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ZINC Item

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13282230

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 4-methoxy-7-(3-methylbut-2-enoxy)furo[2,3-b]quinoline 4-methoxy-7-(3-methylbut-2-enoxy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.58	5.64	-11.59	0	4	0	45	283.327	4	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.58	6.48	-24.45	1	4	1	46	284.335	4	↓ MOL2 SDF SMILES Flexibase

2090247

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: dimethoxy-[(2,2,5,5-tetramethyl-1,3-dioxolan-4-yl)methoxy]BLAH dimethoxy-[(2,2,5,5-tetramethyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.12	-0.71	-16.74	0	7	0	72	387.432	5	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.12	0	-28.22	1	7	1	73	388.44	5	↓ MOL2 SDF SMILES Flexibase

2090249

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: dimethoxy-[(2,2,5,5-tetramethyl-1,3-dioxolan-4-yl)methoxy]BLAH dimethoxy-[(2,2,5,5-tetramethyl-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.12	-0.67	-17.01	0	7	0	72	387.432	5	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.12	0.04	-28.4	1	7	1	73	388.44	5	↓ MOL2 SDF SMILES Flexibase

65331019

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4-benzyl-1-piperidyl)-(7-methylfuro[2,3-b]quinolin-2-yl)methanone (4-benzyl-1-piperidyl)-(7-methyl…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.26	11.09	-10.89	0	4	0	46	384.479	3	↓ MOL2 SDF SMILES Flexibase

65331020

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 7-methyl-N-[3-[(3S)-3-methyl-1-piperidyl]propyl]furo[2,3-b]quinoline-2-carboxamide 7-methyl-N-[3-[(3S)-3-methyl-1-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.89	8.29	-43.49	2	5	1	60	366.485	5	↓ MOL2 SDF SMILES Flexibase

65331021

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 7-methyl-N-[3-[(3R)-3-methyl-1-piperidyl]propyl]furo[2,3-b]quinoline-2-carboxamide 7-methyl-N-[3-[(3R)-3-methyl-1-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.89	8.29	-43.46	2	5	1	60	366.485	5	↓ MOL2 SDF SMILES Flexibase

65331022

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 7-methyl-N-[2-(3-thienyl)ethyl]furo[2,3-b]quinoline-2-carboxamide 7-methyl-N-[2-(3-thienyl)ethyl]f…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.84	6.45	-11.85	1	4	0	55	336.416	4	↓ MOL2 SDF SMILES Flexibase

65331023

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S)-3-(2-furyl)-1-methyl-propyl]-7-methyl-furo[2,3-b]quinoline-2-carboxamide N-[(1S)-3-(2-furyl)-1-methyl-pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.10	7.43	-12.39	1	5	0	68	348.402	5	↓ MOL2 SDF SMILES Flexibase

65331024

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-3-(2-furyl)-1-methyl-propyl]-7-methyl-furo[2,3-b]quinoline-2-carboxamide N-[(1R)-3-(2-furyl)-1-methyl-pro…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.10	7.43	-12.69	1	5	0	68	348.402	5	↓ MOL2 SDF SMILES Flexibase

65331025

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 7-methyl-N-[[1-(p-tolylmethyl)-4-piperidyl]methyl]furo[2,3-b]quinoline-2-carboxamide 7-methyl-N-[[1-(p-tolylmethyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.09	11.23	-45.56	2	5	1	60	428.556	5	↓ MOL2 SDF SMILES Flexibase

65331026

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[1-[(4-chlorophenyl)methyl]-4-piperidyl]methyl]-7-methyl-furo[2,3-b]quinoline-2-carboxamide N-[[1-[(4-chlorophenyl)methyl]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.32	11.07	-50.24	2	5	1	60	448.974	5	↓ MOL2 SDF SMILES Flexibase

65331027

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 7-methyl-N-[[1-(o-tolylmethyl)-4-piperidyl]methyl]furo[2,3-b]quinoline-2-carboxamide 7-methyl-N-[[1-(o-tolylmethyl)-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.04	11.25	-45.03	2	5	1	60	428.556	5	↓ MOL2 SDF SMILES Flexibase

65331028

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[2-(2-furyl)ethyl]-7-methyl-furo[2,3-b]quinoline-2-carboxamide N-[2-(2-furyl)ethyl]-7-methyl-fu…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.50	5.64	-12.93	1	5	0	68	320.348	4	↓ MOL2 SDF SMILES Flexibase

65331029

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[1-[(2,5-dimethylphenyl)methyl]-4-piperidyl]methyl]-7-methyl-furo[2,3-b]quinoline-2-carboxamide N-[[1-[(2,5-dimethylphenyl)methy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.47	11.83	-45.52	2	5	1	60	442.583	5	↓ MOL2 SDF SMILES Flexibase

65331030

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[[1-[(3-fluorophenyl)methyl]-4-piperidyl]methyl]-7-methyl-furo[2,3-b]quinoline-2-carboxamide N-[[1-[(3-fluorophenyl)methyl]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.78	10.62	-49.96	2	5	1	60	432.519	5	↓ MOL2 SDF SMILES Flexibase

65331031

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-methoxy-N-[[(2S)-tetrahydrofuran-2-yl]methyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[[(2S)-tetrahydrofur…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.42	2.69	-11.06	1	6	0	74	326.352	4	↓ MOL2 SDF SMILES Flexibase

65331032

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-methoxy-N-[[(2R)-tetrahydrofuran-2-yl]methyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[[(2R)-tetrahydrofur…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.42	2.72	-11.01	1	6	0	74	326.352	4	↓ MOL2 SDF SMILES Flexibase

65331033

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-(6-methoxyfuro[2,3-b]quinolin-2-yl)methanone [4-(1,3-benzodioxol-5-ylmethyl)p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.48	7.66	-53.94	1	8	1	78	446.483	4	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.48	5.44	-13.86	0	8	0	77	445.475	4	↓ MOL2 SDF SMILES Flexibase

65331034

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (6-methoxyfuro[2,3-b]quinolin-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone (6-methoxyfuro[2,3-b]quinolin-2-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.94	6.86	-11.78	0	7	0	68	417.465	4	↓ MOL2 SDF SMILES Flexibase

65331035

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4-cyclohexylpiperazin-1-yl)-(6-methoxyfuro[2,3-b]quinolin-2-yl)methanone (4-cyclohexylpiperazin-1-yl)-(6-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.09	8.45	-42.42	1	6	1	60	394.495	3	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	4.09	6.28	-8.91	0	6	0	59	393.487	3	↓ MOL2 SDF SMILES Flexibase

65331036

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[2-[benzyl(methyl)amino]ethyl]-6-methoxy-furo[2,3-b]quinoline-2-carboxamide N-[2-[benzyl(methyl)amino]ethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.48	7.27	-47.38	2	6	1	69	390.463	7	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.48	4.94	-10.95	1	6	0	68	389.455	7	↓ MOL2 SDF SMILES Flexibase

65331037

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-methoxy-N-[(3-methoxyphenyl)methyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[(3-methoxyphenyl)me…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.48	4.69	-11.51	1	6	0	74	362.385	5	↓ MOL2 SDF SMILES Flexibase

65331038

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(2-chlorophenyl)methyl]-6-methoxy-furo[2,3-b]quinoline-2-carboxamide N-[(2-chlorophenyl)methyl]-6-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.08	5.81	-10.81	1	5	0	64	366.804	4	↓ MOL2 SDF SMILES Flexibase

65331039

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(4-chlorophenyl)methyl]-6-methoxy-furo[2,3-b]quinoline-2-carboxamide N-[(4-chlorophenyl)methyl]-6-met…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.13	5.91	-10.13	1	5	0	64	366.804	4	↓ MOL2 SDF SMILES Flexibase

65331040

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: [4-(2,4-dimethylphenyl)piperazin-1-yl]-(6-methoxyfuro[2,3-b]quinolin-2-yl)methanone [4-(2,4-dimethylphenyl)piperazin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.71	9.62	-9.46	0	6	0	59	415.493	3	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.71	9.71	-38.65	1	6	1	60	416.501	3	↓ MOL2 SDF SMILES Flexibase

65331041

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-methoxy-N-[2-[(2R)-2-methyl-1-piperidyl]ethyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[2-[(2R)-2-methyl-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.32	6.04	-40.67	2	6	1	69	368.457	5	↓ MOL2 SDF SMILES Flexibase

65331042

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-methoxy-N-[2-[(2S)-2-methyl-1-piperidyl]ethyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[2-[(2S)-2-methyl-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.32	6.04	-40.68	2	6	1	69	368.457	5	↓ MOL2 SDF SMILES Flexibase

65331043

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-methoxy-N-[3-[(3R)-3-methyl-1-piperidyl]propyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[3-[(3R)-3-methyl-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.50	6.93	-43.54	2	6	1	69	382.484	6	↓ MOL2 SDF SMILES Flexibase

65331044

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-methoxy-N-[3-[(3S)-3-methyl-1-piperidyl]propyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[3-[(3S)-3-methyl-1-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.50	6.93	-43.53	2	6	1	69	382.484	6	↓ MOL2 SDF SMILES Flexibase

65331045

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[2-[cyclohexyl(methyl)amino]ethyl]-6-methoxy-furo[2,3-b]quinoline-2-carboxamide N-[2-[cyclohexyl(methyl)amino]et…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.99	6.73	-43.47	2	6	1	69	382.484	6	↓ MOL2 SDF SMILES Flexibase

65331046

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-methoxy-N-[2-(3-thienyl)ethyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[2-(3-thienyl)ethyl]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.44	5.09	-11.04	1	5	0	64	352.415	5	↓ MOL2 SDF SMILES Flexibase

65331047

Analogs

21110140

Draw Identity 99% 90% 80% 70%

Popular Name: 6-methoxy-N-phenethyl-furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-phenethyl-furo[2,3-b…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.86	6.17	-10.9	1	5	0	64	346.386	5	↓ MOL2 SDF SMILES Flexibase

65331048

Analogs

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Popular Name: 6-methoxy-N-[2-(4-methyl-1-piperidyl)ethyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[2-(4-methyl-1-piper…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.23	6.17	-43.66	2	6	1	69	368.457	5	↓ MOL2 SDF SMILES Flexibase

65331049

Analogs

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Popular Name: 6-methoxy-N-[[1-(p-tolylmethyl)-4-piperidyl]methyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[[1-(p-tolylmethyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.70	9.87	-45.78	2	6	1	69	444.555	6	↓ MOL2 SDF SMILES Flexibase

65331050

Analogs

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Popular Name: N-[[1-[(4-chlorophenyl)methyl]-4-piperidyl]methyl]-6-methoxy-furo[2,3-b]quinoline-2-carboxamide N-[[1-[(4-chlorophenyl)methyl]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.93	9.72	-50.49	2	6	1	69	464.973	6	↓ MOL2 SDF SMILES Flexibase

65331051

Analogs

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Popular Name: 6-methoxy-N-[[1-(o-tolylmethyl)-4-piperidyl]methyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[[1-(o-tolylmethyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.65	9.89	-45.32	2	6	1	69	444.555	6	↓ MOL2 SDF SMILES Flexibase

65331052

Analogs

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Popular Name: N-[[1-[(4-fluorophenyl)methyl]-4-piperidyl]methyl]-6-methoxy-furo[2,3-b]quinoline-2-carboxamide N-[[1-[(4-fluorophenyl)methyl]-4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.42	9.27	-51.56	2	6	1	69	448.518	6	↓ MOL2 SDF SMILES Flexibase

65331053

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6-methoxy-N-[4-(1-piperidylmethyl)phenyl]furo[2,3-b]quinoline-2-carboxamide 6-methoxy-N-[4-(1-piperidylmethy…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.46	9.06	-42.7	2	6	1	69	416.501	5	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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filter.purchasability = annotated
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Structural Results Found: (before additional filtering)

SQL Query Was

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