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Popular Name: 3-(chloromethyl)-5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazole 3-(chloromethyl)-5-[(1S)-tetrali…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.96 6.3 -7.07 0 3 0 39 248.713 2 ↓

Analogs

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Popular Name: 3-(chloromethyl)-5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazole 3-(chloromethyl)-5-[(1R)-tetrali…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.96 6.3 -6.71 0 3 0 39 248.713 2 ↓

Analogs

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Popular Name: [5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]methanamine [5-[(1S)-tetralin-1-yl]-1,2,4-ox…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 3.11 -46.09 3 4 1 67 230.291 2 ↓
Hi High (pH 8-9.5) 1.57 2.71 -7.31 2 4 0 65 229.283 2 ↓

Analogs

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Popular Name: [5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]methanamine [5-[(1R)-tetralin-1-yl]-1,2,4-ox…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 3.11 -46.34 3 4 1 67 230.291 2 ↓
Hi High (pH 8-9.5) 1.57 2.71 -7.12 2 4 0 65 229.283 2 ↓

Analogs

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Popular Name: (1S)-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]ethanamine (1S)-1-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.25 3.64 -43.09 3 4 1 67 244.318 2 ↓
Hi High (pH 8-9.5) 0.25 3.32 -7.07 2 4 0 65 243.31 2 ↓

Analogs

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Popular Name: (1R)-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]ethanamine (1R)-1-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.25 3.64 -42.82 3 4 1 67 244.318 2 ↓
Hi High (pH 8-9.5) 0.25 3.27 -7.5 2 4 0 65 243.31 2 ↓

Analogs

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Popular Name: (1S)-1-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]ethanamine (1S)-1-[5-[(1S)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.25 3.64 -42.81 3 4 1 67 244.318 2 ↓
Hi High (pH 8-9.5) 0.25 3.32 -7.26 2 4 0 65 243.31 2 ↓

Analogs

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Popular Name: (1R)-1-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]ethanamine (1R)-1-[5-[(1S)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.25 3.64 -43.12 3 4 1 67 244.318 2 ↓
Hi High (pH 8-9.5) 0.25 3.27 -7.56 2 4 0 65 243.31 2 ↓

Analogs

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Popular Name: (1S)-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1S)-1-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.75 4.45 -41.75 3 4 1 67 258.345 3 ↓
Hi High (pH 8-9.5) 0.75 4.14 -6.86 2 4 0 65 257.337 3 ↓

Analogs

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Popular Name: (1R)-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1R)-1-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.75 4.45 -41.45 3 4 1 67 258.345 3 ↓
Hi High (pH 8-9.5) 0.75 4.16 -5.63 2 4 0 65 257.337 3 ↓

Analogs

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Popular Name: (1S)-1-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1S)-1-[5-[(1S)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.75 4.45 -41.43 3 4 1 67 258.345 3 ↓
Hi High (pH 8-9.5) 0.75 4.14 -7.03 2 4 0 65 257.337 3 ↓

Analogs

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Popular Name: (1R)-1-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1R)-1-[5-[(1S)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.75 4.45 -41.75 3 4 1 67 258.345 3 ↓
Hi High (pH 8-9.5) 0.75 4.16 -5.67 2 4 0 65 257.337 3 ↓

Analogs

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Popular Name: (1S)-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]butan-1-amine (1S)-1-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.31 5.22 -42.9 3 4 1 67 272.372 4 ↓
Hi High (pH 8-9.5) 1.31 4.9 -6.82 2 4 0 65 271.364 4 ↓

Analogs

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Popular Name: (1R)-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]butan-1-amine (1R)-1-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.31 5.22 -42.53 3 4 1 67 272.372 4 ↓
Hi High (pH 8-9.5) 1.31 4.93 -5.49 2 4 0 65 271.364 4 ↓

Analogs

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Popular Name: (1S)-1-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]butan-1-amine (1S)-1-[5-[(1S)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.31 5.22 -42.53 3 4 1 67 272.372 4 ↓
Hi High (pH 8-9.5) 1.31 4.9 -6.93 2 4 0 65 271.364 4 ↓

Analogs

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Popular Name: (1R)-1-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]butan-1-amine (1R)-1-[5-[(1S)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.31 5.22 -42.82 3 4 1 67 272.372 4 ↓
Hi High (pH 8-9.5) 1.31 4.93 -5.57 2 4 0 65 271.364 4 ↓

Analogs

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Popular Name: (1S)-2-methyl-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1S)-2-methyl-1-[5-[(1R)-tetrali…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.99 5.17 -41.74 3 4 1 67 272.372 3 ↓

Analogs

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Popular Name: (1R)-2-methyl-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1R)-2-methyl-1-[5-[(1R)-tetrali…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.99 4.7 -41.77 3 4 1 67 272.372 3 ↓

Analogs

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Popular Name: (1S)-2-methyl-1-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1S)-2-methyl-1-[5-[(1S)-tetrali…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.99 5.17 -41.35 3 4 1 67 272.372 3 ↓

Analogs

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Popular Name: (1R)-2-methyl-1-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1R)-2-methyl-1-[5-[(1S)-tetrali…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.99 4.7 -42.21 3 4 1 67 272.372 3 ↓

Analogs

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Popular Name: (1S)-2,2-dimethyl-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1S)-2,2-dimethyl-1-[5-[(1R)-tet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 5.31 -42.09 3 4 1 67 286.399 3 ↓

Analogs

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Popular Name: (1R)-2,2-dimethyl-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1R)-2,2-dimethyl-1-[5-[(1R)-tet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 5.29 -41.67 3 4 1 67 286.399 3 ↓

Analogs

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Popular Name: (1S)-2,2-dimethyl-1-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1S)-2,2-dimethyl-1-[5-[(1S)-tet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 5.31 -41.7 3 4 1 67 286.399 3 ↓

Analogs

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Popular Name: (1R)-2,2-dimethyl-1-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (1R)-2,2-dimethyl-1-[5-[(1S)-tet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.57 5.29 -42.06 3 4 1 67 286.399 3 ↓

Analogs

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Popular Name: 2-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-2-amine 2-[5-[(1R)-tetralin-1-yl]-1,2,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.57 4.23 -42.64 3 4 1 67 258.345 2 ↓
Hi High (pH 8-9.5) 2.57 3.96 -5.79 2 4 0 65 257.337 2 ↓

Analogs

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Popular Name: 2-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-2-amine 2-[5-[(1S)-tetralin-1-yl]-1,2,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.57 4.23 -42.65 3 4 1 67 258.345 2 ↓
Hi High (pH 8-9.5) 2.57 3.96 -5.82 2 4 0 65 257.337 2 ↓

Analogs

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Popular Name: 3-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]pentan-3-amine 3-[5-[(1R)-tetralin-1-yl]-1,2,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.58 5.72 -41.66 3 4 1 67 286.399 4 ↓

Analogs

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Popular Name: 3-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]pentan-3-amine 3-[5-[(1S)-tetralin-1-yl]-1,2,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.58 5.72 -41.67 3 4 1 67 286.399 4 ↓

Analogs

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Popular Name: (2S)-2-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine (2S)-2-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.07 4.97 -41.16 3 4 1 67 272.372 3 ↓
Hi High (pH 8-9.5) 3.07 4.69 -7.29 2 4 0 65 271.364 3 ↓

Analogs

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Popular Name: (2R)-2-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine (2R)-2-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.07 4.85 -40.8 3 4 1 67 272.372 3 ↓
Hi High (pH 8-9.5) 3.07 4.62 -5.68 2 4 0 65 271.364 3 ↓

Analogs

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Popular Name: (2S)-2-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine (2S)-2-[5-[(1S)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.07 4.97 -41.18 3 4 1 67 272.372 3 ↓
Hi High (pH 8-9.5) 3.07 4.69 -7.01 2 4 0 65 271.364 3 ↓

Analogs

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Popular Name: (2R)-2-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]butan-2-amine (2R)-2-[5-[(1S)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.07 4.85 -41.19 3 4 1 67 272.372 3 ↓
Hi High (pH 8-9.5) 3.07 4.62 -5.82 2 4 0 65 271.364 3 ↓

Analogs

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Popular Name: 2-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]ethanamine 2-[5-[(1S)-tetralin-1-yl]-1,2,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 3.82 -48.55 3 4 1 67 244.318 3 ↓

Analogs

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Popular Name: 2-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]ethanamine 2-[5-[(1R)-tetralin-1-yl]-1,2,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 3.82 -48.85 3 4 1 67 244.318 3 ↓

Analogs

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Popular Name: N-methyl-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]methanamine N-methyl-1-[5-[(1R)-tetralin-1-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.94 4.98 -40.38 2 4 1 56 244.318 3 ↓
Hi High (pH 8-9.5) 1.94 3.54 -6.9 1 4 0 51 243.31 3 ↓

Analogs

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Popular Name: N-methyl-1-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]methanamine N-methyl-1-[5-[(1S)-tetralin-1-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.94 4.98 -40.6 2 4 1 56 244.318 3 ↓
Hi High (pH 8-9.5) 1.94 3.54 -6.84 1 4 0 51 243.31 3 ↓

Analogs

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Popular Name: N-methyl-2-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]ethanamine N-methyl-2-[5-[(1R)-tetralin-1-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 5.7 -43.47 2 4 1 56 258.345 4 ↓

Analogs

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Popular Name: N-methyl-2-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]ethanamine N-methyl-2-[5-[(1S)-tetralin-1-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 5.7 -43.76 2 4 1 56 258.345 4 ↓

Analogs

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Popular Name: N-[[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]methyl]ethanamine N-[[5-[(1R)-tetralin-1-yl]-1,2,4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.32 5.84 -39.36 2 4 1 56 258.345 4 ↓
Hi High (pH 8-9.5) 2.32 4.47 -6.73 1 4 0 51 257.337 4 ↓

Analogs

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Popular Name: N-[[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]methyl]ethanamine N-[[5-[(1S)-tetralin-1-yl]-1,2,4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.32 5.84 -39.52 2 4 1 56 258.345 4 ↓
Hi High (pH 8-9.5) 2.32 4.47 -6.65 1 4 0 51 257.337 4 ↓

Analogs

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Popular Name: N-[[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]methyl]propan-2-amine N-[[5-[(1R)-tetralin-1-yl]-1,2,4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.61 6.37 -37.32 2 4 1 56 272.372 4 ↓
Hi High (pH 8-9.5) 2.61 5.17 -6.52 1 4 0 51 271.364 4 ↓

Analogs

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Popular Name: N-[[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]methyl]propan-2-amine N-[[5-[(1S)-tetralin-1-yl]-1,2,4…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.61 6.37 -37.54 2 4 1 56 272.372 4 ↓
Hi High (pH 8-9.5) 2.61 5.17 -6.45 1 4 0 51 271.364 4 ↓

Analogs

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Popular Name: 3-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine 3-[5-[(1S)-tetralin-1-yl]-1,2,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.64 4.6 -47.85 3 4 1 67 258.345 4 ↓

Analogs

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Popular Name: 3-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine 3-[5-[(1R)-tetralin-1-yl]-1,2,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.64 4.6 -48.36 3 4 1 67 258.345 4 ↓

Analogs

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Popular Name: (2S)-2-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (2S)-2-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.69 4.31 -48.24 3 4 1 67 258.345 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (2R)-2-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.69 4.31 -48.58 3 4 1 67 258.345 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2S)-2-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (2S)-2-[5-[(1S)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.69 4.31 -48.58 3 4 1 67 258.345 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-2-[5-[(1S)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-1-amine (2R)-2-[5-[(1S)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.69 4.31 -48.22 3 4 1 67 258.345 3 ↓

Analogs

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Popular Name: (2S)-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-2-amine (2S)-1-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.77 4.54 -41.72 3 4 1 67 258.345 3 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2R)-1-[5-[(1R)-tetralin-1-yl]-1,2,4-oxadiazol-3-yl]propan-2-amine (2R)-1-[5-[(1R)-tetralin-1-yl]-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.77 4.42 -39.13 3 4 1 67 258.345 3 ↓

Parameters Provided:

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Structural Results Found: (before additional filtering)

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