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Analogs

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Popular Name: 8-(3-chlorophenyl)-2-(2-furylmethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-(3-chlorophenyl)-2-(2-furylmet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.72 10.74 -18.85 0 6 0 70 403.825 3 ↓

Analogs

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Popular Name: 8-(3-methoxypropyl)-2-(1H-1,2,4-triazol-5-yl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-(3-methoxypropyl)-2-(1H-1,2,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.45 8.54 -24.68 1 9 0 108 352.354 5 ↓

Analogs

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Popular Name: 2-(3-methoxypropyl)-8-(3-methyl-1H-1,2,4-triazol-5-yl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 2-(3-methoxypropyl)-8-(3-methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.54 8.4 -24.98 1 9 0 108 366.381 5 ↓
Hi High (pH 8-9.5) 0.54 8.24 -59.61 0 9 -1 106 365.373 5 ↓
Hi High (pH 8-9.5) 0.54 8.32 -25.22 1 9 0 108 366.381 5 ↓

Analogs

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Popular Name: 2-benzyl-8-(3-methyl-1H-1,2,4-triazol-5-yl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 2-benzyl-8-(3-methyl-1H-1,2,4-tr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.88 11.56 -24.68 1 8 0 98 384.399 3 ↓
Hi High (pH 8-9.5) 1.88 11.4 -59.63 0 8 -1 97 383.391 3 ↓

Analogs

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Popular Name: 8-[(4-methoxyphenyl)methyl]-2-(2-pyridyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-[(4-methoxyphenyl)methyl]-2-(2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.17 10.86 -29.5 0 7 0 79 410.433 4 ↓
Lo Low (pH 4.5-6) -4.40 10.19 -48.46 1 7 1 88 411.441 3 ↓

Analogs

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Popular Name: 8-[(4-methoxyphenyl)methyl]-2-(4-pyridyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-[(4-methoxyphenyl)methyl]-2-(4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.78 9.6 -22.86 0 7 0 79 410.433 4 ↓
Lo Low (pH 4.5-6) -0.95 9.73 -52.7 1 7 1 83 411.441 3 ↓

Analogs

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Popular Name: 8-[(4-methoxyphenyl)methyl]-2-(1H-1,2,4-triazol-5-yl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-[(4-methoxyphenyl)methyl]-2-(1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.85 11 -26.72 1 9 0 108 400.398 4 ↓

Analogs

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Popular Name: 2-[(4-methoxyphenyl)methyl]-8-(3-methyl-1H-1,2,4-triazol-5-yl)pyrido[4,3-b][1,6]naphthyridine-1,9-di 2-[(4-methoxyphenyl)methyl]-8-(3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.94 10.86 -25.83 1 9 0 108 414.425 4 ↓
Hi High (pH 8-9.5) 1.94 10.7 -60.6 0 9 -1 106 413.417 4 ↓

Analogs

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Popular Name: 8-(2-methoxyethyl)-2-[(4-methoxyphenyl)methyl]pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-(2-methoxyethyl)-2-[(4-methoxy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.04 8.01 -20.64 0 7 0 75 391.427 6 ↓

Analogs

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Popular Name: 8-[(4-methoxyphenyl)methyl]-2-(2-morpholinoethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-[(4-methoxyphenyl)methyl]-2-(2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.93 7.41 -24.73 0 8 0 79 446.507 6 ↓
Mid Mid (pH 6-8) 1.93 9.68 -59.76 1 8 1 80 447.515 6 ↓

Analogs

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Popular Name: 8-(2-furylmethyl)-2-(4-pyridyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-(2-furylmethyl)-2-(4-pyridyl)p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.98 8.44 -23.26 0 7 0 83 370.368 3 ↓
Lo Low (pH 4.5-6) -1.75 8.58 -53.38 1 7 1 87 371.376 2 ↓

Analogs

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Popular Name: 2-(2-furylmethyl)-8-(3-methyl-1H-1,2,4-triazol-5-yl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 2-(2-furylmethyl)-8-(3-methyl-1H…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.14 9.71 -23.45 1 9 0 112 374.36 3 ↓
Hi High (pH 8-9.5) 1.14 9.55 -57.55 0 9 -1 110 373.352 3 ↓

Analogs

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Popular Name: 8-(2-furylmethyl)-2-(2-hydroxyethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-(2-furylmethyl)-2-(2-hydroxyet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.62 5.08 -28.28 1 7 0 90 337.335 4 ↓

Analogs

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Popular Name: 2-(2-furylmethyl)-8-(3-methoxypropyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 2-(2-furylmethyl)-8-(3-methoxypr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 7.59 -21.96 0 7 0 79 365.389 6 ↓

Analogs

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Popular Name: 8-phenyl-2-(2-pyridylmethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-phenyl-2-(2-pyridylmethyl)pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.42 10.24 -17.08 0 6 0 70 380.407 3 ↓
Lo Low (pH 4.5-6) 2.42 10.73 -46.28 1 6 1 71 381.415 3 ↓

Analogs

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Popular Name: 8-(2-chlorophenyl)-2-(2-pyridylmethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-(2-chlorophenyl)-2-(2-pyridylm…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.26 11 -17.75 0 6 0 70 414.852 3 ↓
Lo Low (pH 4.5-6) 3.26 11.49 -46.86 1 6 1 71 415.86 3 ↓

Analogs

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Popular Name: 2-(3-chlorophenyl)-8-(2-pyridylmethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 2-(3-chlorophenyl)-8-(2-pyridylm…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.29 10.76 -25.14 0 6 0 70 414.852 3 ↓
Lo Low (pH 4.5-6) 3.29 11.17 -51.8 1 6 1 71 415.86 3 ↓

Analogs

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Popular Name: 2-(2-pyridyl)-8-(2-pyridylmethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 2-(2-pyridyl)-8-(2-pyridylmethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.95 9.75 -32.61 0 7 0 83 381.395 3 ↓
Lo Low (pH 4.5-6) 1.95 10.15 -57.53 1 7 1 84 382.403 3 ↓

Analogs

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Popular Name: 2-(4-pyridyl)-8-(2-pyridylmethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 2-(4-pyridyl)-8-(2-pyridylmethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.56 8.5 -25.8 0 7 0 83 381.395 3 ↓
Lo Low (pH 4.5-6) 1.56 8.9 -52.74 1 7 1 84 382.403 3 ↓

Analogs

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Popular Name: 8-(3-methyl-1H-1,2,4-triazol-5-yl)-2-(2-pyridylmethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-(3-methyl-1H-1,2,4-triazol-5-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.71 9.76 -21.28 1 9 0 111 385.387 3 ↓
Hi High (pH 8-9.5) 0.71 9.59 -54.9 0 9 -1 110 384.379 3 ↓
Lo Low (pH 4.5-6) 0.71 10.49 -57.24 2 9 1 113 386.395 3 ↓

Analogs

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Popular Name: 2-(2-hydroxyethyl)-8-(2-pyridylmethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 2-(2-hydroxyethyl)-8-(2-pyridylm…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.19 5.13 -31.06 1 7 0 90 348.362 4 ↓
Lo Low (pH 4.5-6) 0.19 5.53 -55.71 2 7 1 91 349.37 4 ↓

Analogs

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Popular Name: 8-(3-methoxypropyl)-2-(2-pyridylmethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-(3-methoxypropyl)-2-(2-pyridyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.08 7.64 -19.88 0 7 0 79 376.416 6 ↓
Lo Low (pH 4.5-6) 1.08 8.13 -47.81 1 7 1 80 377.424 6 ↓

Analogs

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Popular Name: 8-(2-methoxyethyl)-2-(2-pyridylmethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 8-(2-methoxyethyl)-2-(2-pyridylm…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.81 6.9 -16.38 0 7 0 79 362.389 5 ↓
Lo Low (pH 4.5-6) 0.81 7.39 -45.11 1 7 1 80 363.397 5 ↓

Analogs

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Popular Name: 2-(2-morpholinoethyl)-8-(2-pyridylmethyl)pyrido[4,3-b][1,6]naphthyridine-1,9-dione 2-(2-morpholinoethyl)-8-(2-pyrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.70 6.31 -27.79 0 8 0 82 417.469 5 ↓
Mid Mid (pH 6-8) 0.70 8.57 -62.63 1 8 1 83 418.477 5 ↓
Lo Low (pH 4.5-6) 0.70 8.97 -96.86 2 8 2 85 419.485 5 ↓

Analogs

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Popular Name: N-[4-[1,9-dioxo-2-(2-pyridylmethyl)pyrido[4,3-b][1,6]naphthyridin-8-yl]phenyl]acetamide N-[4-[1,9-dioxo-2-(2-pyridylmeth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.64 9.15 -22.57 1 8 0 99 437.459 4 ↓
Lo Low (pH 4.5-6) 1.64 9.63 -51.83 2 8 1 100 438.467 4 ↓

Parameters Provided:

ring.id = 12268
filter.purchasability = annotated
page.format = targets
page.num = 1

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 12268 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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