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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

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Popular Name: 6-[[methyl-[2-(3-methylphenoxy)ethyl]amino]methyl]-2-phenyl-pyrazolo[3,4-d]pyridazin-7-one 6-[[methyl-[2-(3-methylphenoxy)e…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.20 11.39 -46.36 1 7 1 66 390.467 7 ↓
Mid Mid (pH 6-8) 3.20 8.86 -23.43 0 7 0 65 389.459 7 ↓

Analogs

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Popular Name: 6-[(8-fluoro-6-methyl-3,4-dihydro-2H-quinolin-1-yl)methyl]-2-phenyl-pyrazolo[3,4-d]pyridazin-7-one 6-[(8-fluoro-6-methyl-3,4-dihydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.81 11.43 -18.55 0 6 0 56 389.434 3 ↓

Analogs

8594002
8594002

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Popular Name: 3-(3,4-dimethyl-7-oxo-2-phenyl-pyrazolo[4,3-d]pyridazin-6-yl)-N-[(4-isopropoxyphenyl)methyl]propanam 3-(3,4-dimethyl-7-oxo-2-phenyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 9.97 -22.97 1 8 0 91 459.55 8 ↓

Analogs

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Popular Name: 3-(3,4-dimethyl-7-oxo-2-phenyl-pyrazolo[4,3-d]pyridazin-6-yl)-N-[2-(o-tolyl)ethyl]propanamide 3-(3,4-dimethyl-7-oxo-2-phenyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.10 10.31 -23.68 1 7 0 82 429.524 7 ↓

Analogs

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Popular Name: 3-(3,4-dimethyl-7-oxo-2-phenyl-pyrazolo[4,3-d]pyridazin-6-yl)-N-(o-tolylmethyl)propanamide 3-(3,4-dimethyl-7-oxo-2-phenyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.69 9.87 -22.1 1 7 0 82 415.497 6 ↓

Analogs

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Popular Name: N-[2-(2-chlorophenyl)ethyl]-3-(3,4-dimethyl-7-oxo-2-phenyl-pyrazolo[4,3-d]pyridazin-6-yl)propanamide N-[2-(2-chlorophenyl)ethyl]-3-(3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 10.3 -24.77 1 7 0 82 449.942 7 ↓

Analogs

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Popular Name: N-[2-(2,5-dimethoxyphenyl)ethyl]-3-(3,4-dimethyl-7-oxo-2-phenyl-pyrazolo[4,3-d]pyridazin-6-yl)propan N-[2-(2,5-dimethoxyphenyl)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.74 8.52 -26.12 1 9 0 100 475.549 9 ↓

Analogs

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Popular Name: 3-(3,4-dimethyl-7-oxo-2-phenyl-pyrazolo[4,3-d]pyridazin-6-yl)-N-[2-(2-methoxyphenyl)ethyl]propanamid 3-(3,4-dimethyl-7-oxo-2-phenyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.71 9.24 -25.31 1 8 0 91 445.523 8 ↓

Analogs

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Popular Name: 3-(3,4-dimethyl-7-oxo-2-phenyl-pyrazolo[4,3-d]pyridazin-6-yl)-N-[2-(4-ethoxyphenyl)ethyl]propanamide 3-(3,4-dimethyl-7-oxo-2-phenyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.13 10.07 -25.22 1 8 0 91 459.55 9 ↓

Analogs

20563560
20563560

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Popular Name: N-[(2,5-dimethoxyphenyl)methyl]-3-(3,4-dimethyl-7-oxo-2-phenyl-pyrazolo[4,3-d]pyridazin-6-yl)propana N-[(2,5-dimethoxyphenyl)methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.33 7.73 -25.02 1 9 0 100 461.522 8 ↓

Analogs

8593999
8593999

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Popular Name: 3-(3,4-dimethyl-7-oxo-2-phenyl-pyrazolo[4,3-d]pyridazin-6-yl)-N-[(3,4,5-trimethoxyphenyl)methyl]prop 3-(3,4-dimethyl-7-oxo-2-phenyl-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.92 8.24 -26.36 1 10 0 110 491.548 9 ↓

Analogs

15936772
15936772

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Popular Name: (2S)-N-(2-chlorophenyl)-2-(3,4-dimethyl-7-oxo-2-phenyl-pyrazolo[4,3-d]pyridazin-6-yl)propanamide (2S)-N-(2-chlorophenyl)-2-(3,4-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.31 9.87 -22.5 1 7 0 82 421.888 4 ↓

Analogs

15936771
15936771

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Popular Name: (2R)-N-(2-chlorophenyl)-2-(3,4-dimethyl-7-oxo-2-phenyl-pyrazolo[4,3-d]pyridazin-6-yl)propanamide (2R)-N-(2-chlorophenyl)-2-(3,4-d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.31 9.87 -21.78 1 7 0 82 421.888 4 ↓

Analogs

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Popular Name: N-(3-methoxypropyl)-2-[methyl-[(7-oxo-2-phenyl-pyrazolo[3,4-d]pyridazin-6-yl)methyl]amino]acetamide N-(3-methoxypropyl)-2-[methyl-[(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.95 6.24 -47.59 2 9 1 95 385.448 9 ↓
Mid Mid (pH 6-8) 0.95 3.82 -25.61 1 9 0 94 384.44 9 ↓

Analogs

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Popular Name: 2-[(7-oxo-2-phenyl-pyrazolo[3,4-d]pyridazin-6-yl)methyl-propyl-amino]acetonitrile 2-[(7-oxo-2-phenyl-pyrazolo[3,4-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.75 6.52 -23.13 0 7 0 80 322.372 6 ↓

Analogs

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Popular Name: 6-[[methyl(propyl)amino]methyl]-2-phenyl-pyrazolo[3,4-d]pyridazin-7-one 6-[[methyl(propyl)amino]methyl]-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.97 8.57 -40.33 1 6 1 57 298.37 5 ↓
Hi High (pH 8-9.5) 1.97 6.09 -18.04 0 6 0 56 297.362 5 ↓

Analogs

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Popular Name: 6-[[cyclopropylmethyl(ethyl)amino]methyl]-2-phenyl-pyrazolo[3,4-d]pyridazin-7-one 6-[[cyclopropylmethyl(ethyl)amin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.34 10.02 -38.27 1 6 1 57 324.408 6 ↓
Hi High (pH 8-9.5) 2.34 7.91 -18.36 0 6 0 56 323.4 6 ↓

Analogs

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Popular Name: 6-[[cyclopentyl(cyclopropyl)amino]methyl]-2-phenyl-pyrazolo[3,4-d]pyridazin-7-one 6-[[cyclopentyl(cyclopropyl)amin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.86 10.86 -36.68 1 6 1 57 350.446 5 ↓

Analogs

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Popular Name: 6-[[(2-ethylthiazol-5-yl)methyl-methyl-amino]methyl]-2-phenyl-pyrazolo[3,4-d]pyridazin-7-one 6-[[(2-ethylthiazol-5-yl)methyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.94 7.3 -21.77 0 7 0 69 380.477 6 ↓
Mid Mid (pH 6-8) 1.94 9.79 -47.14 1 7 1 70 381.485 6 ↓

Analogs

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Popular Name: 6-[[[(1S)-1-methylbutyl]-pentyl-amino]methyl]-2-phenyl-pyrazolo[3,4-d]pyridazin-7-one 6-[[[(1S)-1-methylbutyl]-pentyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.80 13.35 -39.17 1 6 1 57 382.532 10 ↓
Hi High (pH 8-9.5) 4.80 10.09 -18.39 0 6 0 56 381.524 10 ↓

Parameters Provided:

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 142739 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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