mid Mid (pH 6-8) 3.16 2.12 -8.4 1 5 0 68 318.807 4 ↓

Analogs

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Popular Name: 2-chloro-N-(4-methoxy-3-methyl-phenyl)-4-methyl-thiazole-5-sulfonamide 2-chloro-N-(4-methoxy-3-methyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.38 2.74 -39.97 0 5 -1 70 331.826 4 ↓
Mid Mid (pH 6-8) 3.38 2.66 -9.25 1 5 0 68 332.834 4 ↓

Analogs

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Popular Name: 2-chloro-N-[2-[(1S)-1-hydroxyethyl]phenyl]thiazole-5-sulfonamide 2-chloro-N-[2-[(1S)-1-hydroxyeth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.24 0.41 -37.59 1 5 -1 81 317.799 4 ↓

Analogs

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Popular Name: 2-chloro-N-[2-[(1R)-1-hydroxyethyl]phenyl]thiazole-5-sulfonamide 2-chloro-N-[2-[(1R)-1-hydroxyeth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.24 0.41 -37.69 1 5 -1 81 317.799 4 ↓

Analogs

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Popular Name: 2-chloro-N-[2-[(1R)-1-hydroxyethyl]phenyl]-4-methyl-thiazole-5-sulfonamide 2-chloro-N-[2-[(1R)-1-hydroxyeth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.46 1.06 -38.89 1 5 -1 81 331.826 4 ↓

Analogs

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Popular Name: 2-chloro-N-[2-[(1S)-1-hydroxyethyl]phenyl]-4-methyl-thiazole-5-sulfonamide 2-chloro-N-[2-[(1S)-1-hydroxyeth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.46 1.06 -38.85 1 5 -1 81 331.826 4 ↓

Analogs

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Popular Name: N-(5-bromo-2-methoxy-phenyl)-2-chloro-thiazole-5-sulfonamide N-(5-bromo-2-methoxy-phenyl)-2-c…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.52 2.07 -39.52 0 5 -1 70 382.668 4 ↓

Analogs

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Popular Name: N-(5-bromo-2-methoxy-phenyl)-2-chloro-4-methyl-thiazole-5-sulfonamide N-(5-bromo-2-methoxy-phenyl)-2-c…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.74 2.73 -40.59 0 5 -1 70 396.695 4 ↓

Analogs

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Popular Name: 2-chloro-N-(4-fluoro-2-methoxy-phenyl)thiazole-5-sulfonamide 2-chloro-N-(4-fluoro-2-methoxy-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.87 1.51 -36.41 0 5 -1 70 321.762 4 ↓

Analogs

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Popular Name: 2-chloro-N-(4-fluoro-2-methoxy-phenyl)-4-methyl-thiazole-5-sulfonamide 2-chloro-N-(4-fluoro-2-methoxy-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 2.18 -37.32 0 5 -1 70 335.789 4 ↓

Parameters Provided:

ring.id = 11952
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 11952 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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