UCSF
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Analogs

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Popular Name: N-(4-fluorophenyl)-2-[4-[2-(2,2,4-trioxo-1H-benzo[d]thiazin-3-yl)acetyl]piperazin-1-yl]acetamide N-(4-fluorophenyl)-2-[4-[2-(2,2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.11 4.23 -30.44 1 9 0 107 474.514 5 ↓
Lo Low (pH 4.5-6) 1.11 6.37 -66.92 2 9 1 108 475.522 5 ↓

Analogs

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Popular Name: 3-[2-(o-tolyl)-2-oxo-ethyl]-2,2-dioxo-1H-benzo[d]thiazin-4-one 3-[2-(o-tolyl)-2-oxo-ethyl]-2,2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.08 6.32 -20.36 0 5 0 72 329.377 3 ↓

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.10 6.29 -15.61 0 6 0 81 345.376 4 ↓

Analogs

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Popular Name: 3-[2-(2,2,4-trioxo-1H-benzo[d]thiazin-3-yl)ethoxy]benzonitrile 3-[2-(2,2,4-trioxo-1H-benzo[d]th…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.95 6.72 -17.82 0 6 0 87 342.376 4 ↓

Analogs

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Popular Name: 3-[2-(4-chlorophenyl)-2-oxo-ethyl]-2,2-dioxo-1H-benzo[d]thiazin-4-one 3-[2-(4-chlorophenyl)-2-oxo-ethy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.36 6.18 -19.89 0 5 0 72 349.795 3 ↓

Analogs

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Popular Name: 2,2-dioxo-3-(8-quinolylmethyl)-1H-benzo[d]thiazin-4-one 2,2-dioxo-3-(8-quinolylmethyl)-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.89 7.08 -16.67 0 5 0 67 338.388 2 ↓

Analogs

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Popular Name: methyl methyl

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.64 5.16 -17.5 0 7 0 94 349.364 4 ↓

Analogs

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Popular Name: 2,2-dioxo-3-[2-oxo-2-(2-oxoimidazolidin-1-yl)ethyl]-1H-benzo[d]thiazin-4-one 2,2-dioxo-3-[2-oxo-2-(2-oxoimida…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.95 0.6 -23.33 1 8 0 104 323.33 2 ↓

Analogs

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Popular Name: 3-[(4-nitrophenyl)methyl]-2,2-dioxo-1H-benzo[d]thiazin-4-one 3-[(4-nitrophenyl)methyl]-2,2-di…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.89 6.36 -14.77 0 7 0 100 332.337 3 ↓

Analogs

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Popular Name: 3-[(5-nitro-3-thienyl)methyl]-2,2-dioxo-1H-benzo[d]thiazin-4-one 3-[(5-nitro-3-thienyl)methyl]-2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.60 5.54 -15.7 0 7 0 100 338.366 3 ↓

Analogs

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Popular Name: 3-[(3-tert-butyl-1,2,4-oxadiazol-5-yl)methyl]-2,2-dioxo-1H-benzo[d]thiazin-4-one 3-[(3-tert-butyl-1,2,4-oxadiazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.74 2.75 -18.98 0 7 0 93 335.385 3 ↓

Analogs

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Popular Name: 3-[(3-methylisoxazol-5-yl)methyl]-2,2-dioxo-1H-benzo[d]thiazin-4-one 3-[(3-methylisoxazol-5-yl)methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.88 3.43 -18.17 0 6 0 80 292.316 2 ↓

Analogs

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Popular Name: N-(4-fluorophenyl)-2-(2,2,4-trioxo-1H-benzo[d]thiazin-3-yl)acetamide N-(4-fluorophenyl)-2-(2,2,4-trio…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.87 4.22 -22.59 1 6 0 84 348.355 3 ↓

Analogs

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Popular Name: N-(2,5-dimethylpyrazol-3-yl)-2-(2,2,4-trioxo-1H-benzo[d]thiazin-3-yl)acetamide N-(2,5-dimethylpyrazol-3-yl)-2-(…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.50 3.38 -25.65 1 8 0 101 348.384 3 ↓

Analogs

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Popular Name: 3-[2-(3,5-dimethylphenoxy)ethyl]-2,2-dioxo-1H-benzo[d]thiazin-4-one 3-[2-(3,5-dimethylphenoxy)ethyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.04 7.67 -16.82 0 5 0 64 345.42 4 ↓

Analogs

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Popular Name: 3-[(1-methylpyrazol-4-yl)methyl]-2,2-dioxo-1H-benzo[d]thiazin-4-one 3-[(1-methylpyrazol-4-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.31 3.45 -16.17 0 6 0 72 291.332 2 ↓

Analogs

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Popular Name: 3-[(5-methylisoxazol-3-yl)methyl]-2,2-dioxo-1H-benzo[d]thiazin-4-one 3-[(5-methylisoxazol-3-yl)methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.88 3.41 -18.52 0 6 0 80 292.316 2 ↓

Analogs

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Popular Name: 3-[2-(2,5-dimethyl-1H-pyrrol-3-yl)-2-oxo-ethyl]-2,2-dioxo-1H-benzo[d]thiazin-4-one 3-[2-(2,5-dimethyl-1H-pyrrol-3-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.97 4.82 -21.67 1 6 0 87 332.381 3 ↓

Analogs

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Popular Name: 3-[(5-isobutyl-1,2,4-oxadiazol-3-yl)methyl]-2,2-dioxo-1H-benzo[d]thiazin-4-one 3-[(5-isobutyl-1,2,4-oxadiazol-3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.33 3.31 -18.79 0 7 0 93 335.385 4 ↓

Analogs

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Popular Name: N-[4-[2-(2,2,4-trioxo-1H-benzo[d]thiazin-3-yl)acetyl]phenyl]propanamide N-[4-[2-(2,2,4-trioxo-1H-benzo[d…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.74 5.36 -24.91 1 7 0 101 386.429 5 ↓

Analogs

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Popular Name: N-[(1S,2R,3R)-2,3-dimethylcyclohexyl]-2-(2,2,4-trioxo-1H-benzo[d]thiazin-3-yl)acetamide N-[(1S,2R,3R)-2,3-dimethylcycloh…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.53 4.86 -21.5 1 6 0 84 364.467 3 ↓

Analogs

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Popular Name: N-[(1S,2R,3S)-2,3-dimethylcyclohexyl]-2-(2,2,4-trioxo-1H-benzo[d]thiazin-3-yl)acetamide N-[(1S,2R,3S)-2,3-dimethylcycloh…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.53 5.65 -20.78 1 6 0 84 364.467 3 ↓

Analogs

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Popular Name: N-[(1R,2R,3R)-2,3-dimethylcyclohexyl]-2-(2,2,4-trioxo-1H-benzo[d]thiazin-3-yl)acetamide N-[(1R,2R,3R)-2,3-dimethylcycloh…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.53 5.02 -21.48 1 6 0 84 364.467 3 ↓

Analogs

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Popular Name: N-[(1R,2R,3S)-2,3-dimethylcyclohexyl]-2-(2,2,4-trioxo-1H-benzo[d]thiazin-3-yl)acetamide N-[(1R,2R,3S)-2,3-dimethylcycloh…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.53 5.25 -21.58 1 6 0 84 364.467 3 ↓

Analogs

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Popular Name: 2-[3-[(2,2,4-trioxo-1H-benzo[d]thiazin-3-yl)methyl]phenoxy]acetamide 2-[3-[(2,2,4-trioxo-1H-benzo[d]t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.70 3.06 -25.06 2 7 0 107 360.391 5 ↓

Analogs

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Popular Name: 2,2-dioxo-3-[[3-(2-thienyl)-1,2,4-oxadiazol-5-yl]methyl]-1H-benzo[d]thiazin-4-one 2,2-dioxo-3-[[3-(2-thienyl)-1,2,…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.82 3.16 -21.36 0 7 0 93 361.404 3 ↓

Parameters Provided:

ring.id = 144050
filter.purchasability = annotated
page.format = targets
page.num = 1

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 144050 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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