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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

35016653
35016653
37119228
37119228
37119229
37119229

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Popular Name: N-[(1S)-1-(4-fluorophenyl)-2-methyl-propyl]tetrahydrothiopyran-4-amine N-[(1S)-1-(4-fluorophenyl)-2-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.88 9.31 -43.79 2 1 1 17 268.421 4 ↓

Analogs

37119228
37119228
37119229
37119229
35016651
35016651

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Popular Name: N-[(1R)-1-(4-fluorophenyl)-2-methyl-propyl]tetrahydrothiopyran-4-amine N-[(1R)-1-(4-fluorophenyl)-2-met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.88 9 -45.9 2 1 1 17 268.421 4 ↓

Analogs

35016858
35016858

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Popular Name: N-[(1S)-1-(3-fluoro-4-methoxy-phenyl)ethyl]tetrahydrothiopyran-4-amine N-[(1S)-1-(3-fluoro-4-methoxy-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 7.33 -50.04 2 2 1 26 270.393 4 ↓

Analogs

35016856
35016856

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Popular Name: N-[(1R)-1-(3-fluoro-4-methoxy-phenyl)ethyl]tetrahydrothiopyran-4-amine N-[(1R)-1-(3-fluoro-4-methoxy-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 7.32 -50 2 2 1 26 270.393 4 ↓

Analogs

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Popular Name: N-[(3-nitrophenyl)methyl]tetrahydrothiopyran-4-amine N-[(3-nitrophenyl)methyl]tetrahy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 8.06 -58.1 2 4 1 62 253.347 4 ↓
Hi High (pH 8-9.5) 2.35 6.86 -8.93 1 4 0 58 252.339 4 ↓

Analogs

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Popular Name: N-[(1S)-1-(5-fluoro-2-methoxy-phenyl)ethyl]tetrahydrothiopyran-4-amine N-[(1S)-1-(5-fluoro-2-methoxy-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 7.5 -41.31 2 2 1 26 270.393 4 ↓

Analogs

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Popular Name: N-[(1R)-1-(5-fluoro-2-methoxy-phenyl)ethyl]tetrahydrothiopyran-4-amine N-[(1R)-1-(5-fluoro-2-methoxy-ph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.12 7.45 -41.15 2 2 1 26 270.393 4 ↓

Analogs

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Popular Name: N-[(1S)-2-ethyl-1-phenyl-butyl]tetrahydrothiopyran-4-amine N-[(1S)-2-ethyl-1-phenyl-butyl]t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.72 10.47 -38.29 2 1 1 17 278.485 6 ↓

Analogs

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Popular Name: N-[(1R)-2-ethyl-1-phenyl-butyl]tetrahydrothiopyran-4-amine N-[(1R)-2-ethyl-1-phenyl-butyl]t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.72 10.36 -38.51 2 1 1 17 278.485 6 ↓

Analogs

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Popular Name: N-[[4-(trifluoromethyl)phenyl]methyl]tetrahydrothiopyran-4-amine N-[[4-(trifluoromethyl)phenyl]me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.31 8.35 -51.28 2 1 1 17 276.347 4 ↓
Hi High (pH 8-9.5) 3.31 7.15 -3.83 1 1 0 12 275.339 4 ↓

Analogs

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Popular Name: (2S)-2-phenyl-2-(tetrahydrothiopyran-4-ylamino)ethanol (2S)-2-phenyl-2-(tetrahydrothiop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.96 4.76 -39.96 3 2 1 37 238.376 4 ↓
Hi High (pH 8-9.5) 1.96 3.92 -4.61 2 2 0 32 237.368 4 ↓

Analogs

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Popular Name: (2R)-2-phenyl-2-(tetrahydrothiopyran-4-ylamino)ethanol (2R)-2-phenyl-2-(tetrahydrothiop…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.96 4.75 -40.03 3 2 1 37 238.376 4 ↓
Hi High (pH 8-9.5) 1.96 3.71 -3.86 2 2 0 32 237.368 4 ↓

Analogs

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Popular Name: [4-[(4-bromophenyl)methyl-methyl-amino]tetrahydrothiopyran-4-yl]methanol [4-[(4-bromophenyl)methyl-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.90 6.61 -39.24 2 2 1 25 331.299 4 ↓
Hi High (pH 8-9.5) 2.90 4.52 -4.38 1 2 0 23 330.291 4 ↓

Analogs

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Popular Name: N-[(2,4-dimethoxyphenyl)methyl]tetrahydrothiopyran-4-amine N-[(2,4-dimethoxyphenyl)methyl]t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.45 6 -41.44 2 3 1 35 268.402 5 ↓

Analogs

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Popular Name: N-[(1S)-1-(3,4-dimethoxyphenyl)ethyl]tetrahydrothiopyran-4-amine N-[(1S)-1-(3,4-dimethoxyphenyl)e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 7.16 -48.41 2 3 1 35 282.429 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R)-1-(3,4-dimethoxyphenyl)ethyl]tetrahydrothiopyran-4-amine N-[(1R)-1-(3,4-dimethoxyphenyl)e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 7.15 -48.38 2 3 1 35 282.429 5 ↓

Analogs

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Popular Name: N-[(3,4-difluorophenyl)methyl]tetrahydrothiopyran-4-amine N-[(3,4-difluorophenyl)methyl]te…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.67 7.47 -54.17 2 1 1 17 244.33 3 ↓

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Structural Results Found: (before additional filtering)

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