UCSF
ZINC Item Suppliers, Protomers, & Similar Substances

Analogs

12350460
12350460
12350147
12350147
20371721
20371721
36654377
36654377

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Popular Name: N-(4-methylcyclohexyl)-6-morpholino-pyridin-3-amine N-(4-methylcyclohexyl)-6-morphol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.36 7.35 -27.95 2 4 1 39 276.404 3 ↓

Analogs

12350460
12350460
12350147
12350147
20371721
20371721
36654377
36654377

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Popular Name: N-(4-ethylcyclohexyl)-6-morpholino-pyridin-3-amine N-(4-ethylcyclohexyl)-6-morpholi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.04 7.71 -27.87 2 4 1 39 290.431 4 ↓

Analogs

12350147
12350147
20371721
20371721
12853914
12853914
12350460
12350460

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2R)-2-methylcyclohexyl]-6-morpholino-pyridin-3-amine N-[(1S,2R)-2-methylcyclohexyl]-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.83 7.52 -27.82 2 4 1 39 276.404 3 ↓

Analogs

12350147
12350147
20371721
20371721
12853914
12853914
12350460
12350460

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2S)-2-methylcyclohexyl]-6-morpholino-pyridin-3-amine N-[(1S,2S)-2-methylcyclohexyl]-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.83 7.22 -27.78 2 4 1 39 276.404 3 ↓

Analogs

12350147
12350147
20371721
20371721
12853914
12853914
12350460
12350460

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,2R)-2-methylcyclohexyl]-6-morpholino-pyridin-3-amine N-[(1R,2R)-2-methylcyclohexyl]-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.83 7.21 -27.77 2 4 1 39 276.404 3 ↓

Analogs

12350147
12350147
20371721
20371721
12853914
12853914
12350460
12350460

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,2S)-2-methylcyclohexyl]-6-morpholino-pyridin-3-amine N-[(1R,2S)-2-methylcyclohexyl]-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.83 7.52 -27.81 2 4 1 39 276.404 3 ↓

Analogs

36654377
36654377
12350460
12350460
12350147
12350147
20371721
20371721

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,3R)-3-methylcyclohexyl]-6-morpholino-pyridin-3-amine N-[(1S,3R)-3-methylcyclohexyl]-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.59 7.06 -27.9 2 4 1 39 276.404 3 ↓

Analogs

36654377
36654377
12350460
12350460
12350147
12350147
20371721
20371721

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,3S)-3-methylcyclohexyl]-6-morpholino-pyridin-3-amine N-[(1S,3S)-3-methylcyclohexyl]-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.59 7.36 -27.97 2 4 1 39 276.404 3 ↓

Analogs

36654377
36654377
12350460
12350460
12350147
12350147
20371721
20371721

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,3R)-3-methylcyclohexyl]-6-morpholino-pyridin-3-amine N-[(1R,3R)-3-methylcyclohexyl]-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.59 7.36 -27.94 2 4 1 39 276.404 3 ↓

Analogs

36654377
36654377
12350460
12350460
12350147
12350147
20371721
20371721

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,3S)-3-methylcyclohexyl]-6-morpholino-pyridin-3-amine N-[(1R,3S)-3-methylcyclohexyl]-6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.59 7.06 -27.89 2 4 1 39 276.404 3 ↓

Analogs

12350147
12350147
20371721
20371721
12853914
12853914
12350460
12350460

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(2S,6R)-2,6-dimethylcyclohexyl]-6-morpholino-pyridin-3-amine N-[(2S,6R)-2,6-dimethylcyclohexy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.07 8.05 -28.06 2 4 1 39 290.431 3 ↓

Analogs

12350147
12350147
20371721
20371721
12853914
12853914
12350460
12350460

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(2S,6S)-2,6-dimethylcyclohexyl]-6-morpholino-pyridin-3-amine N-[(2S,6S)-2,6-dimethylcyclohexy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.07 7.78 -27.96 2 4 1 39 290.431 3 ↓

Analogs

12350147
12350147
20371721
20371721
12853914
12853914
12350460
12350460

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(2R,6R)-2,6-dimethylcyclohexyl]-6-morpholino-pyridin-3-amine N-[(2R,6R)-2,6-dimethylcyclohexy…

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Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.07 7.78 -27.99 2 4 1 39 290.431 3 ↓

Analogs

20360261
20360261
20360232
20360232
12350460
12350460
20360203
20360203

Draw Identity 99% 90% 80% 70%

Popular Name: N-cyclohexyl-6-morpholino-pyridin-3-amine N-cyclohexyl-6-morpholino-pyridi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.59 6.41 -27.33 2 4 1 39 262.377 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2R)-2-methoxycyclohexyl]-6-morpholino-pyridin-3-amine N-[(1S,2R)-2-methoxycyclohexyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 5.81 -27.41 2 5 1 48 292.403 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,2S)-2-methoxycyclohexyl]-6-morpholino-pyridin-3-amine N-[(1S,2S)-2-methoxycyclohexyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 5.51 -27.92 2 5 1 48 292.403 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,2R)-2-methoxycyclohexyl]-6-morpholino-pyridin-3-amine N-[(1R,2R)-2-methoxycyclohexyl]-…

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Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 5.5 -27.91 2 5 1 48 292.403 4 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,2S)-2-methoxycyclohexyl]-6-morpholino-pyridin-3-amine N-[(1R,2S)-2-methoxycyclohexyl]-…

Find On: PubMed — Wikipedia — Google

Activity (Go SEA)

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.05 5.8 -27.37 2 5 1 48 292.403 4 ↓

Parameters Provided:

ring.id = 136130
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 136130 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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