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Popular Name: 2-tert-butoxy-6-thiomorpholino-pyridin-3-amine 2-tert-butoxy-6-thiomorpholino-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.55 6.21 -4.87 2 4 0 51 267.398 3 ↓

Analogs

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Popular Name: 2-isobutoxy-6-thiomorpholino-pyridin-3-amine 2-isobutoxy-6-thiomorpholino-pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.48 5.23 -5.44 2 4 0 51 267.398 4 ↓

Analogs

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Popular Name: 2-propoxy-6-thiomorpholino-pyridin-3-amine 2-propoxy-6-thiomorpholino-pyrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.24 4.54 -5.67 2 4 0 51 253.371 4 ↓

Analogs

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Popular Name: 2-isopropoxy-6-thiomorpholino-pyridin-3-amine 2-isopropoxy-6-thiomorpholino-py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 4.66 -5.54 2 4 0 51 253.371 3 ↓

Analogs

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Popular Name: 2-ethoxy-6-thiomorpholino-pyridin-3-amine 2-ethoxy-6-thiomorpholino-pyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.74 3.74 -5.77 2 4 0 51 239.344 3 ↓

Analogs

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Popular Name: 2-methoxy-6-thiomorpholino-pyridin-3-amine 2-methoxy-6-thiomorpholino-pyrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 2.8 -5.93 2 4 0 51 225.317 2 ↓

Analogs

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Popular Name: [6-methyl-2-[(3S)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanamine [6-methyl-2-[(3S)-3-methylthiomo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.05 5.19 -104.11 4 3 2 45 239.388 2 ↓
Hi High (pH 8-9.5) 1.05 4.81 -26.79 3 3 1 43 238.38 2 ↓
Hi High (pH 8-9.5) 1.05 4.37 -4.8 2 3 0 42 237.372 2 ↓

Analogs

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Popular Name: [6-methyl-2-[(3R)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanamine [6-methyl-2-[(3R)-3-methylthiomo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.05 5.44 -102.55 4 3 2 45 239.388 2 ↓
Hi High (pH 8-9.5) 1.05 5.14 -26.64 3 3 1 43 238.38 2 ↓
Hi High (pH 8-9.5) 1.05 4.74 -4.76 2 3 0 42 237.372 2 ↓

Analogs

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Popular Name: [2-[(3R)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanamine [2-[(3R)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.99 4.37 -49.21 3 3 1 44 224.353 2 ↓
Hi High (pH 8-9.5) 0.99 4.05 -4.64 2 3 0 42 223.345 2 ↓
Mid Mid (pH 6-8) 0.99 4.83 -104.04 4 3 2 45 225.361 2 ↓

Analogs

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Popular Name: [2-[(3S)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanamine [2-[(3S)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.99 4.13 -50.15 3 3 1 44 224.353 2 ↓
Hi High (pH 8-9.5) 0.99 3.91 -4.58 2 3 0 42 223.345 2 ↓
Mid Mid (pH 6-8) 0.99 4.6 -105.56 4 3 2 45 225.361 2 ↓

Analogs

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Popular Name: [6-[(3R)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanamine [6-[(3R)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.05 3.97 -49.95 3 3 1 44 224.353 2 ↓
Hi High (pH 8-9.5) 1.05 3.56 -4.27 2 3 0 42 223.345 2 ↓
Mid Mid (pH 6-8) 1.05 4.42 -110.99 4 3 2 45 225.361 2 ↓

Analogs

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Popular Name: [6-[(3S)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanamine [6-[(3S)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.05 3.97 -50.14 3 3 1 44 224.353 2 ↓
Hi High (pH 8-9.5) 1.05 3.56 -4.21 2 3 0 42 223.345 2 ↓
Mid Mid (pH 6-8) 1.05 4.43 -111.26 4 3 2 45 225.361 2 ↓

Analogs

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Popular Name: [2-[(3R)-3-methylthiomorpholin-4-yl]-4-pyridyl]methanamine [2-[(3R)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.99 3.98 -51.66 3 3 1 44 224.353 2 ↓
Hi High (pH 8-9.5) 0.99 4.04 -31.04 3 3 1 43 224.353 2 ↓
Hi High (pH 8-9.5) 0.99 3.59 -4.66 2 3 0 42 223.345 2 ↓

Analogs

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Popular Name: [2-[(3S)-3-methylthiomorpholin-4-yl]-4-pyridyl]methanamine [2-[(3S)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.99 3.98 -52.2 3 3 1 44 224.353 2 ↓
Hi High (pH 8-9.5) 0.99 4.05 -31.02 3 3 1 43 224.353 2 ↓
Hi High (pH 8-9.5) 0.99 3.59 -4.66 2 3 0 42 223.345 2 ↓

Analogs

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Popular Name: 5-amino-2-[(3R)-3-methylthiomorpholin-4-yl]pyridine-3-carbonitrile 5-amino-2-[(3R)-3-methylthiomorp…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.19 4.49 -7.04 2 4 0 66 234.328 1 ↓

Analogs

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Popular Name: 5-amino-2-[(3S)-3-methylthiomorpholin-4-yl]pyridine-3-carbonitrile 5-amino-2-[(3S)-3-methylthiomorp…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.19 4.49 -7.06 2 4 0 66 234.328 1 ↓

Analogs

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Popular Name: 2-[(3R)-3-methylthiomorpholin-4-yl]pyridin-3-amine 2-[(3R)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.29 4.74 -28.92 3 3 1 43 210.326 1 ↓
Mid Mid (pH 6-8) 1.29 4.26 -4.95 2 3 0 42 209.318 1 ↓

Analogs

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Popular Name: 2-[(3S)-3-methylthiomorpholin-4-yl]pyridin-3-amine 2-[(3S)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.29 4.72 -29 3 3 1 43 210.326 1 ↓
Mid Mid (pH 6-8) 1.29 4.25 -4.95 2 3 0 42 209.318 1 ↓

Analogs

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Popular Name: 5-bromo-2-[(3R)-3-methylthiomorpholin-4-yl]pyridin-3-amine 5-bromo-2-[(3R)-3-methylthiomorp…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.25 4.85 -4.18 2 3 0 42 288.214 1 ↓

Analogs

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Popular Name: 5-bromo-2-[(3S)-3-methylthiomorpholin-4-yl]pyridin-3-amine 5-bromo-2-[(3S)-3-methylthiomorp…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.25 4.84 -4.23 2 3 0 42 288.214 1 ↓

Analogs

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Popular Name: 2-[(3R)-3-methylthiomorpholin-4-yl]pyridin-4-amine 2-[(3R)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.88 4.28 -29.33 3 3 1 43 210.326 1 ↓

Analogs

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Popular Name: 2-[(3S)-3-methylthiomorpholin-4-yl]pyridin-4-amine 2-[(3S)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.88 4.29 -29.32 3 3 1 43 210.326 1 ↓

Analogs

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Popular Name: 6-[(3R)-3-methylthiomorpholin-4-yl]pyridin-3-amine 6-[(3R)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 4.3 -29.28 3 3 1 43 210.326 1 ↓
Mid Mid (pH 6-8) 1.51 3.85 -4.93 2 3 0 42 209.318 1 ↓

Analogs

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Popular Name: 6-[(3S)-3-methylthiomorpholin-4-yl]pyridin-3-amine 6-[(3S)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 4.25 -28.82 3 3 1 43 210.326 1 ↓
Mid Mid (pH 6-8) 1.51 3.85 -4.96 2 3 0 42 209.318 1 ↓

Analogs

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Popular Name: 5-methyl-6-[(3S)-3-methylthiomorpholin-4-yl]pyridin-3-amine 5-methyl-6-[(3S)-3-methylthiomor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.89 5.41 -27.84 3 3 1 43 224.353 1 ↓
Mid Mid (pH 6-8) 1.89 4.94 -5.2 2 3 0 42 223.345 1 ↓

Analogs

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Popular Name: 5-methyl-6-[(3R)-3-methylthiomorpholin-4-yl]pyridin-3-amine 5-methyl-6-[(3R)-3-methylthiomor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.89 5.22 -27.88 3 3 1 43 224.353 1 ↓
Mid Mid (pH 6-8) 1.89 4.75 -5.2 2 3 0 42 223.345 1 ↓

Analogs

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Popular Name: 2-methoxy-6-[(3R)-3-methylthiomorpholin-4-yl]pyridin-3-amine 2-methoxy-6-[(3R)-3-methylthiomo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.69 2.48 -5.09 2 4 0 51 239.344 2 ↓

Analogs

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Popular Name: 2-methoxy-6-[(3S)-3-methylthiomorpholin-4-yl]pyridin-3-amine 2-methoxy-6-[(3S)-3-methylthiomo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.69 2.49 -5.1 2 4 0 51 239.344 2 ↓

Analogs

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Popular Name: 2-[(3R)-3-methylthiomorpholin-4-yl]pyridine-4-carboxamidine 2-[(3R)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.20 4.31 -99.95 5 4 2 69 238.36 2 ↓
Hi High (pH 8-9.5) 0.20 3.84 -39.05 4 4 1 68 237.352 2 ↓

Analogs

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Popular Name: 2-[(3S)-3-methylthiomorpholin-4-yl]pyridine-4-carboxamidine 2-[(3S)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.20 4.33 -99.9 5 4 2 69 238.36 2 ↓
Hi High (pH 8-9.5) 0.20 3.85 -39.03 4 4 1 68 237.352 2 ↓

Analogs

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Popular Name: 6-[(3R)-3-methylthiomorpholin-4-yl]pyridine-3-carboxamidine 6-[(3R)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.25 3.8 -37.67 4 4 1 68 237.352 2 ↓

Analogs

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Popular Name: 6-[(3S)-3-methylthiomorpholin-4-yl]pyridine-3-carboxamidine 6-[(3S)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.25 3.82 -37.6 4 4 1 68 237.352 2 ↓

Analogs

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Popular Name: 2-[(3R)-3-methylthiomorpholin-4-yl]pyridine-3-carboxamidine 2-[(3R)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.20 3.62 -36.74 4 4 1 68 237.352 2 ↓
Hi High (pH 8-9.5) 0.20 4.85 -6.23 3 4 0 66 236.344 2 ↓

Analogs

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Popular Name: 2-[(3S)-3-methylthiomorpholin-4-yl]pyridine-3-carboxamidine 2-[(3S)-3-methylthiomorpholin-4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.20 3.63 -36.98 4 4 1 68 237.352 2 ↓
Hi High (pH 8-9.5) 0.20 4.73 -6.25 3 4 0 66 236.344 2 ↓

Analogs

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Popular Name: [2-[(3R)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanol [2-[(3R)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.15 4.12 -30.62 2 3 1 38 225.337 2 ↓
Mid Mid (pH 6-8) 1.15 3.64 -5.76 1 3 0 36 224.329 2 ↓

Analogs

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Popular Name: [2-[(3S)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanol [2-[(3S)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.15 4.2 -30.6 2 3 1 38 225.337 2 ↓
Mid Mid (pH 6-8) 1.15 3.73 -5.73 1 3 0 36 224.329 2 ↓

Analogs

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Popular Name: [5-chloro-6-[(3R)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanol [5-chloro-6-[(3R)-3-methylthiomo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.81 4.05 -5.79 1 3 0 36 258.774 2 ↓

Analogs

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Popular Name: [5-chloro-6-[(3S)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanol [5-chloro-6-[(3S)-3-methylthiomo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.81 4.05 -5.84 1 3 0 36 258.774 2 ↓

Analogs

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Popular Name: [3-chloro-6-[(3R)-3-methylthiomorpholin-4-yl]-2-pyridyl]methanol [3-chloro-6-[(3R)-3-methylthiomo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.28 3.63 -5.93 1 3 0 36 258.774 2 ↓

Analogs

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Popular Name: [3-chloro-6-[(3S)-3-methylthiomorpholin-4-yl]-2-pyridyl]methanol [3-chloro-6-[(3S)-3-methylthiomo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.28 3.63 -5.93 1 3 0 36 258.774 2 ↓

Analogs

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Popular Name: [5-bromo-2-[(3R)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanol [5-bromo-2-[(3R)-3-methylthiomor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 4.25 -5.11 1 3 0 36 303.225 2 ↓

Analogs

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Popular Name: [5-bromo-2-[(3S)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanol [5-bromo-2-[(3S)-3-methylthiomor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 4.33 -5.15 1 3 0 36 303.225 2 ↓

Analogs

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Popular Name: [2-[(3R)-3-methylthiomorpholin-4-yl]-4-pyridyl]methanol [2-[(3R)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.15 3.72 -32.08 2 3 1 38 225.337 2 ↓
Mid Mid (pH 6-8) 1.15 3.27 -6.3 1 3 0 36 224.329 2 ↓

Analogs

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Popular Name: [2-[(3S)-3-methylthiomorpholin-4-yl]-4-pyridyl]methanol [2-[(3S)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.15 3.73 -32.06 2 3 1 38 225.337 2 ↓
Mid Mid (pH 6-8) 1.15 3.27 -6.34 1 3 0 36 224.329 2 ↓

Analogs

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Popular Name: [6-[(3R)-3-methylthiomorpholin-4-yl]-2-pyridyl]methanol [6-[(3R)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.27 3.81 -28.78 2 3 1 38 225.337 2 ↓
Mid Mid (pH 6-8) 1.27 3.39 -5.35 1 3 0 36 224.329 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [6-[(3S)-3-methylthiomorpholin-4-yl]-2-pyridyl]methanol [6-[(3S)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.27 3.83 -28.78 2 3 1 38 225.337 2 ↓
Mid Mid (pH 6-8) 1.27 3.4 -5.33 1 3 0 36 224.329 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [6-[(3R)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanol [6-[(3R)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.20 3.71 -30.79 2 3 1 38 225.337 2 ↓
Mid Mid (pH 6-8) 1.20 3.26 -6.32 1 3 0 36 224.329 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [6-[(3S)-3-methylthiomorpholin-4-yl]-3-pyridyl]methanol [6-[(3S)-3-methylthiomorpholin-4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.20 3.72 -30.75 2 3 1 38 225.337 2 ↓
Mid Mid (pH 6-8) 1.20 3.26 -6.28 1 3 0 36 224.329 2 ↓

Analogs

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Popular Name: (3R)-4-[4-(chloromethyl)-2-pyridyl]-3-methyl-thiomorpholine (3R)-4-[4-(chloromethyl)-2-pyrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.38 7.24 -4.99 0 2 0 16 242.775 2 ↓
Mid Mid (pH 6-8) 2.38 7.69 -33.41 1 2 1 17 243.783 2 ↓

Analogs

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Popular Name: (3S)-4-[4-(chloromethyl)-2-pyridyl]-3-methyl-thiomorpholine (3S)-4-[4-(chloromethyl)-2-pyrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.38 7.24 -4.91 0 2 0 16 242.775 2 ↓
Mid Mid (pH 6-8) 2.38 7.7 -33.39 1 2 1 17 243.783 2 ↓

Parameters Provided:

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