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Analogs

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Popular Name: (4-chlorophenyl)-[4-(2-ethyl-5,6-dimethyl-thieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (4-chlorophenyl)-[4-(2-ethyl-5,6…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.91 -1.55 -12.23 0 5 0 49 414.962 3 ↓

Analogs

35866857
35866857

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Popular Name: [4-(2-ethyl-5,6-dimethyl-thieno[2,3-d]pyrimidin-4-yl)piperazino]-(p-tolyl)methanone [4-(2-ethyl-5,6-dimethyl-thieno[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.68 -0.99 -13.17 0 5 0 49 394.544 3 ↓

Analogs

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Popular Name: [4-(5,6-dimethyl-2-propyl-thieno[2,3-d]pyrimidin-4-yl)piperazino]-(p-tolyl)methanone [4-(5,6-dimethyl-2-propyl-thieno…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.19 -0.87 -12.95 0 5 0 49 408.571 4 ↓

Analogs

35525569
35525569

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Popular Name: [4-(5,6-dimethyl-2-propyl-thieno[2,3-d]pyrimidin-4-yl)piperazino]-(4-methoxyphenyl)methanone [4-(5,6-dimethyl-2-propyl-thieno…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.79 -1.15 -14.03 0 6 0 58 424.57 5 ↓

Analogs

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Popular Name: [4-(2-isopropyl-5,6-dimethyl-thieno[2,3-d]pyrimidin-4-yl)piperazino]-(4-methoxyphenyl)methanone [4-(2-isopropyl-5,6-dimethyl-thi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.78 -0.93 -14 0 6 0 58 424.57 4 ↓

Analogs

25458926
25458926

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Popular Name: (4-bromophenyl)-[4-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (4-bromophenyl)-[4-(5,6-dimethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.38 10.77 -10.57 0 5 0 49 431.359 2 ↓

Analogs

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Popular Name: [4-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]-(3,4,5-trimethoxyphenyl)methanone [4-(5,6-dimethylthieno[2,3-d]pyr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.21 9.68 -13.5 0 8 0 77 442.541 5 ↓

Analogs

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Popular Name: (4-chlorophenyl)-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (4-chlorophenyl)-[4-(2,5,6-trime…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.34 -1.57 -12.38 0 5 0 49 400.935 2 ↓

Analogs

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Popular Name: (2-chlorophenyl)-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (2-chlorophenyl)-[4-(2,5,6-trime…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.29 -1.55 -15.02 0 5 0 49 400.935 2 ↓

Analogs

4882361
4882361
25458926
25458926

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Popular Name: phenyl-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone phenyl-[4-(2,5,6-trimethylthieno…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.66 9.94 -13.54 0 5 0 49 366.49 2 ↓

Analogs

4882361
4882361

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Popular Name: p-tolyl-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone p-tolyl-[4-(2,5,6-trimethylthien…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.11 -1.1 -13.15 0 5 0 49 380.517 2 ↓

Analogs

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Popular Name: o-tolyl-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone o-tolyl-[4-(2,5,6-trimethylthien…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.06 -1.04 -12.34 0 5 0 49 380.517 2 ↓

Analogs

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Popular Name: (4-tert-butylphenyl)-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (4-tert-butylphenyl)-[4-(2,5,6-t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.37 -0.27 -12.58 0 5 0 49 422.598 3 ↓

Analogs

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Popular Name: (4-bromophenyl)-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (4-bromophenyl)-[4-(2,5,6-trimet…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.47 10.81 -12.28 0 5 0 49 445.386 2 ↓

Analogs

8272670
8272670

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Popular Name: (4-methoxyphenyl)-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (4-methoxyphenyl)-[4-(2,5,6-trim…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.72 -1.39 -14.13 0 6 0 58 396.516 3 ↓

Analogs

4882361
4882361
25458926
25458926

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Popular Name: (4-fluorophenyl)-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (4-fluorophenyl)-[4-(2,5,6-trime…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.83 -0.69 -12.74 0 5 0 49 384.48 2 ↓

Analogs

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Popular Name: (3,4,5-trimethoxyphenyl)-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (3,4,5-trimethoxyphenyl)-[4-(2,5…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.29 9.36 -15.93 0 8 0 77 456.568 5 ↓

Analogs

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Popular Name: m-tolyl-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone m-tolyl-[4-(2,5,6-trimethylthien…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.09 -1.1 -13.41 0 5 0 49 380.517 2 ↓

Analogs

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Popular Name: (3-chlorophenyl)-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (3-chlorophenyl)-[4-(2,5,6-trime…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.32 -1.57 -14.38 0 5 0 49 400.935 2 ↓

Analogs

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Popular Name: (2-fluorophenyl)-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (2-fluorophenyl)-[4-(2,5,6-trime…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.78 -0.72 -17.35 0 5 0 49 384.48 2 ↓

Analogs

4882361
4882361
25458926
25458926

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Popular Name: (3-fluorophenyl)-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (3-fluorophenyl)-[4-(2,5,6-trime…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 -0.68 -15.18 0 5 0 49 384.48 2 ↓

Analogs

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Popular Name: (2,6-dimethoxyphenyl)-[4-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone (2,6-dimethoxyphenyl)-[4-(2,5,6-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.68 9.11 -16.98 0 7 0 68 426.542 4 ↓

Analogs

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Popular Name: (3-hydroxyphenyl)-(4-thieno[2,3-d]pyrimidin-4-ylpiperazin-1-yl)methanone (3-hydroxyphenyl)-(4-thieno[2,3-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.47 5.98 -13.57 1 6 0 70 340.408 2 ↓

Parameters Provided:

ring.id = 156632
filter.purchasability = annotated
page.format = targets
page.num = 1

Structural Results Found: (before additional filtering)

SQL Query Was

SELECT DISTINCT(ci.sub_id_fk) AS sub_id FROM catalog_item AS ci INNER JOIN catalog AS c ON ci.cat_id_fk=c.cat_id INNER JOIN hasring AS hr ON ci.sub_id_fk=hr.sub_id_fk INNER JOIN rings AS r ON hr.rings_fk=r.rings_id  WHERE r.rings_id = 156632 AND c.free = 1 AND c.purchasable = 0    LIMIT 50

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