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Analogs

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Popular Name: 4-chloro-2-[(2-chloro-4-fluoro-phenyl)methyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidine 4-chloro-2-[(2-chloro-4-fluoro-p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.53 9.11 -6.43 0 2 0 26 297.16 2 ↓

Analogs

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Popular Name: 2-[(2-chloro-4-fluoro-phenyl)methyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine 2-[(2-chloro-4-fluoro-phenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.33 7.47 -6.87 2 3 0 52 277.73 2 ↓
Mid Mid (pH 6-8) 3.33 7.65 -28.54 3 3 1 53 278.738 2 ↓

Analogs

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Popular Name: 2-[(2-chloro-4-fluoro-phenyl)methyl]-N-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine 2-[(2-chloro-4-fluoro-phenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.70 8.52 -6.93 1 3 0 38 291.757 3 ↓
Mid Mid (pH 6-8) 3.70 9.13 -30.94 2 3 1 39 292.765 3 ↓

Analogs

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Popular Name: 2-[(2-chloro-4-fluoro-phenyl)methyl]-N-ethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine 2-[(2-chloro-4-fluoro-phenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.08 9.36 -6.55 1 3 0 38 305.784 4 ↓
Mid Mid (pH 6-8) 4.08 9.98 -30.64 2 3 1 39 306.792 4 ↓

Analogs

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Popular Name: [2-[(2-chloro-4-fluoro-phenyl)methyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]hydrazine [2-[(2-chloro-4-fluoro-phenyl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 7.34 -7.65 3 4 0 64 292.745 3 ↓

Analogs

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Popular Name: 4-chloro-2-(1-methyl-1-phenyl-ethyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine 4-chloro-2-(1-methyl-1-phenyl-et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.18 9.46 -6.12 0 2 0 26 272.779 2 ↓

Analogs

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Popular Name: 2-(1-methyl-1-phenyl-ethyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine 2-(1-methyl-1-phenyl-ethyl)-6,7-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.99 8.15 -26.21 3 3 1 53 254.357 2 ↓
Mid Mid (pH 6-8) 2.99 7.83 -6.91 2 3 0 52 253.349 2 ↓

Analogs

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Popular Name: N-methyl-2-(1-methyl-1-phenyl-ethyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine N-methyl-2-(1-methyl-1-phenyl-et…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.36 9.31 -25.39 2 3 1 39 268.384 3 ↓
Mid Mid (pH 6-8) 3.36 8.98 -7.09 1 3 0 38 267.376 3 ↓

Analogs

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Popular Name: N-ethyl-2-(1-methyl-1-phenyl-ethyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine N-ethyl-2-(1-methyl-1-phenyl-eth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.74 10.16 -24.96 2 3 1 39 282.411 4 ↓
Mid Mid (pH 6-8) 3.74 9.88 -6.74 1 3 0 38 281.403 4 ↓

Analogs

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Popular Name: [2-(1-methyl-1-phenyl-ethyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]hydrazine [2-(1-methyl-1-phenyl-ethyl)-6,7…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.75 7.71 -7.58 3 4 0 64 268.364 3 ↓

Analogs

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Popular Name: 2-(1-ethyl-1-phenyl-propyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine 2-(1-ethyl-1-phenyl-propyl)-6,7-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.99 8.74 -22.83 3 3 1 53 282.411 4 ↓
Mid Mid (pH 6-8) 3.99 9.67 -6.4 2 3 0 52 281.403 4 ↓

Analogs

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Popular Name: 4-chloro-2-[(3,5-difluorophenyl)methyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidine 4-chloro-2-[(3,5-difluorophenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.01 8.51 -5.86 0 2 0 26 280.705 2 ↓

Parameters Provided:

ring.id = 148087
filter.purchasability = annotated
page.format = targets
page.num = 1

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SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 148087 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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