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Search Results | ZINC Is Not Commercial - A database of commercially-available compounds
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Analogs

15785311
15785311

Draw Identity 99% 90% 80% 70%

Popular Name: (4S,5S)-5-ethyl-5-methyl-4-phenyl-oxazolidine-2-thione (4S,5S)-5-ethyl-5-methyl-4-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.24 5.02 -13.28 1 2 0 21 221.325 2 ↓

Analogs

15785311
15785311

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Popular Name: (4R,5R)-5-ethyl-5-methyl-4-phenyl-oxazolidine-2-thione (4R,5R)-5-ethyl-5-methyl-4-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.24 5.02 -13.34 1 2 0 21 221.325 2 ↓

Analogs

15785311
15785311

Draw Identity 99% 90% 80% 70%

Popular Name: (4R,5S)-5-ethyl-5-methyl-4-phenyl-oxazolidine-2-thione (4R,5S)-5-ethyl-5-methyl-4-pheny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.24 5.03 -13.19 1 2 0 21 221.325 2 ↓

Analogs

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Popular Name: 3-[[cyclopropyl-[(3,4-dichlorophenyl)methyl]amino]methyl]oxazolidine-2-thione 3-[[cyclopropyl-[(3,4-dichloroph…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.66 6.92 -12.53 0 3 0 16 331.268 5 ↓
Lo Low (pH 4.5-6) 3.66 9.86 -52.92 1 3 1 17 332.276 5 ↓

Analogs

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Popular Name: 3-[(8-fluoro-6-methyl-3,4-dihydro-2H-quinolin-1-yl)methyl]oxazolidine-2-thione 3-[(8-fluoro-6-methyl-3,4-dihydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.34 7.46 -9.71 0 3 0 16 280.368 2 ↓

Analogs

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Popular Name: 3-[[(2R)-2-[(1S)-1-phenylpropyl]pyrrolidin-1-yl]methyl]oxazolidine-2-thione 3-[[(2R)-2-[(1S)-1-phenylpropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.95 9.36 -11.65 0 3 0 16 304.459 5 ↓
Mid Mid (pH 6-8) 3.95 9.69 -44.73 1 3 1 17 305.467 5 ↓

Analogs

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Popular Name: 3-[[(2S)-2-[(2-methoxyphenyl)methyl]pyrrolidin-1-yl]methyl]oxazolidine-2-thione 3-[[(2S)-2-[(2-methoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.81 5.9 -10.99 0 4 0 25 306.431 5 ↓
Mid Mid (pH 6-8) 2.81 8.13 -42.62 1 4 1 26 307.439 5 ↓

Analogs

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Popular Name: 3-[[(3-methoxy-4-methylsulfanyl-phenyl)methyl-methyl-amino]methyl]oxazolidine-2-thione 3-[[(3-methoxy-4-methylsulfanyl-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.43 5.14 -17.58 0 4 0 25 312.46 6 ↓
Lo Low (pH 4.5-6) 2.43 7.63 -56.99 1 4 1 26 313.468 6 ↓

Analogs

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Popular Name: 4-[4-[(2-thioxooxazolidin-3-yl)methyl]piperazin-1-yl]sulfonylbenzonitrile 4-[4-[(2-thioxooxazolidin-3-yl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.17 4.03 -24.54 0 7 0 77 366.468 4 ↓

Analogs

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Popular Name: 3-[[4-(4-methoxy-3-nitro-phenyl)sulfonylpiperazin-1-yl]methyl]oxazolidine-2-thione 3-[[4-(4-methoxy-3-nitro-phenyl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 4.4 -26.99 0 10 0 108 416.481 6 ↓

Analogs

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Popular Name: 3-[[4-(4-ethoxyphenyl)sulfonylpiperazin-1-yl]methyl]oxazolidine-2-thione 3-[[4-(4-ethoxyphenyl)sulfonylpi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.84 3.88 -22.14 0 7 0 62 385.511 6 ↓

Analogs

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Popular Name: (2,3-dichlorophenyl)-[4-[(2-thioxooxazolidin-3-yl)methyl]piperazin-1-yl]methanone (2,3-dichlorophenyl)-[4-[(2-thio…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.33 5.57 -20.41 0 5 0 36 374.293 3 ↓

Analogs

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Popular Name: N-[(1S,3R)-3-methylcyclohexyl]-2-[4-[(2-thioxooxazolidin-3-yl)methyl]piperazin-1-yl]acetamide N-[(1S,3R)-3-methylcyclohexyl]-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.02 3.29 -19.74 1 6 0 48 354.52 5 ↓
Lo Low (pH 4.5-6) 2.02 5.73 -49.22 2 6 1 49 355.528 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1S,3S)-3-methylcyclohexyl]-2-[4-[(2-thioxooxazolidin-3-yl)methyl]piperazin-1-yl]acetamide N-[(1S,3S)-3-methylcyclohexyl]-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.02 3.55 -16.93 1 6 0 48 354.52 5 ↓
Lo Low (pH 4.5-6) 2.02 5.95 -49.9 2 6 1 49 355.528 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,3R)-3-methylcyclohexyl]-2-[4-[(2-thioxooxazolidin-3-yl)methyl]piperazin-1-yl]acetamide N-[(1R,3R)-3-methylcyclohexyl]-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.02 3.54 -16.74 1 6 0 48 354.52 5 ↓
Lo Low (pH 4.5-6) 2.02 5.96 -49.78 2 6 1 49 355.528 5 ↓

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[(1R,3S)-3-methylcyclohexyl]-2-[4-[(2-thioxooxazolidin-3-yl)methyl]piperazin-1-yl]acetamide N-[(1R,3S)-3-methylcyclohexyl]-2…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.02 3.29 -19.7 1 6 0 48 354.52 5 ↓
Lo Low (pH 4.5-6) 2.02 5.73 -49.16 2 6 1 49 355.528 5 ↓

Analogs

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Popular Name: 2-fluoro-N-[2-[4-[(2-thioxooxazolidin-3-yl)methyl]piperazin-1-yl]ethyl]benzamide 2-fluoro-N-[2-[4-[(2-thioxooxazo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.44 2.7 -23.56 1 6 0 48 366.462 6 ↓
Mid Mid (pH 6-8) 1.44 4.98 -57.72 2 6 1 49 367.47 6 ↓

Analogs

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Popular Name: 1-(4-ethylpiperazin-1-yl)-2-[1-[(2-thioxooxazolidin-3-yl)methyl]-4-piperidyl]ethanone 1-(4-ethylpiperazin-1-yl)-2-[1-[…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.46 6.73 -50.74 1 6 1 40 355.528 5 ↓
Mid Mid (pH 6-8) 1.46 4.31 -19.79 0 6 0 39 354.52 5 ↓
Mid Mid (pH 6-8) 1.46 6.54 -53.43 1 6 1 40 355.528 5 ↓

Analogs

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Popular Name: 2-[propyl-[(2-thioxooxazolidin-3-yl)methyl]amino]acetonitrile 2-[propyl-[(2-thioxooxazolidin-3…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.27 3.07 -23.86 0 4 0 40 213.306 5 ↓

Analogs

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Popular Name: 2-cyclopentyl-N-[1-[(2-thioxooxazolidin-3-yl)methyl]-4-piperidyl]acetamide 2-cyclopentyl-N-[1-[(2-thioxooxa…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.16 7.14 -54.04 2 5 1 46 326.486 5 ↓
Mid Mid (pH 6-8) 2.16 4.74 -17.55 1 5 0 45 325.478 5 ↓

Analogs

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Popular Name: 1-(4-methylpiperazin-1-yl)-2-[1-[(2-thioxooxazolidin-3-yl)methyl]-4-piperidyl]ethanone 1-(4-methylpiperazin-1-yl)-2-[1-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.08 5.93 -50.9 1 6 1 40 341.501 4 ↓
Mid Mid (pH 6-8) 1.08 5.88 -54.64 1 6 1 40 341.501 4 ↓
Mid Mid (pH 6-8) 1.08 8.28 -97.96 2 6 2 42 342.509 4 ↓

Analogs

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Popular Name: (2,6-dichlorophenyl)-[4-[(2-thioxooxazolidin-3-yl)methyl]piperazin-1-yl]methanone (2,6-dichlorophenyl)-[4-[(2-thio…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.33 5.6 -22.81 0 5 0 36 374.293 3 ↓

Analogs

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Popular Name: 3-[[(5-bromo-2-furyl)methyl-methyl-amino]methyl]oxazolidine-2-thione 3-[[(5-bromo-2-furyl)methyl-meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.20 6.17 -55.37 1 4 1 30 306.205 4 ↓

Analogs

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Popular Name: 3-[[(2S)-2-[(1S)-1-phenylpropyl]pyrrolidin-1-yl]methyl]oxazolidine-2-thione 3-[[(2S)-2-[(1S)-1-phenylpropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.95 6.27 -13.05 0 3 0 16 304.459 5 ↓
Mid Mid (pH 6-8) 3.95 9.01 -41.41 1 3 1 17 305.467 5 ↓

Analogs

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Popular Name: 3-[[(2S)-2-[(1R)-1-phenylpropyl]pyrrolidin-1-yl]methyl]oxazolidine-2-thione 3-[[(2S)-2-[(1R)-1-phenylpropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.95 7.68 -9.92 0 3 0 16 304.459 5 ↓
Mid Mid (pH 6-8) 3.95 9.93 -43.51 1 3 1 17 305.467 5 ↓

Analogs

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Popular Name: 3-[[(2R)-2-[(1R)-1-phenylpropyl]pyrrolidin-1-yl]methyl]oxazolidine-2-thione 3-[[(2R)-2-[(1R)-1-phenylpropyl]…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.95 7.78 -13.57 0 3 0 16 304.459 5 ↓
Mid Mid (pH 6-8) 3.95 9.63 -44.56 1 3 1 17 305.467 5 ↓

Analogs

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Popular Name: 3-[[(2R)-2-[(2-methoxyphenyl)methyl]pyrrolidin-1-yl]methyl]oxazolidine-2-thione 3-[[(2R)-2-[(2-methoxyphenyl)met…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.81 6.11 -16.35 0 4 0 25 306.431 5 ↓
Mid Mid (pH 6-8) 2.81 8.17 -45.32 1 4 1 26 307.439 5 ↓

Analogs

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Popular Name: 3-[[(3R)-3-(morpholinomethyl)-1-piperidyl]methyl]oxazolidine-2-thione 3-[[(3R)-3-(morpholinomethyl)-1-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.26 2.41 -13.93 0 5 0 28 299.44 4 ↓
Mid Mid (pH 6-8) 1.26 4.4 -51.49 1 5 1 29 300.448 4 ↓
Mid Mid (pH 6-8) 1.26 4.79 -50.26 1 5 1 29 300.448 4 ↓

Analogs

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Popular Name: 3-[[(3S)-3-(morpholinomethyl)-1-piperidyl]methyl]oxazolidine-2-thione 3-[[(3S)-3-(morpholinomethyl)-1-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.26 2.52 -15.24 0 5 0 28 299.44 4 ↓
Mid Mid (pH 6-8) 1.26 4.55 -45.95 1 5 1 29 300.448 4 ↓
Mid Mid (pH 6-8) 1.26 4.92 -50.25 1 5 1 29 300.448 4 ↓

Analogs

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Popular Name: N-[[1-[(2-thioxooxazolidin-3-yl)methyl]-4-piperidyl]methyl]acetamide N-[[1-[(2-thioxooxazolidin-3-yl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.53 4.63 -58.8 2 5 1 46 272.394 4 ↓
Mid Mid (pH 6-8) 0.53 2.21 -21.48 1 5 0 45 271.386 4 ↓

Analogs

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Popular Name: 3-[[4-(6-chloro-2-pyridyl)piperazin-1-yl]methyl]oxazolidine-2-thione 3-[[4-(6-chloro-2-pyridyl)pipera…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.32 5.1 -18.8 0 5 0 32 312.826 3 ↓
Mid Mid (pH 6-8) 2.32 7.75 -52.1 1 5 1 33 313.834 3 ↓

Analogs

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Popular Name: 3-[[(1R,4S)-4-(2-chlorophenyl)-1-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]methyl]oxazolidine 3-[[(1R,4S)-4-(2-chlorophenyl)-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.01 9.41 -17.76 1 4 0 32 411.958 3 ↓
Lo Low (pH 4.5-6) 5.01 11.72 -51.85 2 4 1 33 412.966 3 ↓

Analogs

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Popular Name: 3-[[(1S,4S)-4-(2-chlorophenyl)-1-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]methyl]oxazolidine 3-[[(1S,4S)-4-(2-chlorophenyl)-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 5.01 8.95 -17.89 1 4 0 32 411.958 3 ↓
Lo Low (pH 4.5-6) 5.01 11.35 -53.43 2 4 1 33 412.966 3 ↓

Analogs

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Popular Name: 3-[[(3R)-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1-piperidyl]methyl]oxazolidine-2-thione 3-[[(3R)-3-(3-methyl-1,2,4-oxadi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.69 4.57 -55.51 1 6 1 56 283.377 3 ↓
Mid Mid (pH 6-8) 0.69 2.16 -19.09 0 6 0 55 282.369 3 ↓

Analogs

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Popular Name: 3-[[(3S)-3-(3-methyl-1,2,4-oxadiazol-5-yl)-1-piperidyl]methyl]oxazolidine-2-thione 3-[[(3S)-3-(3-methyl-1,2,4-oxadi…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.69 4.38 -54.81 1 6 1 56 283.377 3 ↓
Mid Mid (pH 6-8) 0.69 1.99 -16.13 0 6 0 55 282.369 3 ↓

Analogs

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Popular Name: 3-[[4-(3-methyl-1,2,4-oxadiazol-5-yl)-1-piperidyl]methyl]oxazolidine-2-thione 3-[[4-(3-methyl-1,2,4-oxadiazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.69 4.59 -60.03 1 6 1 56 283.377 3 ↓
Hi High (pH 8-9.5) 0.69 2.18 -20.68 0 6 0 55 282.369 3 ↓

Analogs

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Popular Name: 3-[[[(1R)-indan-1-yl]-prop-2-ynyl-amino]methyl]oxazolidine-2-thione 3-[[[(1R)-indan-1-yl]-prop-2-yny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 6.27 -11.51 0 3 0 16 286.4 4 ↓
Lo Low (pH 4.5-6) 2.62 9.08 -39.21 1 3 1 17 287.408 4 ↓

Analogs

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Popular Name: 3-[[[(1S)-indan-1-yl]-prop-2-ynyl-amino]methyl]oxazolidine-2-thione 3-[[[(1S)-indan-1-yl]-prop-2-yny…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.62 6.55 -15.89 0 3 0 16 286.4 4 ↓
Lo Low (pH 4.5-6) 2.62 9.33 -46.29 1 3 1 17 287.408 4 ↓

Analogs

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Popular Name: 1-[1-[(2-thioxooxazolidin-3-yl)methyl]-4-piperidyl]imidazolidin-2-one 1-[1-[(2-thioxooxazolidin-3-yl)m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.20 3.92 -57.45 2 6 1 49 285.393 3 ↓
Hi High (pH 8-9.5) 0.20 1.53 -26.35 1 6 0 48 284.385 3 ↓

Analogs

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Popular Name: 3-[[methyl-[(4-nitrophenyl)methyl]amino]methyl]oxazolidine-2-thione 3-[[methyl-[(4-nitrophenyl)methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.97 5.35 -19.47 0 6 0 62 281.337 5 ↓
Lo Low (pH 4.5-6) 1.97 7.81 -66.05 1 6 1 63 282.345 5 ↓

Analogs

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Popular Name: 3-[[4-(3-chloro-2-pyridyl)piperazin-1-yl]methyl]oxazolidine-2-thione 3-[[4-(3-chloro-2-pyridyl)pipera…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.93 5.19 -16.15 0 5 0 32 312.826 3 ↓
Mid Mid (pH 6-8) 1.93 7.84 -45.95 1 5 1 33 313.834 3 ↓

Analogs

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Popular Name: (3aR,7aR)-3a,4,5,6,7,7a-hexahydro-3H-1,3-benzoxazole-2-thione (3aR,7aR)-3a,4,5,6,7,7a-hexahydr…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.74 1.51 -10.08 1 2 0 21 157.238 0 ↓

Analogs

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Popular Name: 3-[[4-(5-bromo-2-pyridyl)piperazin-1-yl]methyl]oxazolidine-2-thione 3-[[4-(5-bromo-2-pyridyl)piperaz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.28 5.13 -14.2 0 5 0 32 357.277 3 ↓
Mid Mid (pH 6-8) 2.28 7.51 -53.09 1 5 1 33 358.285 3 ↓

Parameters Provided:

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