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Analogs

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Popular Name: 4-bromo-1-[(1-ethylimidazol-2-yl)methyl]indoline-2,3-dione 4-bromo-1-[(1-ethylimidazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.79 7.57 -21.25 0 5 0 57 334.173 3 ↓
Mid Mid (pH 6-8) 1.79 8.54 -41.17 1 5 1 58 335.181 3 ↓

Analogs

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Popular Name: 5-bromo-1-[(1-ethylimidazol-2-yl)methyl]indoline-2,3-dione 5-bromo-1-[(1-ethylimidazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.82 7.58 -17.85 0 5 0 57 334.173 3 ↓
Mid Mid (pH 6-8) 1.82 8.53 -39.29 1 5 1 58 335.181 3 ↓

Analogs

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Popular Name: 5-chloro-1-[(1-ethylimidazol-2-yl)methyl]indoline-2,3-dione 5-chloro-1-[(1-ethylimidazol-2-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.68 7.48 -18.02 0 5 0 57 289.722 3 ↓
Mid Mid (pH 6-8) 1.68 8.43 -39.25 1 5 1 58 290.73 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-5-methyl-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.46 7.63 -19.06 0 5 0 57 269.304 3 ↓
Mid Mid (pH 6-8) 1.46 8.6 -37.06 1 5 1 58 270.312 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-6-fluoro-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.17 7.03 -15.65 0 5 0 57 273.267 3 ↓
Mid Mid (pH 6-8) 1.17 7.98 -35.68 1 5 1 58 274.275 3 ↓

Analogs

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Popular Name: 6-bromo-1-[(1-ethylimidazol-2-yl)methyl]indoline-2,3-dione 6-bromo-1-[(1-ethylimidazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.82 7.57 -15.17 0 5 0 57 334.173 3 ↓
Mid Mid (pH 6-8) 1.82 8.54 -35.07 1 5 1 58 335.181 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-7-methyl-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.43 7.84 -9.81 0 5 0 57 269.304 3 ↓
Mid Mid (pH 6-8) 1.43 8.02 -35.65 1 5 1 58 270.312 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-5,7-dimethyl-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.83 8.49 -9.33 0 5 0 57 283.331 3 ↓
Mid Mid (pH 6-8) 1.83 8.68 -35.41 1 5 1 58 284.339 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-6,7-dimethyl-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.83 8.37 -9.62 0 5 0 57 283.331 3 ↓
Mid Mid (pH 6-8) 1.83 8.58 -35.16 1 5 1 58 284.339 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-6-methoxy-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.06 6.27 -17.2 0 6 0 66 285.303 4 ↓
Mid Mid (pH 6-8) 1.06 7.23 -35.06 1 6 1 67 286.311 4 ↓

Analogs

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Popular Name: 6-chloro-1-[(1-ethylimidazol-2-yl)methyl]indoline-2,3-dione 6-chloro-1-[(1-ethylimidazol-2-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.68 7.48 -15.39 0 5 0 57 289.722 3 ↓
Mid Mid (pH 6-8) 1.68 8.42 -35.24 1 5 1 58 290.73 3 ↓

Analogs

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Popular Name: 7-bromo-1-[(1-ethylimidazol-2-yl)methyl]-5-fluoro-indoline-2,3-dione 7-bromo-1-[(1-ethylimidazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.93 7.9 -7.87 0 5 0 57 352.163 3 ↓
Mid Mid (pH 6-8) 0.93 8 -32.58 1 5 1 58 353.171 3 ↓

Analogs

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Popular Name: 7-bromo-1-[(1-ethylimidazol-2-yl)methyl]indoline-2,3-dione 7-bromo-1-[(1-ethylimidazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.79 7.82 -10.4 0 5 0 57 334.173 3 ↓
Mid Mid (pH 6-8) 1.79 7.95 -32.23 1 5 1 58 335.181 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-4,6-dimethyl-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.83 8.28 -18.66 0 5 0 57 283.331 3 ↓
Mid Mid (pH 6-8) 1.83 9.25 -36.23 1 5 1 58 284.339 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-5-methoxy-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.06 6.26 -19.98 0 6 0 66 285.303 4 ↓
Mid Mid (pH 6-8) 1.06 7.21 -39.64 1 6 1 67 286.311 4 ↓

Analogs

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Popular Name: 5-ethyl-1-[(1-ethylimidazol-2-yl)methyl]indoline-2,3-dione 5-ethyl-1-[(1-ethylimidazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.92 8.59 -9.1 0 5 0 57 283.331 4 ↓
Mid Mid (pH 6-8) 1.92 9.37 -37.41 1 5 1 58 284.339 4 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-4,7-dimethyl-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.83 8.48 -9.78 0 5 0 57 283.331 3 ↓
Mid Mid (pH 6-8) 1.83 8.68 -35.51 1 5 1 58 284.339 3 ↓

Analogs

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Popular Name: 7-chloro-1-[(1-ethylimidazol-2-yl)methyl]indoline-2,3-dione 7-chloro-1-[(1-ethylimidazol-2-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.66 7.8 -9.41 0 5 0 57 289.722 3 ↓
Mid Mid (pH 6-8) 1.66 7.97 -32.52 1 5 1 58 290.73 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-5,7-difluoro-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.29 7.32 -7.67 0 5 0 57 291.257 3 ↓
Mid Mid (pH 6-8) 0.29 8.03 -32.64 1 5 1 58 292.265 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-7-fluoro-5-methyl-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.55 7.91 -9.49 0 5 0 57 287.294 3 ↓
Mid Mid (pH 6-8) 1.55 8.63 -31.21 1 5 1 58 288.302 3 ↓

Analogs

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Popular Name: 5-bromo-1-[(1-ethylimidazol-2-yl)methyl]-7-methyl-indoline-2,3-dione 5-bromo-1-[(1-ethylimidazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.19 8.44 -7.95 0 5 0 57 348.2 3 ↓
Mid Mid (pH 6-8) 2.19 8.63 -36.89 1 5 1 58 349.208 3 ↓

Analogs

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Popular Name: 4-chloro-1-[(1-ethylimidazol-2-yl)methyl]-7-fluoro-indoline-2,3-dione 4-chloro-1-[(1-ethylimidazol-2-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.78 7.76 -9.72 0 5 0 57 307.712 3 ↓
Mid Mid (pH 6-8) 1.78 8.47 -34.11 1 5 1 58 308.72 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-4,6-difluoro-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.26 7.1 -17.01 0 5 0 57 291.257 3 ↓
Mid Mid (pH 6-8) 1.26 8.06 -39.84 1 5 1 58 292.265 3 ↓

Analogs

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Popular Name: 5-bromo-1-[(1-ethylimidazol-2-yl)methyl]-6-fluoro-indoline-2,3-dione 5-bromo-1-[(1-ethylimidazol-2-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.91 7.61 -14.4 0 5 0 57 352.163 3 ↓
Mid Mid (pH 6-8) 1.91 8.58 -38.21 1 5 1 58 353.171 3 ↓

Analogs

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Popular Name: 4-chloro-1-[(1-ethylimidazol-2-yl)methyl]indoline-2,3-dione 4-chloro-1-[(1-ethylimidazol-2-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.66 7.47 -21.46 0 5 0 57 289.722 3 ↓
Mid Mid (pH 6-8) 1.66 8.42 -41.26 1 5 1 58 290.73 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.03 6.96 -19.72 0 5 0 57 255.277 3 ↓
Mid Mid (pH 6-8) 1.03 7.93 -37.14 1 5 1 58 256.285 3 ↓

Analogs

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Popular Name: 1-[(1-ethylimidazol-2-yl)methyl]-5-fluoro-indoline-2,3-dione 1-[(1-ethylimidazol-2-yl)methyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.20 7.03 -18.58 0 5 0 57 273.267 3 ↓
Mid Mid (pH 6-8) 0.20 7.99 -39.98 1 5 1 58 274.275 3 ↓

Analogs

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Popular Name: 1-[[1-(difluoromethyl)imidazol-2-yl]methyl]indoline-2,3-dione 1-[[1-(difluoromethyl)imidazol-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.21 6.05 -16.58 0 5 0 57 277.23 3 ↓
Lo Low (pH 4.5-6) 1.21 7.12 -40.76 1 5 1 58 278.238 3 ↓

Analogs

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Popular Name: 4-bromo-1-[(1-methylimidazol-2-yl)methyl]indoline-2,3-dione 4-bromo-1-[(1-methylimidazol-2-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.42 6.95 -11.18 0 5 0 57 320.146 2 ↓
Mid Mid (pH 6-8) 1.42 7.36 -44.45 1 5 1 58 321.154 2 ↓

Analogs

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Popular Name: 5-bromo-1-[(1-methylimidazol-2-yl)methyl]indoline-2,3-dione 5-bromo-1-[(1-methylimidazol-2-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.44 6.95 -8.97 0 5 0 57 320.146 2 ↓
Mid Mid (pH 6-8) 1.44 7.37 -42.24 1 5 1 58 321.154 2 ↓

Analogs

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Popular Name: 1-[(1-methylimidazol-2-yl)methyl]indoline-2,3-dione 1-[(1-methylimidazol-2-yl)methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.65 6.34 -10.58 0 5 0 57 241.25 2 ↓
Mid Mid (pH 6-8) 0.65 6.75 -40.04 1 5 1 58 242.258 2 ↓

Analogs

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Popular Name: 5-chloro-1-[(1-methylimidazol-2-yl)methyl]indoline-2,3-dione 5-chloro-1-[(1-methylimidazol-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.31 6.85 -9.08 0 5 0 57 275.695 2 ↓
Mid Mid (pH 6-8) 1.31 7.26 -42.31 1 5 1 58 276.703 2 ↓

Analogs

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Popular Name: 6-fluoro-1-[(1-methylimidazol-2-yl)methyl]indoline-2,3-dione 6-fluoro-1-[(1-methylimidazol-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.79 6.41 -9.12 0 5 0 57 259.24 2 ↓
Mid Mid (pH 6-8) 0.79 6.82 -37.81 1 5 1 58 260.248 2 ↓

Analogs

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Popular Name: 5-fluoro-1-[(1-methylimidazol-2-yl)methyl]indoline-2,3-dione 5-fluoro-1-[(1-methylimidazol-2-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.18 6.41 -9.41 0 5 0 57 259.24 2 ↓
Mid Mid (pH 6-8) -0.18 6.82 -43.07 1 5 1 58 260.248 2 ↓

Analogs

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Popular Name: 6-bromo-1-[(1-methylimidazol-2-yl)methyl]indoline-2,3-dione 6-bromo-1-[(1-methylimidazol-2-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.44 6.95 -8.67 0 5 0 57 320.146 2 ↓
Mid Mid (pH 6-8) 1.44 7.37 -37.03 1 5 1 58 321.154 2 ↓

Analogs

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Popular Name: 4-bromo-1-[[1-(difluoromethyl)imidazol-2-yl]methyl]indoline-2,3-dione 4-bromo-1-[[1-(difluoromethyl)im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.97 6.66 -17.7 0 5 0 57 356.126 3 ↓
Lo Low (pH 4.5-6) 1.97 7.72 -44.97 1 5 1 58 357.134 3 ↓

Analogs

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Popular Name: 4-bromo-1-[(5-chloro-1-methyl-imidazol-2-yl)methyl]indoline-2,3-dione 4-bromo-1-[(5-chloro-1-methyl-im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.22 7.31 -10.62 0 5 0 57 354.591 2 ↓
Lo Low (pH 4.5-6) 2.22 7.72 -46.65 1 5 1 58 355.599 2 ↓

Analogs

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Popular Name: 5-bromo-1-[[1-(difluoromethyl)imidazol-2-yl]methyl]indoline-2,3-dione 5-bromo-1-[[1-(difluoromethyl)im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.00 6.67 -14.46 0 5 0 57 356.126 3 ↓
Lo Low (pH 4.5-6) 2.00 7.72 -42.93 1 5 1 58 357.134 3 ↓

Analogs

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Popular Name: 1-[(5-chloro-1-methyl-imidazol-2-yl)methyl]indoline-2,3-dione 1-[(5-chloro-1-methyl-imidazol-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.46 6.7 -9.67 0 5 0 57 275.695 2 ↓
Lo Low (pH 4.5-6) 1.46 7.11 -41.92 1 5 1 58 276.703 2 ↓

Analogs

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Popular Name: 5-chloro-1-[[1-(difluoromethyl)imidazol-2-yl]methyl]indoline-2,3-dione 5-chloro-1-[[1-(difluoromethyl)i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.87 6.56 -14.64 0 5 0 57 311.675 3 ↓
Lo Low (pH 4.5-6) 1.87 7.63 -42.91 1 5 1 58 312.683 3 ↓

Analogs

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Popular Name: 5-chloro-1-[(5-chloro-1-methyl-imidazol-2-yl)methyl]indoline-2,3-dione 5-chloro-1-[(5-chloro-1-methyl-i…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.11 7.21 -8.5 0 5 0 57 310.14 2 ↓
Lo Low (pH 4.5-6) 2.11 7.62 -44.44 1 5 1 58 311.148 2 ↓

Analogs

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Popular Name: 1-[(5-chloro-1-methyl-imidazol-2-yl)methyl]-5-methyl-indoline-2,3-dione 1-[(5-chloro-1-methyl-imidazol-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.88 7.32 -8.95 0 5 0 57 289.722 2 ↓
Lo Low (pH 4.5-6) 1.88 7.82 -42.09 1 5 1 58 290.73 2 ↓

Analogs

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Popular Name: 1-[[1-(difluoromethyl)imidazol-2-yl]methyl]-6-fluoro-indoline-2,3-dione 1-[[1-(difluoromethyl)imidazol-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.35 6.12 -13.1 0 5 0 57 295.22 3 ↓
Lo Low (pH 4.5-6) 1.35 7.19 -39.03 1 5 1 58 296.228 3 ↓

Analogs

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Popular Name: 1-[(5-chloro-1-methyl-imidazol-2-yl)methyl]-6-fluoro-indoline-2,3-dione 1-[(5-chloro-1-methyl-imidazol-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.60 6.77 -8.15 0 5 0 57 293.685 2 ↓
Lo Low (pH 4.5-6) 1.60 7.18 -39.47 1 5 1 58 294.693 2 ↓

Analogs

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Popular Name: 6-bromo-1-[[1-(difluoromethyl)imidazol-2-yl]methyl]indoline-2,3-dione 6-bromo-1-[[1-(difluoromethyl)im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.00 6.67 -12.41 0 5 0 57 356.126 3 ↓
Lo Low (pH 4.5-6) 2.00 7.73 -38.36 1 5 1 58 357.134 3 ↓

Analogs

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Popular Name: 6-bromo-1-[(5-chloro-1-methyl-imidazol-2-yl)methyl]indoline-2,3-dione 6-bromo-1-[(5-chloro-1-methyl-im…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.24 7.32 -7.7 0 5 0 57 354.591 2 ↓
Lo Low (pH 4.5-6) 2.24 7.72 -38.55 1 5 1 58 355.599 2 ↓

Analogs

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Popular Name: 1-[(5-chloro-1-methyl-imidazol-2-yl)methyl]-5,7-dimethyl-indoline-2,3-dione 1-[(5-chloro-1-methyl-imidazol-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.26 8.25 -8 0 5 0 57 303.749 2 ↓
Lo Low (pH 4.5-6) 2.26 8.25 -37.48 1 5 1 58 304.757 2 ↓

Analogs

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Popular Name: 5,7-dimethyl-1-[(1-methylimidazol-2-yl)methyl]indoline-2,3-dione 5,7-dimethyl-1-[(1-methylimidazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.46 7.88 -8.85 0 5 0 57 269.304 2 ↓
Mid Mid (pH 6-8) 1.46 7.87 -36.65 1 5 1 58 270.312 2 ↓

Analogs

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Popular Name: 1-[(5-chloro-1-methyl-imidazol-2-yl)methyl]-6,7-dimethyl-indoline-2,3-dione 1-[(5-chloro-1-methyl-imidazol-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.26 8.13 -8.22 0 5 0 57 303.749 2 ↓
Lo Low (pH 4.5-6) 2.26 8.14 -37.2 1 5 1 58 304.757 2 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 6,7-dimethyl-1-[(1-methylimidazol-2-yl)methyl]indoline-2,3-dione 6,7-dimethyl-1-[(1-methylimidazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.46 7.78 -9.14 0 5 0 57 269.304 2 ↓
Mid Mid (pH 6-8) 1.46 7.78 -36.42 1 5 1 58 270.312 2 ↓

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