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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

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Popular Name: 6-fluoro-7-[(4-hydroxyphenyl)methylamino]-3,4-dihydro-1H-quinolin-2-one 6-fluoro-7-[(4-hydroxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.47 3.54 -9.34 3 4 0 61 286.306 3 ↓

Analogs

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Popular Name: 7-[(4-bromophenyl)methylamino]-6-fluoro-3,4-dihydro-1H-quinolin-2-one 7-[(4-bromophenyl)methylamino]-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.76 7.01 -7.83 2 3 0 41 349.203 3 ↓

Analogs

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Popular Name: 6-fluoro-7-[(4-fluorophenyl)methylamino]-3,4-dihydro-1H-quinolin-2-one 6-fluoro-7-[(4-fluorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.11 6.46 -8.41 2 3 0 41 288.297 3 ↓

Analogs

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Popular Name: 7-[(3-bromophenyl)methylamino]-6-fluoro-3,4-dihydro-1H-quinolin-2-one 7-[(3-bromophenyl)methylamino]-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.74 7 -7.89 2 3 0 41 349.203 3 ↓

Analogs

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Popular Name: 6-fluoro-7-(p-tolylmethylamino)-3,4-dihydro-1H-quinolin-2-one 6-fluoro-7-(p-tolylmethylamino)-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.40 7.06 -7.44 2 3 0 41 284.334 3 ↓

Analogs

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Popular Name: 6-fluoro-7-[(2-hydroxyphenyl)methylamino]-3,4-dihydro-1H-quinolin-2-one 6-fluoro-7-[(2-hydroxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.89 3.57 -8.6 3 4 0 61 286.306 3 ↓

Analogs

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Popular Name: 7-(benzylamino)-6-fluoro-3,4-dihydro-1H-quinolin-2-one 7-(benzylamino)-6-fluoro-3,4-dih…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.95 6.38 -7.42 2 3 0 41 270.307 3 ↓

Analogs

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Popular Name: 6-fluoro-7-[(3-hydroxyphenyl)methylamino]-3,4-dihydro-1H-quinolin-2-one 6-fluoro-7-[(3-hydroxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.45 3.53 -9.26 3 4 0 61 286.306 3 ↓

Analogs

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Popular Name: 7-[(2-bromophenyl)methylamino]-6-fluoro-3,4-dihydro-1H-quinolin-2-one 7-[(2-bromophenyl)methylamino]-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.71 6.89 -7.88 2 3 0 41 349.203 3 ↓

Analogs

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Popular Name: 7-[(3-chlorophenyl)methylamino]-6-fluoro-3,4-dihydro-1H-quinolin-2-one 7-[(3-chlorophenyl)methylamino]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.60 6.89 -7.92 2 3 0 41 304.752 3 ↓

Analogs

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Popular Name: 6-fluoro-7-[[(1S)-1-phenylethyl]amino]-3,4-dihydro-1H-quinolin-2-one 6-fluoro-7-[[(1S)-1-phenylethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.51 7.12 -7.51 2 3 0 41 284.334 3 ↓

Analogs

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Popular Name: 6-fluoro-7-[[(1R)-1-phenylethyl]amino]-3,4-dihydro-1H-quinolin-2-one 6-fluoro-7-[[(1R)-1-phenylethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.51 7.12 -7.47 2 3 0 41 284.334 3 ↓

Analogs

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Popular Name: 6-amino-7-(o-tolylmethylamino)-3,4-dihydro-1H-quinolin-2-one 6-amino-7-(o-tolylmethylamino)-3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.67 5.03 -51.22 5 4 1 69 282.367 3 ↓
Mid Mid (pH 6-8) 2.67 5.17 -7.68 4 4 0 67 281.359 3 ↓

Analogs

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Popular Name: 6-amino-7-(m-tolylmethylamino)-3,4-dihydro-1H-quinolin-2-one 6-amino-7-(m-tolylmethylamino)-3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.69 4.98 -50.82 5 4 1 69 282.367 3 ↓
Mid Mid (pH 6-8) 2.69 5.1 -7.83 4 4 0 67 281.359 3 ↓

Parameters Provided:

ring.id = 135006
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 135006 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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