ZINC 12

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ZINC Item

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54419672

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-(4-hydroxycyclohexyl)-1,2,5-oxadiazole-3-carboxamide 4-amino-N-(4-hydroxycyclohexyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.28	-1.86	-6.93	4	7	0	114	226.236	2	↓ MOL2 SDF SMILES Flexibase

54419810

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,2R,3R)-2,3-dimethylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,2R,3R)-2,3-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.82	2.41	-4.52	3	6	0	94	238.291	2	↓ MOL2 SDF SMILES Flexibase

54419812

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,2R,3S)-2,3-dimethylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,2R,3S)-2,3-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.82	3.22	-4.5	3	6	0	94	238.291	2	↓ MOL2 SDF SMILES Flexibase

54419814

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,2R,3R)-2,3-dimethylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2R,3R)-2,3-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.82	2.58	-4.59	3	6	0	94	238.291	2	↓ MOL2 SDF SMILES Flexibase

54419816

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,2R,3S)-2,3-dimethylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2R,3S)-2,3-dimeth…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.82	2.8	-4.57	3	6	0	94	238.291	2	↓ MOL2 SDF SMILES Flexibase

54419818

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-cyclohexyl-N-ethyl-1,2,5-oxadiazole-3-carboxamide 4-amino-N-cyclohexyl-N-ethyl-1,2…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	4.69	-5.04	2	6	0	85	238.291	3	↓ MOL2 SDF SMILES Flexibase

54420333

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,3R)-3-hydroxycyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,3R)-3-hydroxycycl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.04	-1.86	-6.4	4	7	0	114	226.236	2	↓ MOL2 SDF SMILES Flexibase

54420337

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,3R)-3-hydroxycyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,3R)-3-hydroxycycl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.04	-1.72	-7.07	4	7	0	114	226.236	2	↓ MOL2 SDF SMILES Flexibase

54420339

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,3S)-3-hydroxycyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,3S)-3-hydroxycycl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.04	-1.45	-6.18	4	7	0	114	226.236	2	↓ MOL2 SDF SMILES Flexibase

54420341

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,3S)-3-hydroxycyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,3S)-3-hydroxycycl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.04	-1.86	-6.44	4	7	0	114	226.236	2	↓ MOL2 SDF SMILES Flexibase

54420482

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-(4-carbamoylcyclohexyl)-1,2,5-oxadiazole-3-carboxamide 4-amino-N-(4-carbamoylcyclohexyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.53	-1.85	-11.68	5	8	0	137	253.262	3	↓ MOL2 SDF SMILES Flexibase

54420485

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,3R)-3-(2,2,2-trif…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.50	1.9	-8.03	3	7	0	103	308.26	5	↓ MOL2 SDF SMILES Flexibase

54420489

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,3R)-3-(2,2,2-trifluoroethoxy)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,3R)-3-(2,2,2-trif…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.50	2.33	-7.59	3	7	0	103	308.26	5	↓ MOL2 SDF SMILES Flexibase

54420493

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,3S)-3-(2,2,2-trifluoroethoxy)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,3S)-3-(2,2,2-trif…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.50	2.33	-7.59	3	7	0	103	308.26	5	↓ MOL2 SDF SMILES Flexibase

54420496

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,3S)-3-(2,2,2-trifluoroethoxy)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,3S)-3-(2,2,2-trif…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.50	1.9	-8.03	3	7	0	103	308.26	5	↓ MOL2 SDF SMILES Flexibase

54420539

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,2S)-2-tert-butylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,2S)-2-tert-butylc…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.91	4.8	-4.49	3	6	0	94	266.345	3	↓ MOL2 SDF SMILES Flexibase

54420541

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,2R)-2-tert-butylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,2R)-2-tert-butylc…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.91	4.43	-4.46	3	6	0	94	266.345	3	↓ MOL2 SDF SMILES Flexibase

54420544

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,2S)-2-tert-butylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2S)-2-tert-butylc…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.91	4.43	-4.43	3	6	0	94	266.345	3	↓ MOL2 SDF SMILES Flexibase

54420546

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,2R)-2-tert-butylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2R)-2-tert-butylc…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.91	4.83	-4.48	3	6	0	94	266.345	3	↓ MOL2 SDF SMILES Flexibase

54421013

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,2R)-2-ethylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,2R)-2-ethylcycloh…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.08	3.36	-4.54	3	6	0	94	238.291	3	↓ MOL2 SDF SMILES Flexibase

54421016

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,2S)-2-ethylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,2S)-2-ethylcycloh…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.08	2.99	-4.63	3	6	0	94	238.291	3	↓ MOL2 SDF SMILES Flexibase

54421018

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,2R)-2-ethylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2R)-2-ethylcycloh…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.08	2.99	-4.63	3	6	0	94	238.291	3	↓ MOL2 SDF SMILES Flexibase

54421019

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,2S)-2-ethylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2S)-2-ethylcycloh…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.08	3.36	-4.54	3	6	0	94	238.291	3	↓ MOL2 SDF SMILES Flexibase

54421025

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,2R,5R)-2-isopropyl-5-methyl-cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2R,5R)-2-isopropy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.09	4.66	-4.61	3	6	0	94	266.345	3	↓ MOL2 SDF SMILES Flexibase

54421026

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,2R,5S)-2-isopropyl-5-methyl-cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2R,5S)-2-isopropy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.09	4.43	-4.52	3	6	0	94	266.345	3	↓ MOL2 SDF SMILES Flexibase

54421030

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2S,5R)-2-isopropy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.09	3.94	-4.62	3	6	0	94	266.345	3	↓ MOL2 SDF SMILES Flexibase

54421032

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,2S,5S)-2-isopropyl-5-methyl-cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2S,5S)-2-isopropy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.09	3.72	-4.57	3	6	0	94	266.345	3	↓ MOL2 SDF SMILES Flexibase

54421394

Analogs

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Popular Name: 4-amino-N-[(1R,3S)-3-(trifluoromethyl)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,3S)-3-(trifluorom…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.90	2.4	-6.38	3	6	0	94	278.234	3	↓ MOL2 SDF SMILES Flexibase

54421397

Analogs

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Popular Name: 4-amino-N-[(1R,3R)-3-(trifluoromethyl)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,3R)-3-(trifluorom…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.90	2.81	-6.33	3	6	0	94	278.234	3	↓ MOL2 SDF SMILES Flexibase

54421400

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,3S)-3-(trifluoromethyl)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,3S)-3-(trifluorom…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.90	2.81	-6.34	3	6	0	94	278.234	3	↓ MOL2 SDF SMILES Flexibase

54421403

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,3R)-3-(trifluoromethyl)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,3R)-3-(trifluorom…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.90	2.4	-6.38	3	6	0	94	278.234	3	↓ MOL2 SDF SMILES Flexibase

54430669

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1S,2R)-2-(trifluoromethyl)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,2R)-2-(trifluorom…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.13	3.36	-6.63	3	6	0	94	278.234	3	↓ MOL2 SDF SMILES Flexibase

54430670

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-amino-N-[(1R,2R)-2-(trifluoromethyl)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2R)-2-(trifluorom…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.13	2.92	-6.53	3	6	0	94	278.234	3	↓ MOL2 SDF SMILES Flexibase

54430671

Analogs

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Popular Name: 4-amino-N-[(1S,2S)-2-(trifluoromethyl)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1S,2S)-2-(trifluorom…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.13	2.92	-6.54	3	6	0	94	278.234	3	↓ MOL2 SDF SMILES Flexibase

54430672

Analogs

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Popular Name: 4-amino-N-[(1R,2S)-2-(trifluoromethyl)cyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-[(1R,2S)-2-(trifluorom…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.13	3.36	-6.67	3	6	0	94	278.234	3	↓ MOL2 SDF SMILES Flexibase

54430883

Analogs

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Popular Name: ethyl ethyl

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.97	3.44	-10.12	3	8	0	120	282.3	5	↓ MOL2 SDF SMILES Flexibase

54431090

Analogs

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Popular Name: 4-amino-N-methyl-N-(4-methylcyclohexyl)-1,2,5-oxadiazole-3-carboxamide 4-amino-N-methyl-N-(4-methylcycl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.36	4.16	-4.9	2	6	0	85	238.291	2	↓ MOL2 SDF SMILES Flexibase

54431116

Analogs

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Popular Name: 4-amino-N-methyl-N-[(1S,2R)-2-methylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-methyl-N-[(1S,2R)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.83	4.16	-4.86	2	6	0	85	238.291	2	↓ MOL2 SDF SMILES Flexibase

54431118

Analogs

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Popular Name: 4-amino-N-methyl-N-[(1S,2S)-2-methylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-methyl-N-[(1S,2S)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.83	4.6	-4.92	2	6	0	85	238.291	2	↓ MOL2 SDF SMILES Flexibase

54431121

Analogs

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Popular Name: 4-amino-N-methyl-N-[(1R,2R)-2-methylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-methyl-N-[(1R,2R)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.83	4.6	-4.91	2	6	0	85	238.291	2	↓ MOL2 SDF SMILES Flexibase

54431123

Analogs

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Popular Name: 4-amino-N-methyl-N-[(1R,2S)-2-methylcyclohexyl]-1,2,5-oxadiazole-3-carboxamide 4-amino-N-methyl-N-[(1R,2S)-2-me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.83	4.15	-4.9	2	6	0	85	238.291	2	↓ MOL2 SDF SMILES Flexibase

54431187

Analogs

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Popular Name: 4-amino-N-cyclohexyl-N-(2-hydroxyethyl)-1,2,5-oxadiazole-3-carboxamide 4-amino-N-cyclohexyl-N-(2-hydrox…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.95	1.85	-7.63	3	7	0	105	254.29	4	↓ MOL2 SDF SMILES Flexibase

54431707

Analogs

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Popular Name: 4-amino-N-(4-ethylcyclohexyl)-N-methyl-1,2,5-oxadiazole-3-carboxamide 4-amino-N-(4-ethylcyclohexyl)-N-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.04	4.82	-5.13	2	6	0	85	252.318	3	↓ MOL2 SDF SMILES Flexibase

54431887

Analogs

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Popular Name: 1-[(4-amino-1,2,5-oxadiazole-3-carbonyl)amino]cyclohexanecarboxylic 1-[(4-amino-1,2,5-oxadiazole-3-c…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-1.32	3.02	-46.1	3	8	-1	134	253.238	3	↓ MOL2 SDF SMILES Flexibase

54431914

Analogs

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Popular Name: 1-[(4-amino-1,2,5-oxadiazole-3-carbonyl)amino]-4-ethyl-cyclohexanecarboxylic 1-[(4-amino-1,2,5-oxadiazole-3-c…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.87	3.55	-43.91	3	8	-1	134	281.292	4	↓ MOL2 SDF SMILES Flexibase

54431915

Analogs

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Popular Name: 1-[(4-amino-1,2,5-oxadiazole-3-carbonyl)amino]-4-methyl-cyclohexanecarboxylic 1-[(4-amino-1,2,5-oxadiazole-3-c…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-1.55	3.61	-45.87	3	8	-1	134	267.265	3	↓ MOL2 SDF SMILES Flexibase

54431955

Analogs

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Popular Name: 4-[(4-amino-1,2,5-oxadiazole-3-carbonyl)amino]cyclohexanecarboxylic 4-[(4-amino-1,2,5-oxadiazole-3-c…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.02	1.99	-46.29	3	8	-1	134	253.238	3	↓ MOL2 SDF SMILES Flexibase

54432290

Analogs

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Popular Name: (1R,3R)-1-[(4-amino-1,2,5-oxadiazole-3-carbonyl)amino]-3-methyl-cyclohexanecarboxylic (1R,3R)-1-[(4-amino-1,2,5-oxadia…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-1.32	3.62	-46.09	3	8	-1	134	267.265	3	↓ MOL2 SDF SMILES Flexibase

54432292

Analogs

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Popular Name: (1R,3S)-1-[(4-amino-1,2,5-oxadiazole-3-carbonyl)amino]-3-methyl-cyclohexanecarboxylic (1R,3S)-1-[(4-amino-1,2,5-oxadia…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-1.32	3.81	-46.4	3	8	-1	134	267.265	3	↓ MOL2 SDF SMILES Flexibase

54432294

Analogs

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Popular Name: (1S,3R)-1-[(4-amino-1,2,5-oxadiazole-3-carbonyl)amino]-3-methyl-cyclohexanecarboxylic (1S,3R)-1-[(4-amino-1,2,5-oxadia…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-1.32	3.81	-46.43	3	8	-1	134	267.265	3	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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