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Popular Name: 2-thiomorpholinothiazole-5-carbaldehyde 2-thiomorpholinothiazole-5-carba…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 5.08 -8.23 0 3 0 33 214.315 2 ↓

Analogs

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Popular Name: 1-(2-thiomorpholinothiazol-5-yl)ethanone 1-(2-thiomorpholinothiazol-5-yl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.62 5.79 -9.31 0 3 0 33 228.342 2 ↓

Analogs

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Popular Name: 1-(4-methyl-2-thiomorpholino-thiazol-5-yl)ethanone 1-(4-methyl-2-thiomorpholino-thi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.84 6.44 -8.04 0 3 0 33 242.369 2 ↓

Analogs

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Popular Name: (1R)-1-(4-methyl-2-thiomorpholino-thiazol-5-yl)ethanamine (1R)-1-(4-methyl-2-thiomorpholin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.19 4.55 -45.86 3 3 1 44 244.409 2 ↓
Mid Mid (pH 6-8) -0.19 4.2 -5.46 2 3 0 42 243.401 2 ↓

Analogs

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Popular Name: (1S)-1-(4-methyl-2-thiomorpholino-thiazol-5-yl)ethanamine (1S)-1-(4-methyl-2-thiomorpholin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.19 4.56 -45.46 3 3 1 44 244.409 2 ↓
Mid Mid (pH 6-8) -0.19 4.22 -5.76 2 3 0 42 243.401 2 ↓

Analogs

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Popular Name: (2-thiomorpholinothiazol-5-yl)methanamine (2-thiomorpholinothiazol-5-yl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.90 3.37 -46.83 3 3 1 44 216.355 2 ↓
Mid Mid (pH 6-8) 0.90 2.97 -5.42 2 3 0 42 215.347 2 ↓

Analogs

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Popular Name: (1S)-1-(2-thiomorpholinothiazol-5-yl)ethanamine (1S)-1-(2-thiomorpholinothiazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.42 4.04 -45.36 3 3 1 44 230.382 2 ↓
Mid Mid (pH 6-8) -0.42 3.7 -4.59 2 3 0 42 229.374 2 ↓

Analogs

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Popular Name: (1R)-1-(2-thiomorpholinothiazol-5-yl)ethanamine (1R)-1-(2-thiomorpholinothiazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.42 4.04 -45.27 3 3 1 44 230.382 2 ↓
Mid Mid (pH 6-8) -0.42 3.72 -5.33 2 3 0 42 229.374 2 ↓

Analogs

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Popular Name: (1R)-N-methyl-1-(4-methyl-2-thiomorpholino-thiazol-5-yl)ethanamine (1R)-N-methyl-1-(4-methyl-2-thio…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.06 6.26 -40.45 2 3 1 33 258.436 3 ↓
Hi High (pH 8-9.5) 2.06 4.98 -5.44 1 3 0 28 257.428 3 ↓

Analogs

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Popular Name: (1S)-N-methyl-1-(4-methyl-2-thiomorpholino-thiazol-5-yl)ethanamine (1S)-N-methyl-1-(4-methyl-2-thio…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.06 6.28 -40.11 2 3 1 33 258.436 3 ↓
Hi High (pH 8-9.5) 2.06 4.98 -4.78 1 3 0 28 257.428 3 ↓

Analogs

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Popular Name: (1S)-N-ethyl-1-(4-methyl-2-thiomorpholino-thiazol-5-yl)ethanamine (1S)-N-ethyl-1-(4-methyl-2-thiom…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.44 7.1 -38.95 2 3 1 33 272.463 4 ↓
Hi High (pH 8-9.5) 2.44 5.91 -5.23 1 3 0 28 271.455 4 ↓

Analogs

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Popular Name: (1R)-N-ethyl-1-(4-methyl-2-thiomorpholino-thiazol-5-yl)ethanamine (1R)-N-ethyl-1-(4-methyl-2-thiom…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.44 7.12 -38.85 2 3 1 33 272.463 4 ↓
Hi High (pH 8-9.5) 2.44 5.91 -4.6 1 3 0 28 271.455 4 ↓

Analogs

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Popular Name: N-[(1S)-1-(4-methyl-2-thiomorpholino-thiazol-5-yl)ethyl]propan-1-amine N-[(1S)-1-(4-methyl-2-thiomorpho…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.94 7.86 -39.56 2 3 1 33 286.49 5 ↓
Hi High (pH 8-9.5) 2.94 6.67 -5.15 1 3 0 28 285.482 5 ↓

Analogs

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Popular Name: N-[(1R)-1-(4-methyl-2-thiomorpholino-thiazol-5-yl)ethyl]propan-1-amine N-[(1R)-1-(4-methyl-2-thiomorpho…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.94 7.88 -39.56 2 3 1 33 286.49 5 ↓
Hi High (pH 8-9.5) 2.94 6.66 -4.5 1 3 0 28 285.482 5 ↓

Analogs

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Popular Name: N-methyl-1-(2-thiomorpholinothiazol-5-yl)methanamine N-methyl-1-(2-thiomorpholinothia…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.28 5.25 -41.31 2 3 1 33 230.382 3 ↓
Hi High (pH 8-9.5) 1.28 3.8 -4.91 1 3 0 28 229.374 3 ↓

Analogs

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Popular Name: N-[(2-thiomorpholinothiazol-5-yl)methyl]ethanamine N-[(2-thiomorpholinothiazol-5-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.66 6.11 -40.43 2 3 1 33 244.409 4 ↓
Hi High (pH 8-9.5) 1.66 4.74 -4.76 1 3 0 28 243.401 4 ↓

Analogs

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Popular Name: N-[(2-thiomorpholinothiazol-5-yl)methyl]propan-1-amine N-[(2-thiomorpholinothiazol-5-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.16 6.86 -41.26 2 3 1 33 258.436 5 ↓
Hi High (pH 8-9.5) 2.16 5.5 -4.7 1 3 0 28 257.428 5 ↓

Analogs

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Popular Name: N-[(2-thiomorpholinothiazol-5-yl)methyl]propan-2-amine N-[(2-thiomorpholinothiazol-5-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.95 6.64 -38.75 2 3 1 33 258.436 4 ↓
Hi High (pH 8-9.5) 1.95 5.43 -4.62 1 3 0 28 257.428 4 ↓

Analogs

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Popular Name: 2-methyl-N-[(2-thiomorpholinothiazol-5-yl)methyl]propan-2-amine 2-methyl-N-[(2-thiomorpholinothi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.46 7.07 -36.92 2 3 1 33 272.463 4 ↓
Hi High (pH 8-9.5) 2.46 5.81 -4.53 1 3 0 28 271.455 4 ↓

Analogs

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Popular Name: 2-methyl-N-[(2-thiomorpholinothiazol-5-yl)methyl]propan-1-amine 2-methyl-N-[(2-thiomorpholinothi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 7.55 -41.19 2 3 1 33 272.463 5 ↓
Hi High (pH 8-9.5) 2.40 6.18 -4.56 1 3 0 28 271.455 5 ↓

Analogs

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Popular Name: 2-methoxy-N-[(2-thiomorpholinothiazol-5-yl)methyl]ethanamine 2-methoxy-N-[(2-thiomorpholinoth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.26 5.24 -40.86 2 4 1 42 274.435 6 ↓
Mid Mid (pH 6-8) 1.26 3.89 -5.81 1 4 0 37 273.427 6 ↓

Analogs

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Popular Name: (1S)-N-methyl-1-(2-thiomorpholinothiazol-5-yl)ethanamine (1S)-N-methyl-1-(2-thiomorpholin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.84 5.79 -40.03 2 3 1 33 244.409 3 ↓
Hi High (pH 8-9.5) 1.84 4.51 -4.26 1 3 0 28 243.401 3 ↓

Analogs

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Popular Name: (1R)-N-methyl-1-(2-thiomorpholinothiazol-5-yl)ethanamine (1R)-N-methyl-1-(2-thiomorpholin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.84 5.78 -39.88 2 3 1 33 244.409 3 ↓
Hi High (pH 8-9.5) 1.84 4.53 -5.09 1 3 0 28 243.401 3 ↓

Analogs

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Popular Name: (1S)-N-ethyl-1-(2-thiomorpholinothiazol-5-yl)ethanamine (1S)-N-ethyl-1-(2-thiomorpholino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.21 6.63 -38.66 2 3 1 33 258.436 4 ↓
Hi High (pH 8-9.5) 2.21 5.46 -4.86 1 3 0 28 257.428 4 ↓

Analogs

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Popular Name: (1R)-N-ethyl-1-(2-thiomorpholinothiazol-5-yl)ethanamine (1R)-N-ethyl-1-(2-thiomorpholino…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.21 6.63 -38.57 2 3 1 33 258.436 4 ↓
Hi High (pH 8-9.5) 2.21 5.43 -4.09 1 3 0 28 257.428 4 ↓

Analogs

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Popular Name: N-[(1S)-1-(2-thiomorpholinothiazol-5-yl)ethyl]propan-1-amine N-[(1S)-1-(2-thiomorpholinothiaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.72 7.39 -39.39 2 3 1 33 272.463 5 ↓
Hi High (pH 8-9.5) 2.72 6.22 -4.69 1 3 0 28 271.455 5 ↓

Analogs

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Popular Name: N-[(1R)-1-(2-thiomorpholinothiazol-5-yl)ethyl]propan-1-amine N-[(1R)-1-(2-thiomorpholinothiaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.72 7.39 -39.28 2 3 1 33 272.463 5 ↓
Hi High (pH 8-9.5) 2.72 6.18 -3.99 1 3 0 28 271.455 5 ↓

Analogs

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Popular Name: (1R)-1-(4-methyl-2-thiomorpholino-thiazol-5-yl)ethanol (1R)-1-(4-methyl-2-thiomorpholin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 3.93 -6.16 1 3 0 36 244.385 2 ↓
Lo Low (pH 4.5-6) 1.51 4.33 -27.16 2 3 1 38 245.393 2 ↓

Analogs

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Popular Name: (1S)-1-(4-methyl-2-thiomorpholino-thiazol-5-yl)ethanol (1S)-1-(4-methyl-2-thiomorpholin…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 3.95 -6.24 1 3 0 36 244.385 2 ↓
Lo Low (pH 4.5-6) 1.51 4.35 -27.12 2 3 1 38 245.393 2 ↓

Analogs

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Popular Name: (2-thiomorpholinothiazol-5-yl)methanol (2-thiomorpholinothiazol-5-yl)me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.06 2.63 -7.48 1 3 0 36 216.331 2 ↓
Lo Low (pH 4.5-6) 1.06 3.09 -29.35 2 3 1 38 217.339 2 ↓

Analogs

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Popular Name: (1S)-1-(2-thiomorpholinothiazol-5-yl)ethanol (1S)-1-(2-thiomorpholinothiazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.28 3.43 -7.13 1 3 0 36 230.358 2 ↓
Lo Low (pH 4.5-6) 1.28 3.9 -30.12 2 3 1 38 231.366 2 ↓

Analogs

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Popular Name: (1R)-1-(2-thiomorpholinothiazol-5-yl)ethanol (1R)-1-(2-thiomorpholinothiazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.28 3.42 -7.13 1 3 0 36 230.358 2 ↓
Lo Low (pH 4.5-6) 1.28 3.88 -30.14 2 3 1 38 231.366 2 ↓

Analogs

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Popular Name: 4-methyl-2-thiomorpholino-thiazole-5-carbaldehyde 4-methyl-2-thiomorpholino-thiazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.73 5.63 -9.28 0 3 0 33 228.342 2 ↓

Analogs

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Popular Name: 4-ethyl-2-thiomorpholino-thiazole-5-carbaldehyde 4-ethyl-2-thiomorpholino-thiazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.30 6.36 -8.75 0 3 0 33 242.369 3 ↓

Analogs

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Popular Name: 4-propyl-2-thiomorpholino-thiazole-5-carbaldehyde 4-propyl-2-thiomorpholino-thiazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.81 7.14 -8.44 0 3 0 33 256.396 4 ↓

Analogs

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Popular Name: 4-tert-butyl-2-thiomorpholino-thiazole-5-carbaldehyde 4-tert-butyl-2-thiomorpholino-th…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.46 7.41 -7.97 0 3 0 33 270.423 3 ↓

Analogs

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Popular Name: 4-methyl-2-thiomorpholino-thiazole-5-carboxylic 4-methyl-2-thiomorpholino-thiazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.51 6.45 -48.73 0 4 -1 56 243.333 2 ↓
Mid Mid (pH 6-8) 1.51 6.82 -39.71 1 4 0 58 244.341 2 ↓

Analogs

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Popular Name: 4-tert-butyl-2-thiomorpholino-thiazole-5-carboxylic 4-tert-butyl-2-thiomorpholino-th…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.24 8.2 -46.94 0 4 -1 56 285.414 3 ↓
Mid Mid (pH 6-8) 3.24 8.51 -36.31 1 4 0 58 286.422 3 ↓

Analogs

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Popular Name: 4-ethyl-2-thiomorpholino-thiazole-5-carboxylic 4-ethyl-2-thiomorpholino-thiazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.09 7.17 -49.1 0 4 -1 56 257.36 3 ↓
Mid Mid (pH 6-8) 2.09 7.5 -39.57 1 4 0 58 258.368 3 ↓

Analogs

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Popular Name: 4-propyl-2-thiomorpholino-thiazole-5-carboxylic 4-propyl-2-thiomorpholino-thiazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.59 7.94 -49.59 0 4 -1 56 271.387 4 ↓
Mid Mid (pH 6-8) 2.59 8.28 -39.68 1 4 0 58 272.395 4 ↓

Analogs

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Popular Name: N-[(4-propyl-2-thiomorpholino-thiazol-5-yl)methyl]ethanamine N-[(4-propyl-2-thiomorpholino-th…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.95 8.19 -40.9 2 3 1 33 286.49 6 ↓
Hi High (pH 8-9.5) 2.95 6.82 -4.65 1 3 0 28 285.482 6 ↓

Analogs

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Popular Name: N-[(4-propyl-2-thiomorpholino-thiazol-5-yl)methyl]propan-1-amine N-[(4-propyl-2-thiomorpholino-th…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.45 8.94 -41.64 2 3 1 33 300.517 7 ↓
Hi High (pH 8-9.5) 3.45 7.59 -4.56 1 3 0 28 299.509 7 ↓

Analogs

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Popular Name: N-[(4-propyl-2-thiomorpholino-thiazol-5-yl)methyl]propan-2-amine N-[(4-propyl-2-thiomorpholino-th…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.25 8.69 -39.02 2 3 1 33 300.517 6 ↓
Hi High (pH 8-9.5) 3.25 7.51 -4.5 1 3 0 28 299.509 6 ↓

Analogs

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Popular Name: 2-methyl-N-[(4-propyl-2-thiomorpholino-thiazol-5-yl)methyl]propan-2-amine 2-methyl-N-[(4-propyl-2-thiomorp…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.76 9.13 -36.99 2 3 1 33 314.544 6 ↓
Hi High (pH 8-9.5) 3.76 7.92 -4.43 1 3 0 28 313.536 6 ↓

Analogs

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Popular Name: 2-methyl-N-[(4-propyl-2-thiomorpholino-thiazol-5-yl)methyl]propan-1-amine 2-methyl-N-[(4-propyl-2-thiomorp…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.70 9.63 -41.33 2 3 1 33 314.544 7 ↓
Hi High (pH 8-9.5) 3.70 8.42 -4.4 1 3 0 28 313.536 7 ↓

Analogs

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Popular Name: 2-methoxy-N-[(4-propyl-2-thiomorpholino-thiazol-5-yl)methyl]ethanamine 2-methoxy-N-[(4-propyl-2-thiomor…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.56 7.33 -41.35 2 4 1 42 316.516 8 ↓
Mid Mid (pH 6-8) 2.56 5.9 -6.58 1 4 0 37 315.508 8 ↓

Analogs

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Popular Name: (4-methyl-2-thiomorpholino-thiazol-5-yl)methanamine (4-methyl-2-thiomorpholino-thiaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.13 3.88 -47.29 3 3 1 44 230.382 2 ↓
Mid Mid (pH 6-8) 1.13 3.49 -5.73 2 3 0 42 229.374 2 ↓

Analogs

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Popular Name: (4-tert-butyl-2-thiomorpholino-thiazol-5-yl)methanamine (4-tert-butyl-2-thiomorpholino-t…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.85 5.78 -47.44 3 3 1 44 272.463 3 ↓
Mid Mid (pH 6-8) 2.85 5.46 -5.29 2 3 0 42 271.455 3 ↓

Analogs

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Popular Name: (4-ethyl-2-thiomorpholino-thiazol-5-yl)methanamine (4-ethyl-2-thiomorpholino-thiazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.70 4.67 -47.4 3 3 1 44 244.409 3 ↓
Mid Mid (pH 6-8) 1.70 4.22 -5.39 2 3 0 42 243.401 3 ↓

Analogs

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Popular Name: (4-propyl-2-thiomorpholino-thiazol-5-yl)methanamine (4-propyl-2-thiomorpholino-thiaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.20 5.46 -47.95 3 3 1 44 258.436 4 ↓
Mid Mid (pH 6-8) 2.20 5 -5.34 2 3 0 42 257.428 4 ↓

Parameters Provided:

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