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Analogs

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Popular Name: 1,3,6-trimethyl-5-(phenethylamino)pyrido[3,2-e]pyrimidine-2,4-dione 1,3,6-trimethyl-5-(phenethylamin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.88 8.62 -9.4 1 6 0 69 324.384 4 ↓

Analogs

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Popular Name: 5-[2-(2-methoxyphenyl)ethylamino]-1,3,6-trimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 5-[2-(2-methoxyphenyl)ethylamino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.89 7.75 -9.28 1 7 0 78 354.41 5 ↓

Analogs

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Popular Name: 5-[2-(3,4-dimethoxyphenyl)ethylamino]-1,3,6-trimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 5-[2-(3,4-dimethoxyphenyl)ethyla…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.53 7.85 -13.77 1 8 0 87 384.436 6 ↓

Analogs

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Popular Name: 5-[2-(4-methoxyphenyl)ethylamino]-1,3,6-trimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 5-[2-(4-methoxyphenyl)ethylamino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.94 7.93 -11.13 1 7 0 78 354.41 5 ↓

Analogs

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Popular Name: 5-[2-(3-methoxyphenyl)ethylamino]-1,3,6-trimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 5-[2-(3-methoxyphenyl)ethylamino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.92 7.93 -11.94 1 7 0 78 354.41 5 ↓

Analogs

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Popular Name: 4-[2-[(1,3,6-trimethyl-2,4-dioxo-pyrido[3,2-e]pyrimidin-5-yl)amino]ethyl]benzenesulfonamide 4-[2-[(1,3,6-trimethyl-2,4-dioxo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.58 3.47 -19.64 3 9 0 129 403.464 5 ↓

Analogs

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Popular Name: 6-ethyl-5-[2-(2-methoxyphenyl)ethylamino]-1,3-dimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 6-ethyl-5-[2-(2-methoxyphenyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.36 8.73 -9.59 1 7 0 78 368.437 6 ↓

Analogs

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Popular Name: 5-[2-(3,4-dimethoxyphenyl)ethylamino]-6-ethyl-1,3-dimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 5-[2-(3,4-dimethoxyphenyl)ethyla…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.00 8.6 -13.2 1 8 0 87 398.463 7 ↓

Analogs

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Popular Name: 6-ethyl-5-[2-(4-methoxyphenyl)ethylamino]-1,3-dimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 6-ethyl-5-[2-(4-methoxyphenyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.41 8.68 -10.54 1 7 0 78 368.437 6 ↓

Analogs

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Popular Name: 6-ethyl-5-[2-(3-methoxyphenyl)ethylamino]-1,3-dimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 6-ethyl-5-[2-(3-methoxyphenyl)et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.38 8.68 -11.33 1 7 0 78 368.437 6 ↓

Analogs

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Popular Name: 4-[2-[(6-ethyl-1,3-dimethyl-2,4-dioxo-pyrido[3,2-e]pyrimidin-5-yl)amino]ethyl]benzenesulfonamide 4-[2-[(6-ethyl-1,3-dimethyl-2,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.04 4.25 -19.2 3 9 0 129 417.491 6 ↓

Analogs

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Popular Name: 1,3-dimethyl-5-(phenethylamino)pyrido[3,2-e]pyrimidine-2,4-dione 1,3-dimethyl-5-(phenethylamino)p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.45 7.98 -7.82 1 6 0 69 310.357 4 ↓
Lo Low (pH 4.5-6) -2.28 8.27 -41.12 2 6 1 71 311.365 4 ↓

Analogs

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Popular Name: 5-[2-(2-methoxyphenyl)ethylamino]-1,3-dimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 5-[2-(2-methoxyphenyl)ethylamino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.46 7.37 -8.89 1 7 0 78 340.383 5 ↓
Lo Low (pH 4.5-6) -2.27 7.66 -41 2 7 1 80 341.391 5 ↓

Analogs

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Popular Name: 5-[2-(3,4-dimethoxyphenyl)ethylamino]-1,3-dimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 5-[2-(3,4-dimethoxyphenyl)ethyla…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.10 7.22 -12.06 1 8 0 87 370.409 6 ↓
Lo Low (pH 4.5-6) -2.64 7.5 -46.43 2 8 1 89 371.417 6 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[2-(4-methoxyphenyl)ethylamino]-1,3-dimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 5-[2-(4-methoxyphenyl)ethylamino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 7.3 -9.5 1 7 0 78 340.383 5 ↓
Lo Low (pH 4.5-6) -2.23 7.59 -43.17 2 7 1 80 341.391 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5-[2-(3-methoxyphenyl)ethylamino]-1,3-dimethyl-pyrido[3,2-e]pyrimidine-2,4-dione 5-[2-(3-methoxyphenyl)ethylamino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.49 7.3 -9.4 1 7 0 78 340.383 5 ↓
Lo Low (pH 4.5-6) -2.25 7.59 -42.46 2 7 1 80 341.391 5 ↓

Analogs

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Popular Name: 4-[2-[(1,3-dimethyl-2,4-dioxo-pyrido[3,2-e]pyrimidin-5-yl)amino]ethyl]benzenesulfonamide 4-[2-[(1,3-dimethyl-2,4-dioxo-py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.15 2.84 -17.73 3 9 0 129 389.437 5 ↓
Lo Low (pH 4.5-6) -3.59 3.13 -51.82 4 9 1 131 390.445 5 ↓

Parameters Provided:

ring.id = 125623
filter.purchasability = annotated
page.format = targets
page.num = 1

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SQL Query Was

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