ZINC 12

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.90	5.44	-14.37	2	7	0	88	349.272	4	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	1.09	4.59	-46	1	7	-1	95	348.264	4	↓ MOL2 SDF SMILES Flexibase

66206951

Analogs

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Popular Name: N-(4-methoxy-2-methyl-phenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(4-methoxy-2-methyl-phenyl)-N'…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.99	5.39	-16.06	2	8	0	98	339.355	5	↓ MOL2 SDF SMILES Flexibase

67325173

Analogs

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Popular Name: N-[4-[(1R)-1-methylpropoxy]phenyl]-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-[4-[(1R)-1-methylpropoxy]pheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.85	6.87	-15.61	2	8	0	98	367.409	7	↓ MOL2 SDF SMILES Flexibase

67325174

Analogs

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Popular Name: N-[4-[(1S)-1-methylpropoxy]phenyl]-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-[4-[(1S)-1-methylpropoxy]pheny…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.85	6.91	-16.29	2	8	0	98	367.409	7	↓ MOL2 SDF SMILES Flexibase

67325195

Analogs

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Popular Name: N-(3-allyloxyphenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(3-allyloxyphenyl)-N'-([1,2,4]…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.23	6.01	-18.41	2	8	0	98	351.366	7	↓ MOL2 SDF SMILES Flexibase

48959313

Analogs

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Popular Name: N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)-N-[2-(2,2,2-trifluoroethoxy)phenyl]oxamide N'-([1,2,4]triazolo[4,3-a]pyridi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.49	6.02	-17.55	2	8	0	98	393.325	7	↓ MOL2 SDF SMILES Flexibase

48959322

Analogs

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Popular Name: N-(3-ethynylphenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(3-ethynylphenyl)-N'-([1,2,4]t…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.29	6.39	-18.41	2	7	0	88	319.324	4	↓ MOL2 SDF SMILES Flexibase

48959438

Analogs

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Popular Name: N'-[2-chloro-5-(trifluoromethyl)phenyl]-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-[2-chloro-5-(trifluoromethyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.06	6.82	-14.94	2	7	0	88	397.744	5	↓ MOL2 SDF SMILES Flexibase

48959445

Analogs

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Popular Name: N-(2-bromophenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(2-bromophenyl)-N'-([1,2,4]tri…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.32	5.96	-14.3	2	7	0	88	374.198	4	↓ MOL2 SDF SMILES Flexibase

48959447

Analogs

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Popular Name: N'-(4-bromophenyl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-(4-bromophenyl)-N-([1,2,4]tri…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.36	5.83	-14.85	2	7	0	88	374.198	4	↓ MOL2 SDF SMILES Flexibase

48959471

Analogs

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Popular Name: N-(o-tolyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(o-tolyl)-N'-([1,2,4]triazolo[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.96	6.11	-15.28	2	7	0	88	309.329	4	↓ MOL2 SDF SMILES Flexibase

48959477

Analogs

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Popular Name: N-(2,3-dimethylphenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(2,3-dimethylphenyl)-N'-([1,2,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.36	6.62	-15.47	2	7	0	88	323.356	4	↓ MOL2 SDF SMILES Flexibase

48959479

Analogs

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Popular Name: N-(2,4-dimethylphenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(2,4-dimethylphenyl)-N'-([1,2,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.38	6.77	-15.25	2	7	0	88	323.356	4	↓ MOL2 SDF SMILES Flexibase

48959481

Analogs

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Popular Name: N'-(4-fluorophenyl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-(4-fluorophenyl)-N-([1,2,4]tr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.72	5.28	-15.42	2	7	0	88	313.292	4	↓ MOL2 SDF SMILES Flexibase

48959495

Analogs

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Popular Name: N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)-N-(2,4,6-trimethylphenyl)oxamide N'-([1,2,4]triazolo[4,3-a]pyridi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.82	7.49	-15.13	2	7	0	88	337.383	4	↓ MOL2 SDF SMILES Flexibase

48959533

Analogs

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Popular Name: N'-(3-chlorophenyl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-(3-chlorophenyl)-N-([1,2,4]tr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.21	5.73	-16.51	2	7	0	88	329.747	4	↓ MOL2 SDF SMILES Flexibase

48959538

Analogs

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Popular Name: N-(3-methylsulfanylphenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(3-methylsulfanylphenyl)-N'-([…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.96	6.22	-18.09	2	7	0	88	341.396	5	↓ MOL2 SDF SMILES Flexibase

48959554

Analogs

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Popular Name: N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)-N-[2-(trifluoromethyl)phenyl]oxamide N'-([1,2,4]triazolo[4,3-a]pyridi…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.40	6.45	-14.79	2	7	0	88	363.299	5	↓ MOL2 SDF SMILES Flexibase

48959563

Analogs

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Popular Name: N-(5-chloro-2-methoxy-phenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(5-chloro-2-methoxy-phenyl)-N'…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.22	5.15	-16.27	2	8	0	98	359.773	5	↓ MOL2 SDF SMILES Flexibase

48959582

Analogs

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Popular Name: N-(4-chloro-2-methyl-phenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(4-chloro-2-methyl-phenyl)-N'-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.61	6.61	-14.71	2	7	0	88	343.774	4	↓ MOL2 SDF SMILES Flexibase

48959587

Analogs

41179533
41179535

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Popular Name: N-(2-fluorophenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(2-fluorophenyl)-N'-([1,2,4]tr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.67	5.32	-14.9	2	7	0	88	313.292	4	↓ MOL2 SDF SMILES Flexibase

48959593

Analogs

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Popular Name: N'-(2,4-dichlorophenyl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-(2,4-dichlorophenyl)-N-([1,2,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.84	6.34	-13.16	2	7	0	88	364.192	4	↓ MOL2 SDF SMILES Flexibase

48959599

Analogs

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Popular Name: N'-(3,5-dichlorophenyl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-(3,5-dichlorophenyl)-N-([1,2,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.84	6.24	-14.32	2	7	0	88	364.192	4	↓ MOL2 SDF SMILES Flexibase

48959602

Analogs

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Popular Name: N'-(2,3,4,5,6-pentafluorophenyl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-(2,3,4,5,6-pentafluorophenyl)…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.09	5.62	-14.24	2	7	0	88	385.252	4	↓ MOL2 SDF SMILES Flexibase

48959647

Analogs

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Popular Name: N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)-N'-[4-(trifluoromethoxy)phenyl]oxamide N-([1,2,4]triazolo[4,3-a]pyridin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.52	5	-14.69	2	8	0	98	379.298	6	↓ MOL2 SDF SMILES Flexibase

48959671

Analogs

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Popular Name: N'-(2,5-difluorophenyl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-(2,5-difluorophenyl)-N-([1,2,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.81	5.38	-15.26	2	7	0	88	331.282	4	↓ MOL2 SDF SMILES Flexibase

48959685

Analogs

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Popular Name: N'-(2,3-dichlorophenyl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-(2,3-dichlorophenyl)-N-([1,2,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.81	6.3	-14.07	2	7	0	88	364.192	4	↓ MOL2 SDF SMILES Flexibase

48959688

Analogs

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Popular Name: N-(3,5-dimethylphenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(3,5-dimethylphenyl)-N'-([1,2,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.38	6.55	-15.54	2	7	0	88	323.356	4	↓ MOL2 SDF SMILES Flexibase

48959696

Analogs

41179641
41179643

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Popular Name: N'-(2,6-difluorophenyl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-(2,6-difluorophenyl)-N-([1,2,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.79	5.44	-18.06	2	7	0	88	331.282	4	↓ MOL2 SDF SMILES Flexibase

48959698

Analogs

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Popular Name: N'-(3,4-difluorophenyl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-(3,4-difluorophenyl)-N-([1,2,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	0.81	5.33	-18.1	2	7	0	88	331.282	4	↓ MOL2 SDF SMILES Flexibase

48959739

Analogs

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Popular Name: N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)-N'-[3-(trifluoromethoxy)phenyl]oxamide N-([1,2,4]triazolo[4,3-a]pyridin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.50	5	-16.73	2	8	0	98	379.298	6	↓ MOL2 SDF SMILES Flexibase

48959776

Analogs

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Popular Name: N-(2-bromo-4-methyl-phenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(2-bromo-4-methyl-phenyl)-N'-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.74	6.62	-14.09	2	7	0	88	388.225	4	↓ MOL2 SDF SMILES Flexibase

48959805

Analogs

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Popular Name: N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)-N'-(2,4,5-trichlorophenyl)oxamide N-([1,2,4]triazolo[4,3-a]pyridin…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.44	6.8	-13.32	2	7	0	88	398.637	4	↓ MOL2 SDF SMILES Flexibase

48959815

Analogs

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Popular Name: N-(3-ethylphenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(3-ethylphenyl)-N'-([1,2,4]tri…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.45	6.64	-15.13	2	7	0	88	323.356	5	↓ MOL2 SDF SMILES Flexibase

48959819

Analogs

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Popular Name: N-(2,6-diethylphenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(2,6-diethylphenyl)-N'-([1,2,4…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.35	8.3	-15.24	2	7	0	88	351.41	6	↓ MOL2 SDF SMILES Flexibase

48959821

Analogs

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Popular Name: N-(4-chloro-2-methoxy-5-methyl-phenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(4-chloro-2-methoxy-5-methyl-p…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.59	5.73	-14.75	2	8	0	98	373.8	5	↓ MOL2 SDF SMILES Flexibase

48959829

Analogs

41179793
41179795

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Popular Name: N-(2-fluoro-5-methyl-phenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(2-fluoro-5-methyl-phenyl)-N'-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.09	5.99	-15.33	2	7	0	88	327.319	4	↓ MOL2 SDF SMILES Flexibase

48959873

Analogs

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Popular Name: N'-(4-chloro-3-fluoro-phenyl)-N-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N'-(4-chloro-3-fluoro-phenyl)-N-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.32	5.78	-17.17	2	7	0	88	347.737	4	↓ MOL2 SDF SMILES Flexibase

48959965

Analogs

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Popular Name: N-(3-chloro-2,6-diethyl-phenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(3-chloro-2,6-diethyl-phenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.98	8.7	-15.17	2	7	0	88	385.855	6	↓ MOL2 SDF SMILES Flexibase

48960077

Analogs

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Popular Name: N-(2-isopropoxyphenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(2-isopropoxyphenyl)-N'-([1,2,…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.30	6.27	-15.75	2	8	0	98	353.382	6	↓ MOL2 SDF SMILES Flexibase

48960160

Analogs

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Popular Name: N-(4-bromo-2-methyl-phenyl)-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-(4-bromo-2-methyl-phenyl)-N'-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.74	6.71	-14.62	2	7	0	88	388.225	4	↓ MOL2 SDF SMILES Flexibase

48960357

Analogs

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Popular Name: N-[2-(difluoromethylsulfanyl)phenyl]-N'-([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)oxamide N-[2-(difluoromethylsulfanyl)phe…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.50	6.61	-16.13	2	7	0	88	377.376	6	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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