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ZINC Item

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35368425

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(2,5-dimethylphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.77	10.37	-7.43	0	1	0	17	256.37	2	↓ MOL2 SDF SMILES Flexibase

35368439

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(2,3,5,6-tetramethylphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.53	11.34	-7.68	0	1	0	17	284.424	2	↓ MOL2 SDF SMILES Flexibase

35368454

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(2,5-dimethoxyphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.99	8.55	-11.13	0	3	0	36	288.368	4	↓ MOL2 SDF SMILES Flexibase

35368468

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(2,3,4,5,6-pentamethylphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.90	11.82	-8.15	0	1	0	17	298.451	2	↓ MOL2 SDF SMILES Flexibase

35368482

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2,5-difluorophenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (2,5-difluorophenyl)-(5,6-dihydr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.21	8.82	-8.32	0	1	0	17	264.296	2	↓ MOL2 SDF SMILES Flexibase

35368512

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(2,4,6-trimethylphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.15	10.98	-7.45	0	1	0	17	270.397	2	↓ MOL2 SDF SMILES Flexibase

35368556

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(4-fluorophenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.11	8.75	-6.11	0	1	0	17	246.306	2	↓ MOL2 SDF SMILES Flexibase

35368569

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2,4-difluorophenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (2,4-difluorophenyl)-(5,6-dihydr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.21	8.82	-8.51	0	1	0	17	264.296	2	↓ MOL2 SDF SMILES Flexibase

35368594

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4-tert-butylphenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (4-tert-butylphenyl)-(5,6-dihydr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.66	11	-7	0	1	0	17	284.424	3	↓ MOL2 SDF SMILES Flexibase

35368614

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-[4-[(1R)-1-methylpropyl]phenyl]methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.81	11.25	-6.97	0	1	0	17	284.424	4	↓ MOL2 SDF SMILES Flexibase

35368615

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-[4-[(1S)-1-methylpropyl]phenyl]methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.81	11.25	-6.98	0	1	0	17	284.424	4	↓ MOL2 SDF SMILES Flexibase

35368638

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4-butylphenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (4-butylphenyl)-(5,6-dihydro-4H-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.81	11.68	-7.2	0	1	0	17	284.424	5	↓ MOL2 SDF SMILES Flexibase

35368653

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(2,4-dimethylphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.77	10.37	-7.25	0	1	0	17	256.37	2	↓ MOL2 SDF SMILES Flexibase

35368667

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-(5,6-dihydro-4H-cyclopenta[b]thiophene-2-carbonyl)phenyl]acetamide N-[4-(5,6-dihydro-4H-cyclopenta[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.17	7.59	-14.35	1	3	0	46	285.368	3	↓ MOL2 SDF SMILES Flexibase

35368694

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(4-propylphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.25	10.9	-7.18	0	1	0	17	270.397	4	↓ MOL2 SDF SMILES Flexibase

35368732

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(4-isobutylphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.25	11.36	-7.1	0	1	0	17	284.424	4	↓ MOL2 SDF SMILES Flexibase

35368760

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(4-iodophenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.03	9.78	-5.56	0	1	0	17	354.212	2	↓ MOL2 SDF SMILES Flexibase

35368774

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3,4-difluorophenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (3,4-difluorophenyl)-(5,6-dihydr…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.21	8.87	-5.55	0	1	0	17	264.296	2	↓ MOL2 SDF SMILES Flexibase

35368785

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl(phenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.95	8.68	-7.93	0	1	0	17	228.316	2	↓ MOL2 SDF SMILES Flexibase

35368795

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4-chlorophenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (4-chlorophenyl)-(5,6-dihydro-4H…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.63	9.2	-5.84	0	1	0	17	262.761	2	↓ MOL2 SDF SMILES Flexibase

35368806

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (4-bromophenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (4-bromophenyl)-(5,6-dihydro-4H-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.76	9.3	-5.75	0	1	0	17	307.212	2	↓ MOL2 SDF SMILES Flexibase

35368818

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(4-ethylphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.86	10.12	-7.29	0	1	0	17	256.37	3	↓ MOL2 SDF SMILES Flexibase

35368832

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(4-ethoxyphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.38	8.92	-7.32	0	2	0	26	272.369	4	↓ MOL2 SDF SMILES Flexibase

35368843

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(4-methoxyphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.01	7.99	-7.59	0	2	0	26	258.342	3	↓ MOL2 SDF SMILES Flexibase

35368883

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(2,4,6-trifluorophenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.30	9.31	-7.16	0	1	0	17	282.286	2	↓ MOL2 SDF SMILES Flexibase

35368985

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl(p-tolyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.40	9.36	-7.63	0	1	0	17	242.343	2	↓ MOL2 SDF SMILES Flexibase

35368995

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(3,4-dimethoxyphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.60	7.9	-9.86	0	3	0	36	288.368	4	↓ MOL2 SDF SMILES Flexibase

35369052

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (2-bromo-4,5-dimethoxy-phenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (2-bromo-4,5-dimethoxy-phenyl)-(…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.33	8.62	-8.57	0	3	0	36	367.264	4	↓ MOL2 SDF SMILES Flexibase

35369078

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: N-[4-(5,6-dihydro-4H-cyclopenta[b]thiophene-2-carbonyl)phenyl]methanesulfonamide N-[4-(5,6-dihydro-4H-cyclopenta[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.18	5.31	-16.09	1	4	0	63	321.423	4	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.18	5.55	-42.72	0	4	-1	65	320.415	4	↓ MOL2 SDF SMILES Flexibase

35369230

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(4-isopropoxyphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.75	9.52	-7.55	0	2	0	26	286.396	4	↓ MOL2 SDF SMILES Flexibase

35369257

Analogs

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Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(5-fluoro-2-methoxy-phenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.10	9.33	-9.35	0	2	0	26	276.332	3	↓ MOL2 SDF SMILES Flexibase

35369300

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(5-iodo-2-methoxy-phenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.02	10.35	-8.89	0	2	0	26	384.238	3	↓ MOL2 SDF SMILES Flexibase

35369326

Analogs

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Popular Name: (3-chloro-4-methoxy-phenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (3-chloro-4-methoxy-phenyl)-(5,6…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.61	8.54	-7.06	0	2	0	26	292.787	3	↓ MOL2 SDF SMILES Flexibase

35369344

Analogs

Draw Identity 99% 90% 80% 70%

Popular Name: (3-bromo-4-methoxy-phenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (3-bromo-4-methoxy-phenyl)-(5,6-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.74	8.65	-7.1	0	2	0	26	337.238	3	↓ MOL2 SDF SMILES Flexibase

35369362

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Popular Name: (5-bromo-2-methoxy-phenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (5-bromo-2-methoxy-phenyl)-(5,6-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.74	9.87	-9.12	0	2	0	26	337.238	3	↓ MOL2 SDF SMILES Flexibase

35369383

Analogs

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Popular Name: 5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl-(3,4-dimethylphenyl)methanone 5,6-dihydro-4H-cyclopenta[b]thio…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.77	9.9	-7.9	0	1	0	17	256.37	2	↓ MOL2 SDF SMILES Flexibase

35369595

Analogs

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Popular Name: (2-chloro-4,5-dimethoxy-phenyl)-(5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)methanone (2-chloro-4,5-dimethoxy-phenyl)-…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.20	8.51	-8.96	0	3	0	36	322.813	4	↓ MOL2 SDF SMILES Flexibase

35369655

Analogs

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Popular Name: N-[4-(5,6-dihydro-4H-cyclopenta[b]thiophene-2-carbonyl)phenyl]-N-methyl-formamide N-[4-(5,6-dihydro-4H-cyclopenta[…

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Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.44	8.45	-11.68	0	3	0	37	285.368	3	↓ MOL2 SDF SMILES Flexibase

Parameters Provided:

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Structural Results Found: (before additional filtering)

SQL Query Was

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