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Analogs

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Popular Name: N-[(1S)-1,2-dimethylpropyl]-5-methyl-1-(2-pyridyl)pyrazole-4-carboxamide N-[(1S)-1,2-dimethylpropyl]-5-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.98 6.94 -11.64 1 5 0 60 272.352 4 ↓

Analogs

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Popular Name: N-[(1R)-1,2-dimethylpropyl]-5-methyl-1-(2-pyridyl)pyrazole-4-carboxamide N-[(1R)-1,2-dimethylpropyl]-5-me…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.98 7.22 -11.8 1 5 0 60 272.352 4 ↓

Analogs

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Popular Name: N-[2-(dimethylamino)-2-oxo-ethyl]-5-isopropyl-1-[5-(trifluoromethyl)-2-pyridyl]pyrazole-4-carboxamid N-[2-(dimethylamino)-2-oxo-ethyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.39 6.66 -10.57 1 7 0 80 383.374 6 ↓

Analogs

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Popular Name: 5-isopropyl-N-[(1S)-2-methoxy-1-methyl-ethyl]-1-[5-(trifluoromethyl)-2-pyridyl]pyrazole-4-carboxamid 5-isopropyl-N-[(1S)-2-methoxy-1-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 7.14 -8.21 1 6 0 69 370.375 7 ↓

Analogs

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Popular Name: 5-isopropyl-N-[(1R)-2-methoxy-1-methyl-ethyl]-1-[5-(trifluoromethyl)-2-pyridyl]pyrazole-4-carboxamid 5-isopropyl-N-[(1R)-2-methoxy-1-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.80 7.14 -8.14 1 6 0 69 370.375 7 ↓

Analogs

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Popular Name: 2-(4-bromopyrazol-1-yl)-3-methyl-5-nitro-pyridine 2-(4-bromopyrazol-1-yl)-3-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.43 7.18 -5.28 0 6 0 77 283.085 2 ↓

Analogs

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Popular Name: 2-(4-bromo-3,5-dimethyl-pyrazol-1-yl)-3-methyl-5-nitro-pyridine 2-(4-bromo-3,5-dimethyl-pyrazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.87 8.1 -5.89 0 6 0 77 311.139 2 ↓

Analogs

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Popular Name: 2-[3,5-dimethyl-1-(3-methyl-5-nitro-2-pyridyl)pyrazol-4-yl]acetic 2-[3,5-dimethyl-1-(3-methyl-5-ni…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.49 8.73 -47.94 0 8 -1 117 289.271 4 ↓

Analogs

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Popular Name: 3,5-dimethyl-1-(3-methyl-5-nitro-2-pyridyl)pyrazole-4-carboxylic 3,5-dimethyl-1-(3-methyl-5-nitro…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.63 8 -45.64 0 8 -1 117 275.244 3 ↓

Analogs

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Popular Name: 1-(3-methyl-5-nitro-2-pyridyl)pyrazole-4-carboxylic 1-(3-methyl-5-nitro-2-pyridyl)py…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.19 7.18 -44.85 0 8 -1 117 247.19 3 ↓

Analogs

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Popular Name: 5-methyl-6-pyrazol-1-yl-pyridin-3-amine 5-methyl-6-pyrazol-1-yl-pyridin-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.21 3.74 -8.29 2 4 0 57 174.207 1 ↓

Analogs

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Popular Name: 6-(3,5-dimethylpyrazol-1-yl)-5-methyl-pyridin-3-amine 6-(3,5-dimethylpyrazol-1-yl)-5-m…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.66 4.7 -9.69 2 4 0 57 202.261 1 ↓

Analogs

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Popular Name: 5-methyl-6-(4-methylpyrazol-1-yl)pyridin-3-amine 5-methyl-6-(4-methylpyrazol-1-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.59 4.43 -8.29 2 4 0 57 188.234 1 ↓

Analogs

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Popular Name: 6-(4-chloropyrazol-1-yl)-5-methyl-pyridin-3-amine 6-(4-chloropyrazol-1-yl)-5-methy…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.82 4.27 -7.01 2 4 0 57 208.652 1 ↓

Analogs

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Popular Name: 6-(4-bromopyrazol-1-yl)-5-methyl-pyridin-3-amine 6-(4-bromopyrazol-1-yl)-5-methyl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.95 4.37 -6.95 2 4 0 57 253.103 1 ↓

Analogs

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Popular Name: 5-methyl-6-(3,4,5-trimethylpyrazol-1-yl)pyridin-3-amine 5-methyl-6-(3,4,5-trimethylpyraz…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.03 5.26 -10.02 2 4 0 57 216.288 1 ↓

Analogs

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Popular Name: 6-(4-ethyl-3,5-dimethyl-pyrazol-1-yl)-5-methyl-pyridin-3-amine 6-(4-ethyl-3,5-dimethyl-pyrazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.50 6.23 -9.62 2 4 0 57 230.315 2 ↓

Analogs

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Popular Name: 5-methyl-6-[3-(trifluoromethyl)pyrazol-1-yl]pyridin-3-amine 5-methyl-6-[3-(trifluoromethyl)p…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.35 4.7 -7.65 2 4 0 57 242.204 2 ↓

Analogs

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Popular Name: 6-(4-chloro-3,5-dimethyl-pyrazol-1-yl)-5-methyl-pyridin-3-amine 6-(4-chloro-3,5-dimethyl-pyrazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.26 5.19 -8.31 2 4 0 57 236.706 1 ↓

Analogs

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Popular Name: 6-(4-bromo-3,5-dimethyl-pyrazol-1-yl)-5-methyl-pyridin-3-amine 6-(4-bromo-3,5-dimethyl-pyrazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 5.27 -8.31 2 4 0 57 281.157 1 ↓

Analogs

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Popular Name: 5-amino-2-(3-methylpyrazol-1-yl)pyridine-3-carbonitrile 5-amino-2-(3-methylpyrazol-1-yl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.74 3.81 -12.87 2 5 0 81 199.217 1 ↓

Analogs

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Popular Name: 2-ethoxy-6-(3-methylpyrazol-1-yl)pyridin-3-amine 2-ethoxy-6-(3-methylpyrazol-1-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.62 3.07 -7.83 2 5 0 66 218.26 3 ↓

Analogs

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Popular Name: 2-isopropoxy-6-(3-methylpyrazol-1-yl)pyridin-3-amine 2-isopropoxy-6-(3-methylpyrazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.98 3.99 -7.66 2 5 0 66 232.287 3 ↓

Analogs

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Popular Name: 2-isobutoxy-6-(3-methylpyrazol-1-yl)pyridin-3-amine 2-isobutoxy-6-(3-methylpyrazol-1…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.36 4.56 -7.51 2 5 0 66 246.314 4 ↓

Analogs

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Popular Name: 2-tert-butoxy-6-(3-methylpyrazol-1-yl)pyridin-3-amine 2-tert-butoxy-6-(3-methylpyrazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.42 5.69 -7.01 2 5 0 66 246.314 3 ↓

Analogs

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Popular Name: 2-methoxy-6-(3-methylpyrazol-1-yl)pyridin-3-amine 2-methoxy-6-(3-methylpyrazol-1-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.24 2.13 -8.03 2 5 0 66 204.233 2 ↓

Analogs

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Popular Name: 6-(3-methylpyrazol-1-yl)-2-propoxy-pyridin-3-amine 6-(3-methylpyrazol-1-yl)-2-propo…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 3.87 -7.62 2 5 0 66 232.287 4 ↓

Analogs

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Popular Name: 5-methyl-6-(3-methylpyrazol-1-yl)pyridin-3-amine 5-methyl-6-(3-methylpyrazol-1-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.44 4.32 -8.61 2 4 0 57 188.234 1 ↓

Analogs

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Popular Name: 5-bromo-2-(3-methylpyrazol-1-yl)pyridin-3-amine 5-bromo-2-(3-methylpyrazol-1-yl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.80 4.53 -5.79 2 4 0 57 253.103 1 ↓

Analogs

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Popular Name: 5-amino-2-(3-methylpyrazol-1-yl)pyridine-3-carboxamide 5-amino-2-(3-methylpyrazol-1-yl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.19 0.57 -18.05 4 6 0 100 217.232 2 ↓

Analogs

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Popular Name: 2-(3-methylpyrazol-1-yl)pyridin-4-amine 2-(3-methylpyrazol-1-yl)pyridin-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.43 3.47 -8.92 2 4 0 57 174.207 1 ↓
Lo Low (pH 4.5-6) 0.43 3.89 -32.7 3 4 1 58 175.215 1 ↓

Analogs

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Popular Name: [2-(3-methylpyrazol-1-yl)-3-pyridyl]methanamine [2-(3-methylpyrazol-1-yl)-3-pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.54 4.2 -38.15 3 4 1 58 189.242 2 ↓
Mid Mid (pH 6-8) 0.54 3.74 -8.38 2 4 0 57 188.234 2 ↓

Analogs

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Popular Name: [2-(3-methylpyrazol-1-yl)-4-pyridyl]methanamine [2-(3-methylpyrazol-1-yl)-4-pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.54 3.62 -51.71 3 4 1 58 189.242 2 ↓
Mid Mid (pH 6-8) 0.54 3.23 -9.08 2 4 0 57 188.234 2 ↓

Analogs

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Popular Name: [6-(3-methylpyrazol-1-yl)-3-pyridyl]methanamine [6-(3-methylpyrazol-1-yl)-3-pyri…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.60 3.6 -54.76 3 4 1 58 189.242 2 ↓
Mid Mid (pH 6-8) 0.60 3.2 -7.85 2 4 0 57 188.234 2 ↓

Analogs

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Popular Name: [4,6-dimethyl-2-(3-methylpyrazol-1-yl)-3-pyridyl]methanamine [4,6-dimethyl-2-(3-methylpyrazol…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.36 5.14 -38.83 3 4 1 58 217.296 2 ↓
Mid Mid (pH 6-8) 1.36 4.75 -7.29 2 4 0 57 216.288 2 ↓

Analogs

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Popular Name: [6-methyl-2-(3-methylpyrazol-1-yl)-3-pyridyl]methanamine [6-methyl-2-(3-methylpyrazol-1-y…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.60 4.82 -38.25 3 4 1 58 203.269 2 ↓
Mid Mid (pH 6-8) 0.60 4.34 -8.48 2 4 0 57 202.261 2 ↓

Analogs

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Popular Name: 2-(3-methylpyrazol-1-yl)pyridine-4-carboxylic 2-(3-methylpyrazol-1-yl)pyridine…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.27 6.16 -50.83 0 5 -1 71 202.193 2 ↓

Analogs

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Popular Name: 5-chloro-6-(3-methylpyrazol-1-yl)pyridine-3-carboxylic 5-chloro-6-(3-methylpyrazol-1-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.59 6.77 -42.17 0 5 -1 71 236.638 2 ↓

Analogs

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Popular Name: 6-(3-methylpyrazol-1-yl)pyridine-3-carboxylic 6-(3-methylpyrazol-1-yl)pyridine…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.98 6.15 -44.37 0 5 -1 71 202.193 2 ↓

Analogs

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Popular Name: 2-(3-methylpyrazol-1-yl)pyridine-3-carboxylic 2-(3-methylpyrazol-1-yl)pyridine…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.93 6.36 -56.74 0 5 -1 71 202.193 2 ↓

Analogs

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Popular Name: 3-chloro-6-(3-methylpyrazol-1-yl)pyridine-2-carboxylic 3-chloro-6-(3-methylpyrazol-1-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.06 6.56 -48.59 0 5 -1 71 236.638 2 ↓

Analogs

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Popular Name: 2-chloro-6-(3-methylpyrazol-1-yl)pyridine-4-carboxylic 2-chloro-6-(3-methylpyrazol-1-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.29 6.59 -44.76 0 5 -1 71 236.638 2 ↓

Analogs

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Popular Name: 6-(3-methylpyrazol-1-yl)pyridine-2-carboxylic 6-(3-methylpyrazol-1-yl)pyridine…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.05 6.16 -50.93 0 5 -1 71 202.193 2 ↓

Analogs

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Popular Name: 4,6-dimethyl-2-(3-methylpyrazol-1-yl)pyridine-3-carboxylic 4,6-dimethyl-2-(3-methylpyrazol-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.75 7.59 -64.3 0 5 -1 71 230.247 2 ↓

Analogs

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Popular Name: 5-bromo-2-(3-methylpyrazol-1-yl)pyridine-3-carboxylic 5-bromo-2-(3-methylpyrazol-1-yl)…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.89 6.96 -50.37 0 5 -1 71 281.089 2 ↓

Analogs

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Popular Name: 6-chloro-2-(3-methylpyrazol-1-yl)-3-nitro-pyridine 6-chloro-2-(3-methylpyrazol-1-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.34 6.88 -11.93 0 6 0 77 238.634 2 ↓

Analogs

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Popular Name: 2-fluoro-6-(3-methylpyrazol-1-yl)pyridine 2-fluoro-6-(3-methylpyrazol-1-yl…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.91 5.55 -8.12 0 3 0 31 177.182 1 ↓

Analogs

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Popular Name: 5-amino-2-(3-isopropylpyrazol-1-yl)pyridine-3-carbonitrile 5-amino-2-(3-isopropylpyrazol-1-…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.80 5.08 -12.8 2 5 0 81 227.271 2 ↓

Analogs

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Popular Name: 6-(3-isopropylpyrazol-1-yl)pyridin-3-amine 6-(3-isopropylpyrazol-1-yl)pyrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 4.75 -8.37 2 4 0 57 202.261 2 ↓

Analogs

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Popular Name: 2-(3-isopropylpyrazol-1-yl)pyridin-3-amine 2-(3-isopropylpyrazol-1-yl)pyrid…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.90 5.2 -7.67 2 4 0 57 202.261 2 ↓

Parameters Provided:

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Structural Results Found: (before additional filtering)

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