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ZINC Item

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36969273

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 1-[(1-methylsulfonylpiperidine-4-carbonyl)amino]cyclopentanecarboxylic 1-[(1-methylsulfonylpiperidine-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-1.67	3.52	-68.15	1	7	-1	107	317.387	4	↓ MOL2 SDF SMILES Flexibase

37092844

Analogs

37824811
45487350
6726634
16625181

Draw Identity 99% 90% 80% 70%

Popular Name: N-cyclopentyl-N-methyl-piperidine-4-carboxamide N-cyclopentyl-N-methyl-piperidin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.27	5.09	-46.63	2	3	1	37	211.329	2	↓ MOL2 SDF SMILES Flexibase

62839442

Analogs

15416807

Draw Identity 99% 90% 80% 70%

Popular Name: MFCD21605966 MFCD21605966

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.60	4.05	-39.38	3	3	1	46	211.329	2	↓ MOL2 SDF SMILES Flexibase

62839756

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-cyclopentyl-N,4-dimethyl-piperidine-4-carboxamide N-cyclopentyl-N,4-dimethyl-piper…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.51	5.1	-40.39	2	3	1	37	225.356	2	↓ MOL2 SDF SMILES Flexibase

62839839

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-cyclopentyl-N-ethyl-4-methyl-piperidine-4-carboxamide N-cyclopentyl-N-ethyl-4-methyl-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.89	5.81	-40.63	2	3	1	37	239.383	3	↓ MOL2 SDF SMILES Flexibase

62840686

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-amino-2-oxo-ethyl)-N-cyclopentyl-4-methyl-piperidine-4-carboxamide N-(2-amino-2-oxo-ethyl)-N-cyclop…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.25	2.22	-47.16	4	5	1	80	268.381	4	↓ MOL2 SDF SMILES Flexibase

62840738

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-allyl-N-cyclopentyl-4-methyl-piperidine-4-carboxamide N-allyl-N-cyclopentyl-4-methyl-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.16	6.45	-40.11	2	3	1	37	251.394	4	↓ MOL2 SDF SMILES Flexibase

62840820

Analogs

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Popular Name: N-cyclopentyl-N-(2-hydroxyethyl)-4-methyl-piperidine-4-carboxamide N-cyclopentyl-N-(2-hydroxyethyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.88	3.75	-40.37	3	4	1	57	255.382	4	↓ MOL2 SDF SMILES Flexibase

62840822

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-cyclopentyl-N-(2-dimethylaminoethyl)-4-methyl-piperidine-4-carboxamide N-cyclopentyl-N-(2-dimethylamino…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.54	7.2	-83.6	3	4	2	41	283.46	5	↓ MOL2 SDF SMILES Flexibase

62841003

Analogs

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Popular Name: 1-[(4-methylpiperidine-4-carbonyl)amino]cyclopentanecarboxylic 1-[(4-methylpiperidine-4-carbony…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-1.06	5	-77.31	3	5	0	86	254.33	3	↓ MOL2 SDF SMILES Flexibase

62841042

Analogs

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Popular Name: 2-[cyclopentyl-(4-methylpiperidine-4-carbonyl)amino]acetic 2-[cyclopentyl-(4-methylpiperidi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.15	6.13	-77.55	2	5	0	77	268.357	4	↓ MOL2 SDF SMILES Flexibase

62841239

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-methyl-N-(1-methylcyclopentyl)piperidine-4-carboxamide 4-methyl-N-(1-methylcyclopentyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.05	4.43	-38.8	3	3	1	46	225.356	2	↓ MOL2 SDF SMILES Flexibase

62841430

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,2S)-2-methoxycyclopentyl]-4-methyl-piperidine-4-carboxamide N-[(1R,2S)-2-methoxycyclopentyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.07	3.51	-38.18	3	4	1	55	241.355	3	↓ MOL2 SDF SMILES Flexibase

62841431

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2S)-2-methoxycyclopentyl]-4-methyl-piperidine-4-carboxamide N-[(1S,2S)-2-methoxycyclopentyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.07	3.06	-41.02	3	4	1	55	241.355	3	↓ MOL2 SDF SMILES Flexibase

62841432

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,2R)-2-methoxycyclopentyl]-4-methyl-piperidine-4-carboxamide N-[(1R,2R)-2-methoxycyclopentyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.07	3.06	-42.31	3	4	1	55	241.355	3	↓ MOL2 SDF SMILES Flexibase

62841433

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2R)-2-methoxycyclopentyl]-4-methyl-piperidine-4-carboxamide N-[(1S,2R)-2-methoxycyclopentyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.07	3.46	-38.73	3	4	1	55	241.355	3	↓ MOL2 SDF SMILES Flexibase

62841501

Analogs

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Popular Name: N-[1-(hydroxymethyl)cyclopentyl]-4-methyl-piperidine-4-carboxamide N-[1-(hydroxymethyl)cyclopentyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.04	1.18	-38.02	4	4	1	66	241.355	3	↓ MOL2 SDF SMILES Flexibase

62841571

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,2S)-2-cyanocyclopentyl]-4-methyl-piperidine-4-carboxamide N-[(1R,2S)-2-cyanocyclopentyl]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.25	4.45	-39.07	3	4	1	69	236.339	2	↓ MOL2 SDF SMILES Flexibase

62841572

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2S)-2-cyanocyclopentyl]-4-methyl-piperidine-4-carboxamide N-[(1S,2S)-2-cyanocyclopentyl]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.25	4.27	-45.29	3	4	1	69	236.339	2	↓ MOL2 SDF SMILES Flexibase

62841573

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,2R)-2-cyanocyclopentyl]-4-methyl-piperidine-4-carboxamide N-[(1R,2R)-2-cyanocyclopentyl]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.25	4.27	-49	3	4	1	69	236.339	2	↓ MOL2 SDF SMILES Flexibase

62841574

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2R)-2-cyanocyclopentyl]-4-methyl-piperidine-4-carboxamide N-[(1S,2R)-2-cyanocyclopentyl]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.25	4.45	-39.31	3	4	1	69	236.339	2	↓ MOL2 SDF SMILES Flexibase

62847511

Analogs

15416807

Draw Identity 99% 90% 80% 70%

Popular Name: N-cyclopentyl-4-ethyl-piperidine-4-carboxamide N-cyclopentyl-4-ethyl-piperidine…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.93	4.51	-40.99	3	3	1	46	225.356	3	↓ MOL2 SDF SMILES Flexibase

62847512

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-cyclopentyl-4-propyl-piperidine-4-carboxamide N-cyclopentyl-4-propyl-piperidin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.49	5.28	-41.22	3	3	1	46	239.383	4	↓ MOL2 SDF SMILES Flexibase

62848053

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-cyclopentyl-4-ethyl-N-methyl-piperidine-4-carboxamide N-cyclopentyl-4-ethyl-N-methyl-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.85	5.86	-39.54	2	3	1	37	239.383	3	↓ MOL2 SDF SMILES Flexibase

62848217

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-cyclopentyl-N,4-diethyl-piperidine-4-carboxamide N-cyclopentyl-N,4-diethyl-piperi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.23	6.12	-40.12	2	3	1	37	253.41	4	↓ MOL2 SDF SMILES Flexibase

62848218

Analogs

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Popular Name: N-cyclopentyl-N-ethyl-4-propyl-piperidine-4-carboxamide N-cyclopentyl-N-ethyl-4-propyl-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.79	6.73	-40.06	2	3	1	37	267.437	5	↓ MOL2 SDF SMILES Flexibase

62849113

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-(2-amino-2-oxo-ethyl)-N-cyclopentyl-4-ethyl-piperidine-4-carboxamide N-(2-amino-2-oxo-ethyl)-N-cyclop…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.58	2.61	-50.11	4	5	1	80	282.408	5	↓ MOL2 SDF SMILES Flexibase

62849114

Analogs

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Popular Name: N-(2-amino-2-oxo-ethyl)-N-cyclopentyl-4-propyl-piperidine-4-carboxamide N-(2-amino-2-oxo-ethyl)-N-cyclop…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.14	3.29	-49.65	4	5	1	80	296.435	6	↓ MOL2 SDF SMILES Flexibase

62849161

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-allyl-N-cyclopentyl-4-ethyl-piperidine-4-carboxamide N-allyl-N-cyclopentyl-4-ethyl-pi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.49	6.79	-40.27	2	3	1	37	265.421	5	↓ MOL2 SDF SMILES Flexibase

62849162

Analogs

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Popular Name: N-allyl-N-cyclopentyl-4-propyl-piperidine-4-carboxamide N-allyl-N-cyclopentyl-4-propyl-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.05	7.4	-40.44	2	3	1	37	279.448	6	↓ MOL2 SDF SMILES Flexibase

62849265

Analogs

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Popular Name: N-cyclopentyl-N-(2-hydroxyethyl)-4-propyl-piperidine-4-carboxamide N-cyclopentyl-N-(2-hydroxyethyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.78	4.31	-39.23	3	4	1	57	283.436	6	↓ MOL2 SDF SMILES Flexibase

62849267

Analogs

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Popular Name: N-cyclopentyl-N-(2-dimethylaminoethyl)-4-ethyl-piperidine-4-carboxamide N-cyclopentyl-N-(2-dimethylamino…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.88	7.6	-89.3	3	4	2	41	297.487	6	↓ MOL2 SDF SMILES Flexibase

62849539

Analogs

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Popular Name: 1-[(4-ethylpiperidine-4-carbonyl)amino]cyclopentanecarboxylic 1-[(4-ethylpiperidine-4-carbonyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.73	5.45	-64.48	3	5	0	86	268.357	4	↓ MOL2 SDF SMILES Flexibase

62849540

Analogs

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Popular Name: 1-[(4-propylpiperidine-4-carbonyl)amino]cyclopentanecarboxylic 1-[(4-propylpiperidine-4-carbony…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-0.17	6.29	-80.55	3	5	0	86	282.384	5	↓ MOL2 SDF SMILES Flexibase

62849597

Analogs

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Popular Name: 2-[cyclopentyl-(4-ethylpiperidine-4-carbonyl)amino]acetic 2-[cyclopentyl-(4-ethylpiperidin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.18	6.44	-63.53	2	5	0	77	282.384	5	↓ MOL2 SDF SMILES Flexibase

62849598

Analogs

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Popular Name: 2-[cyclopentyl-(4-propylpiperidine-4-carbonyl)amino]acetic 2-[cyclopentyl-(4-propylpiperidi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.74	7.08	-61.68	2	5	0	77	296.411	6	↓ MOL2 SDF SMILES Flexibase

62849853

Analogs

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Popular Name: 4-ethyl-N-(1-methylcyclopentyl)piperidine-4-carboxamide 4-ethyl-N-(1-methylcyclopentyl)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.38	4.85	-40.34	3	3	1	46	239.383	3	↓ MOL2 SDF SMILES Flexibase

62849854

Analogs

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Popular Name: N-(1-methylcyclopentyl)-4-propyl-piperidine-4-carboxamide N-(1-methylcyclopentyl)-4-propyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.94	5.66	-40.48	3	3	1	46	253.41	4	↓ MOL2 SDF SMILES Flexibase

62850212

Analogs

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Popular Name: 4-ethyl-N-[(1R,2S)-2-methoxycyclopentyl]piperidine-4-carboxamide 4-ethyl-N-[(1R,2S)-2-methoxycycl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.40	3.97	-39.68	3	4	1	55	255.382	4	↓ MOL2 SDF SMILES Flexibase

62850213

Analogs

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Popular Name: 4-ethyl-N-[(1S,2S)-2-methoxycyclopentyl]piperidine-4-carboxamide 4-ethyl-N-[(1S,2S)-2-methoxycycl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.40	3.52	-42.44	3	4	1	55	255.382	4	↓ MOL2 SDF SMILES Flexibase

62850214

Analogs

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Popular Name: 4-ethyl-N-[(1R,2R)-2-methoxycyclopentyl]piperidine-4-carboxamide 4-ethyl-N-[(1R,2R)-2-methoxycycl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.40	3.53	-44.12	3	4	1	55	255.382	4	↓ MOL2 SDF SMILES Flexibase

62850215

Analogs

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Popular Name: 4-ethyl-N-[(1S,2R)-2-methoxycyclopentyl]piperidine-4-carboxamide 4-ethyl-N-[(1S,2R)-2-methoxycycl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.40	3.94	-38.7	3	4	1	55	255.382	4	↓ MOL2 SDF SMILES Flexibase

62850216

Analogs

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Popular Name: N-[(1R,2S)-2-methoxycyclopentyl]-4-propyl-piperidine-4-carboxamide N-[(1R,2S)-2-methoxycyclopentyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	4.74	-39.86	3	4	1	55	269.409	5	↓ MOL2 SDF SMILES Flexibase

62850217

Analogs

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Popular Name: N-[(1S,2S)-2-methoxycyclopentyl]-4-propyl-piperidine-4-carboxamide N-[(1S,2S)-2-methoxycyclopentyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	4.3	-42.67	3	4	1	55	269.409	5	↓ MOL2 SDF SMILES Flexibase

62850218

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,2R)-2-methoxycyclopentyl]-4-propyl-piperidine-4-carboxamide N-[(1R,2R)-2-methoxycyclopentyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	4.29	-44.36	3	4	1	55	269.409	5	↓ MOL2 SDF SMILES Flexibase

62850219

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2R)-2-methoxycyclopentyl]-4-propyl-piperidine-4-carboxamide N-[(1S,2R)-2-methoxycyclopentyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.96	4.7	-38.95	3	4	1	55	269.409	5	↓ MOL2 SDF SMILES Flexibase

62850327

Analogs

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Popular Name: 4-ethyl-N-[1-(hydroxymethyl)cyclopentyl]piperidine-4-carboxamide 4-ethyl-N-[1-(hydroxymethyl)cycl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.37	3.07	-40.78	4	4	1	66	255.382	4	↓ MOL2 SDF SMILES Flexibase

62850328

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[1-(hydroxymethyl)cyclopentyl]-4-propyl-piperidine-4-carboxamide N-[1-(hydroxymethyl)cyclopentyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.93	3.84	-40.58	4	4	1	66	269.409	5	↓ MOL2 SDF SMILES Flexibase

62850449

Analogs

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Popular Name: N-[(1R,2S)-2-cyanocyclopentyl]-4-ethyl-piperidine-4-carboxamide N-[(1R,2S)-2-cyanocyclopentyl]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.58	4.92	-41.86	3	4	1	69	250.366	3	↓ MOL2 SDF SMILES Flexibase

62850450

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2S)-2-cyanocyclopentyl]-4-ethyl-piperidine-4-carboxamide N-[(1S,2S)-2-cyanocyclopentyl]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.58	4.75	-46.49	3	4	1	69	250.366	3	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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filter.purchasability = annotated
page.format = targets
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Structural Results Found: (before additional filtering)

SQL Query Was

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